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BMC Pregnancy and Childbirth
Published in: BMC Pregnancy and Childbirth 1/2017

Open Access 01-12-2017 | Research article

Pregnancy-associated-cancer in the French West Indies (Martinique): maternal and neonatal outcomes

Authors: Kathleen Melan, Jean-Luc Volumenie, Gaël Wan-Ajouhu, Stephen Ulric-Gervaise, Jacqueline Veronique-Baudin, Clarisse Joachim

Published in: BMC Pregnancy and Childbirth | Issue 1/2017

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Abstract

Background

The management of pregnancy-associated-cancer (PAC) requires epidemiological evaluation of the pathways of care. The aim of this study was to describe maternal and neonatal outcomes of PAC in Martinique.

Methods

A retrospective study was conducted using data from medical records and the Martinique Cancer Registry for all PAC diagnosed between 1st January 2000 and 31st December 2014.

Results

Eighteen women were diagnosed with PAC: 17 during pregnancy and one during the postpartum period. Mean age at diagnosis was 35.7 ± 5.4 years. PAC were mainly gynecological cancers (12/18); the other sites were: lymphoma, brain, liver, colon, skin and unknown primary site. In most cases, PAC was detected in symptomatic individuals (72.2%). Nine women had nodal involvement or initial metastasis at diagnosis. No chemotherapy was administered in cases of preservation of pregnancy. Seven fetal losses caused by abortion and miscarriage were recorded, and 11 women conducted viable pregnancies. The main neonatal pathology observed was prematurity (58.3%).

