Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on medication adherence

LIVE: Thursday 27th June 2024, 18:00-19:30 (CEST)
Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.
ADVANCED SEARCH
Log in
Top
Pediatric Radiology
Published in: Pediatric Radiology 7/2006

01-07-2006 | Case Report

Prenatal detection of microtia by MRI in a fetus with trisomy 22

Authors: Andrea Milic, Susan Blaser, Ashley Robinson, Sandra Viero, William Halliday, Elizabeth Winsor, Ants Toi, Micki Thomas, David Chitayat

Published in: Pediatric Radiology | Issue 7/2006

Login to get access

Abstract

Trisomy 22 is a rare chromosomal abnormality infrequently detected prenatally. External ear abnormalities, in particular microtia, are often associated with trisomy 22, but prenatal detection of microtia has not been reported in association with trisomy 22. We report a fetus with trisomy 22, with fetal MRI findings of microtia, craniofacial dysmorphism, and polygyria. Fetal MRI is a useful tool for auricular assessment and might have utility in the prenatal detection of chromosomal abnormalities, especially among fetuses with structural anomalies.
Literature
1.
Bacino CA, Schreck R, Fischel-Ghodsian N, et al (1995) Clinical and molecular studies in full trisomy 22: further delineation of the phenotype and review of the literature. Am J Med Genet 56:359–365PubMedCrossRef
2.
Sepulveda W, Be C, Schnapp C, et al (2003) Second-trimester sonographic findings in trisomy 22. J Ultrasound Med 22:1271–1275PubMed
3.
Birnholtz JC, Farrell EE (1988) Fetal ear length. Pediatrics 81:555–558
4.
Lettieri L, Rodis JF, Vintzileos AM, et al (1993) Ear length in second-trimester aneuploid fetuses. Obstet Gynecol 81:57–60PubMed
5.
Awwad JT, Azar GB, Karam KS, et al (1994) Ear length: a potential sonographic marker of Down syndrome. Int J Gynecol Obstet 44:233–238CrossRef
6.
Shimizu T, Salvador L, Huges-Benzie R, et al (1997) The role of reduced ear size in the prenatal detection of chromosomal abnormalities. Prenat Diagn 17:545–549PubMedCrossRef
7.
Sivan Y, Merlob P, Reisner SH (1983) Assessment of ear length and low set ears in newborn infants. J Med Genet 20:213–215PubMed
8.
Shih JC, Shyu MK, Lee CN, et al (1998) Antenatal depiction of the fetal ear with three-dimensional ultrasonography. Obstet Gynecol 91:500–505PubMedCrossRef
9.
Harris J, Kallen B, Robert E (1996) The epidemiology of anotia and microtia. J Med Genet 33:809–813PubMedCrossRef
Metadata
Title
Prenatal detection of microtia by MRI in a fetus with trisomy 22
Authors
Andrea Milic
Susan Blaser
Ashley Robinson
Sandra Viero
William Halliday
Elizabeth Winsor
Ants Toi
Micki Thomas
David Chitayat
Publication date
01-07-2006
Publisher
Springer-Verlag
Published in
Pediatric Radiology / Issue 7/2006
Print ISSN: 0301-0449
Electronic ISSN: 1432-1998
DOI
https://doi.org/10.1007/s00247-006-0155-9

Other articles of this Issue 7/2006

Pediatric Radiology 7/2006 Go to the issue

Original Article

Nutcracker syndrome in children with gross haematuria: Doppler sonographic evaluation of the left renal vein

Minisymposium

Magnetic resonance imaging in preterm infants

Minisymposium

New advances in fetal MR neuroimaging

Minisymposium

Neonatal brain imaging

Original Article

Objective CT criteria to determine the presence of abnormal basal enhancement in children with suspected tuberculous meningitis

Clinical Image

Infiltrative renal lymphangioma in a pediatric patient