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01-02-2015 | Original Article

Prediction of pancreatic anastomotic failure after pancreatic head resection using preoperative diffusion-weighted MR imaging

Authors: Noriyuki Miyamoto, Satoshi Yabusaki, Keita Sakamoto, Yasuka Kikuchi, Rie Mimura, Fumi Kato, Noriko Oyama-Manabe, Bunya Takahashi, Takeshi Soyama, Daisuke Abo, Yusuke Sakuhara, Kohsuke Kudo, Hiroki Shirato, Toru Nakamura, Takahiro Tsuchikawa, Keisuke Okamura, Satoshi Hirano

Published in: Japanese Journal of Radiology | Issue 2/2015

Abstract

Purpose

To determine whether the preoperative pancreatic apparent diffusion coefficient (ADC) can be used to predict the development of postoperative pancreatic anastomotic failure (PAF).

Materials and methods

We retrospectively examined the cases of 79 patients who underwent pancreatic head resection between January 2010 and October 2013. The patients underwent 1.5-T MR imaging including diffusion-weighted imaging before surgery. The main pancreatic duct diameter (MPD), the pancreatic parenchymal thickness (PT), and the ADC of the pancreatic remnant parenchyma were measured. Two radiologists blinded to the patients’ outcomes performed the measurements. The imaging parameters were compared between the patients who developed PAF and those who did not. The cut-off ADC for the development of PAF was calculated with a receiver operating characteristic analysis.

Results

The imaging parameters were highly correlated between the two observers. The MPD and PT did not differ significantly among the patients. The mean pancreatic ADCs were significantly higher in the patients with PAF than in those without PAF. An ADC higher than 1.50 × 10⁻³ mm²/s (Az = 0.719, observer-1) or 1.35 × 10⁻³ mm²/s (Az = 0.752, observer-2) was optimal for predicting the development of postoperative PAF.

Conclusion

Measuring the preoperative non-tumorous pancreatic ADC may be useful for the prediction of a postoperative PAF.

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Title: Prediction of pancreatic anastomotic failure after pancreatic head resection using preoperative diffusion-weighted MR imaging
Authors: Noriyuki Miyamoto
Satoshi Yabusaki
Keita Sakamoto
Yasuka Kikuchi
Rie Mimura
Fumi Kato
Noriko Oyama-Manabe
Bunya Takahashi
Takeshi Soyama
Daisuke Abo
Yusuke Sakuhara
Kohsuke Kudo
Hiroki Shirato
Toru Nakamura
Takahiro Tsuchikawa
Keisuke Okamura
Satoshi Hirano
Publication date: 01-02-2015
Publisher: Springer Japan
Published in: Japanese Journal of Radiology / Issue 2/2015
Print ISSN: 1867-1071
Electronic ISSN: 1867-108X
DOI: https://doi.org/10.1007/s11604-014-0377-y

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Prediction of pancreatic anastomotic failure after pancreatic head resection using preoperative diffusion-weighted MR imaging

Abstract

Purpose

Materials and methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Materials and methods

Results

Conclusion

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