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Journal of Anesthesia
Published in: Journal of Anesthesia 4/2016

01-08-2016 | Original Article

Preoperative serum lactate cannot predict in-hospital mortality after decompressive craniectomy in traumatic brain injury

Authors: Youn Yi Jo, Ji Young Kim, Jung Ju Choi, Wol Seon Jung, Yong Beom Kim, Hyun Jeong Kwak

Published in: Journal of Anesthesia | Issue 4/2016

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Abstract

Purpose

Despite the utility of serum lactate for predicting clinical courses, little information is available on the topic after decompressive craniectomy. This study was conducted to determine the ability of perioperative serum lactate levels to predict in-hospital mortality in traumatic brain-injury patients who received emergency or urgent decompressive craniectomy.

Methods

The medical records of 586 consecutive patients who underwent emergency or urgent decompressive craniectomy due to traumatic brain injuries from January 2007 to December 2014 were retrospectively analyzed. Pre- and intraoperative serum lactate levels and base deficits were obtained from arterial blood gas analysis results.

Results

The overall mortality rate after decompressive craniectomy was 26.1 %. Mean preoperative serum lactate was significantly higher in the non-survivors (P = 0.034) than the survivors but had no significance for predicting in-hospital mortality in the multivariate regression analysis (P = 0.386). Rather, preoperative Glasgow Coma Score was a significant predictor for in-hospital mortality (hazard ratio 0.796, 95 % confidence interval 0.755–0.836, P < 0.001).

Conclusion

Preoperative lactate level is not an independent predictor of in-hospital mortality after decompressive craniectomy in traumatic brain-injury patients.
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Metadata
Title
Preoperative serum lactate cannot predict in-hospital mortality after decompressive craniectomy in traumatic brain injury
Authors
Youn Yi Jo
Ji Young Kim
Jung Ju Choi
Wol Seon Jung
Yong Beom Kim
Hyun Jeong Kwak
Publication date
01-08-2016
Publisher
Springer Japan
Published in
Journal of Anesthesia / Issue 4/2016
Print ISSN: 0913-8668
Electronic ISSN: 1438-8359
DOI
https://doi.org/10.1007/s00540-016-2169-2

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