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01-07-2012

Preoperative Treatment Does Not Improve the Therapeutic Results of Abdominosacral Amputation of the Rectum

Authors: Marek Bębenek, Wiesław Tupikowski, Karol Cisarż, Alicja Balcerzak, Leszek Wojciechowski, Anna Stankowska, Radosław Tarkowski

Published in: World Journal of Surgery | Issue 7/2012

Abstract

Background

This study reviewed the impact of preoperative chemoradiotherapy/short-term radiotherapy on abdominosacral amputations of the rectum (ASAR) for the treatment of low-rectum cancers in terms of postoperative morbidity, local recurrence rates, and survival.

Methods

A total of 198 patients with stage II and III tumors located within 6 cm of the anorectal junction underwent ASAR between 1998 and 2008 and were selected for further analysis. Patients were compared according to the following groups: those who had surgery only (Group A) and those who had preoperative chemoradiotherapy/short-term radiotherapy (Group B).

Results

There were 44 and 154 patients in Groups A and B, respectively, including 135 males. The median age of the subjects was 63 years (range = 35–88). The median follow-up period was 81 months (range = 23–138). Neither the local recurrence rates (6.8% in Group A vs. 4.6% in Group B, p = 0.544) nor the 5-year relative survival rates (72.4% in Group A vs. 69.3% in Group B, p = 0.127) differed significantly between the groups.

Conclusion

Preoperative therapy in low-rectum cancer does not improve the therapeutic results of ASAR.

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Title: Preoperative Treatment Does Not Improve the Therapeutic Results of Abdominosacral Amputation of the Rectum
Authors: Marek Bębenek
Wiesław Tupikowski
Karol Cisarż
Alicja Balcerzak
Leszek Wojciechowski
Anna Stankowska
Radosław Tarkowski
Publication date: 01-07-2012
Publisher: Springer-Verlag
Published in: World Journal of Surgery / Issue 7/2012
Print ISSN: 0364-2313
Electronic ISSN: 1432-2323
DOI: https://doi.org/10.1007/s00268-012-1527-y

At a glance: The STEP trials

Springer Medicine

Preoperative Treatment Does Not Improve the Therapeutic Results of Abdominosacral Amputation of the Rectum

Abstract

Background

Methods

Results

Conclusion

At a glance: The STEP trials

Springer Medicine

Abstract

Background

Methods

Results

Conclusion

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