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Journal of Medical Case Reports

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Open Access 01-12-2011 | Case report

Premature ovarian failure in a woman with a balanced 15;21 translocation: a case report

Authors: Sayedehafagh Hosseini, Marzieh Vahid Dastjerdi, Zahra Asgari, Haydeh Samiee

Published in: Journal of Medical Case Reports | Issue 1/2011

Abstract

Introduction

A case of premature ovarian failure with concomitant findings of Robertsonian translocation between 15 and 21 chromosomes is reported here. The aforementioned karyotypic aberration has not been reported in the context of premature ovarian failure to date.

Case presentation

We present a case of premature ovarian failure in a 27-year-old infertile Kurdish Iranian woman with a Robertsonian 15;21 translocation.

Conclusions

The diagnosis of premature ovarian failure of unknown etiology, but with karyotypic evidence of a balanced autosomal translocation, suggests the possible role of autosomal genes in the pathogenesis of ovarian follicular attrition.

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Title: Premature ovarian failure in a woman with a balanced 15;21 translocation: a case report
Authors: Sayedehafagh Hosseini
Marzieh Vahid Dastjerdi
Zahra Asgari
Haydeh Samiee
Publication date: 01-12-2011
Publisher: BioMed Central
Published in: Journal of Medical Case Reports / Issue 1/2011
Electronic ISSN: 1752-1947
DOI: https://doi.org/10.1186/1752-1947-5-250

At a glance: The STEP trials

Springer Medicine

Premature ovarian failure in a woman with a balanced 15;21 translocation: a case report

Abstract

Introduction

Case presentation

Conclusions

At a glance: The STEP trials

Springer Medicine

Abstract

Introduction

Case presentation

Conclusions

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