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Clinical Autonomic Research

Published in:

01-08-2015 | Research article

Prediction of compensatory hyperhidrosis with botulinum toxin A and local anesthetic

Authors: Jin Yong Jeong, Soo Seog Park, Sung Bo Sim, Keon Hyon Jo, Jongho Lee, Saecheol Oh, Jae Seong Shin

Published in: Clinical Autonomic Research | Issue 4/2015

Abstract

Objective

Compensatory hyperhidrosis (CH) is one of the most problematic complications of sympathectomy, which occurs often and is hard to treat. A predictive procedure (PP) for CH can help patients experience compensatory sweating before sympathectomy to determine whether or not to perform sympathectomy. Our study aimed to evaluate the CH after the PP and sympathectomy in patients with primary palmar hyperhidrosis using multiple drugs.

Methods

We reviewed 83 patients who underwent a PP between July 2009 and August 2013 with primary palmar hyperhidrosis. In group A, we used levobupivacaine (n = 39). In group B, we used botulinum toxin A plus ropivacaine for the PP in group B (n = 44).

Results

The CH rate after the PP was 44 % (group A) and 25 % (group B), and after sympathectomy 80 % (group A) and 75 % (group B). The prediction value between the PP and the sympathectomy was statistically significant in group A (p < 0.05). The positive prediction rate was 73 % and the negative prediction rate was 27 % in group A.

Conclusions

Local anesthetic alone has a better predictive value. From our finding, patients should be made aware that CH after sympathectomy is less severe in 73 % of cases than that experienced in the PP.

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Title: Prediction of compensatory hyperhidrosis with botulinum toxin A and local anesthetic
Authors: Jin Yong Jeong
Soo Seog Park
Sung Bo Sim
Keon Hyon Jo
Jongho Lee
Saecheol Oh
Jae Seong Shin
Publication date: 01-08-2015
Publisher: Springer Berlin Heidelberg
Published in: Clinical Autonomic Research / Issue 4/2015
Print ISSN: 0959-9851
Electronic ISSN: 1619-1560
DOI: https://doi.org/10.1007/s10286-015-0288-8

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Prediction of compensatory hyperhidrosis with botulinum toxin A and local anesthetic

Abstract

Objective

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objective

Methods

Results

Conclusions

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