Conclusion

Cancer management during pregnancy is a challenge for French West-Indies territories. A Caribbean Observatory of rare cancers could help to ensure a coordinated approach to support and monitoring for these patients.
Literature
1.
Réseaux nationaux pour cancers rares de l’adulte, appui à la décision, INCa. 2015.
2.
DIEYE M, Véronique-Baudin J, Macni J, Pomier A, Malsa S, Picotti C, et al. L’incidence et la mortalité par cancer en Martinique entre 2006 et 2010: Données du Registre général des cancers de la Martinique. 2013.
3.
Fritz A, Percy C, Jack A, Shanmugaratnam K, Sobin L, Parkin DM, et al. International Classification of Diseases for Oncology (ICD-O-3). Third edition. Geneva: World Health Organization; 2000.
4.
Population légale 2010 Martinique, INSEE Antilles-Guyane. 2013;(92).
5.
Rouzier R, Mir O, Uzan C, Delaloge S, Barranger E, Descamps P. Prise en charge des cancers du sein en cours de grossesse. 2008.
6.
7.
Rouzier R, Legoff S. Cancers et grossesse. EMC - Traité Médecine AKOS. 2006;1(4):1–5.CrossRef
8.
Eibye S, Kjær SK, Mellemkjær L. Incidence of pregnancy-associated cancer in Denmark, 1977–2006. Obstet Gynecol. 2013;122(3):608–17.
9.
Grimm D, Woelber L, Trillsch F, Keller-v Amsberg G, Mahner S. Clinical management of epithelial ovarian cancer during pregnancy. Eur J Cancer Oxf Engl 1990. 2014;50(5):963–71.
10.
Van Calsteren K, Heyns L, De Smet F, Van Eycken L, Gziri MM, Van Gemert W, et al. Cancer during pregnancy: an analysis of 215 patients emphasizing the obstetrical and the neonatal outcomes. J Clin Oncol Off J Am Soc Clin Oncol. 2010;28(4):683–9.CrossRef
11.
12.
Kwon Y-S, Mok J-E, Lim K-T, Lee I-H, Kim T-J, Lee K-H, et al. Ovarian cancer during pregnancy: clinical and pregnancy outcome. J Korean Med Sci. 2010;25(2):230–4.CrossRefPubMedPubMedCentral
13.
Han SN, Kesic VI, Van Calsteren K, Petkovic S, Amant F. Cancer in pregnancy: a survey of current clinical practice. Eur J Obstet Gynecol Reprod Biol. 2013;167(1):18–23.CrossRefPubMed
14.
Kirby T. Frédéric Amant: leading the agenda on cancer in pregnancy. Lancet Lond Engl. 2012;379(9815):511.CrossRef
15.
Dawood R, Instone M, Kehoe S. Neo-adjuvant chemotherapy for cervical cancer in pregnancy: a case report and literature review. Eur J Obstet Gynecol Reprod Biol. 2013;171(2):205–8.CrossRefPubMed
16.
Fruscio R, Villa A, Chiari S, Vergani P, Ceppi L, Dell’Orto F, et al. Delivery delay with neoadjuvant chemotherapy for cervical cancer patients during pregnancy: a series of nine cases and literature review. Gynecol Oncol. 2012;126(2):192–7.CrossRefPubMed
17.
Cardonick E, Dougherty R, Grana G, Gilmandyar D, Ghaffar S, Usmani A. Breast cancer during pregnancy: maternal and fetal outcomes. Cancer J Sudbury Mass. 2010;16(1):76–82.CrossRef
18.
Amant F, Han SN, Gziri MM, Vandenbroucke T, Verheecke M, Van Calsteren K. Management of cancer in pregnancy. Best Pract Res Clin Obstet Gynaecol. 2015;
19.
Amant F, Deckers S, Van Calsteren K, Loibl S, Halaska M, Brepoels L, et al. Breast cancer in pregnancy: recommendations of an international consensus meeting. Eur J Cancer Oxf Engl 1990. 2010;46(18):3158–68.
20.
Morice P, Narducci F, Mathevet P, Marret H, Darai E, Querleu D, et al. French recommendations on the management of invasive cervical cancer during pregnancy. Int J Gynecol Cancer Off J Int Gynecol Cancer Soc. 2009;19(9):1638–41.CrossRef
21.
Ferrere R, Wendland J. Lorsque maternité et cancer se rencontrent : influence réciproque de deux processus antagonistes. Psycho-Oncol. 2013;7(3):163–8.CrossRef
22.
Dimitrakakis C, Zagouri F, Tsigginou A, Marinopoulos S, Sergentanis TN, Keramopoulos A, et al. Does Pregnancy-Associated Breast Cancer Imply a Worse Prognosis? A Matched Case-Case Study. Breast Care. 2013;8(3):203–7.CrossRefPubMedPubMedCentral
23.
Byrom L, Olsen C, Knight L, Khosrotehrani K, Green AC. Increased mortality for pregnancy-associated melanoma: systematic review and meta-analysis. J Eur Acad Dermatol Venereol JEADV. 2015.
24.
Rodriguez AO, Chew H, Cress R, Xing G, McElvy S, Danielsen B, et al. Evidence of poorer survival in pregnancy-associated breast cancer. Obstet Gynecol. 2008;112(1):71–8.CrossRefPubMed
25.
Halaska MJ, Pentheroudakis G, Strnad P, Stankusova H, Chod J, Robova H, et al. Presentation, management and outcome of 32 patients with pregnancy-associated breast cancer: a matched controlled study. Breast J. 2009;15(5):461–7.CrossRefPubMed
26.
Borja de Mozota D, Kadhel P, Dermeche S, Multigner L, Janky E. Multiple myeloma and pregnancy: a case report and literature review. Arch Gynecol Obstet. 2011;284(4):945–50.CrossRefPubMed
27.
Torres A, Rosa ER, Méndez K, Menéndez A, Romaguera J. Cervical dysplasia and pre-term birth in San Juan city hospital: a cohort retrospective study. Bol Asoc Médica P R. 2013;105(2):36–8.
Metadata
Title
Pregnancy-associated-cancer in the French West Indies (Martinique): maternal and neonatal outcomes
Authors
Kathleen Melan
Jean-Luc Volumenie
Gaël Wan-Ajouhu
Stephen Ulric-Gervaise
Jacqueline Veronique-Baudin
Clarisse Joachim
Publication date
01-12-2017
Publisher
BioMed Central
Published in
BMC Pregnancy and Childbirth / Issue 1/2017
Electronic ISSN: 1471-2393
DOI
https://doi.org/10.1186/s12884-017-1524-0

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