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Open Access 01-12-2016 | Review

Predicting, preventing, and identifying delirium after cardiac surgery

Authors: Jason B. O’Neal, Andrew D. Shaw

Published in: Perioperative Medicine | Issue 1/2016

Abstract

Delirium after cardiac surgery is a major problem. The exact mechanisms behind delirium are not understood. Potential pathways of delirium include neurotransmitter interference, global cognitive disorder, and neuroinflammation. Several predisposing and precipitating risk factors have been identified for postoperative delirium. The development of delirium following cardiac surgery is associated with worse outcomes in the perioperative period. Multiple interventions are being explored for the prevention and treatment of delirium. Studies investigating the potential roles of biomarkers in delirium as well as pharmacological interventions to reduce the incidence and duration of delirium are necessary to mitigate this negative outcome.

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Title: Predicting, preventing, and identifying delirium after cardiac surgery
Authors: Jason B. O’Neal
Andrew D. Shaw
Publication date: 01-12-2016
Publisher: BioMed Central
Published in: Perioperative Medicine / Issue 1/2016
Electronic ISSN: 2047-0525
DOI: https://doi.org/10.1186/s13741-016-0032-5

At a glance: The STEP trials

Springer Medicine

Predicting, preventing, and identifying delirium after cardiac surgery

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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