Skip to main content
Top
Published in: Maternal and Child Health Journal 11/2015

01-11-2015

Predicting Preterm Birth Among Women Screened by North Carolina’s Pregnancy Medical Home Program

Authors: Christine M. Tucker, Kate Berrien, M. Kathryn Menard, Amy H. Herring, Julie Daniels, Diane L. Rowley, Carolyn Tucker Halpern

Published in: Maternal and Child Health Journal | Issue 11/2015

Login to get access

Abstract

Objective

To determine which combination of risk factors from Community Care of North Carolina’s (CCNC) Pregnancy Medical Home (PMH) risk screening form was most predictive of preterm birth (PTB) by parity and race/ethnicity.

Methods

This retrospective cohort included pregnant Medicaid patients screened by the PMH program before 24 weeks gestation who delivered a live birth in North Carolina between September 2011–September 2012 (N = 15,428). Data came from CCNC’s Case Management Information System, Medicaid claims, and birth certificates. Logistic regression with backward stepwise elimination was used to arrive at the final models. To internally validate the predictive model, we used bootstrapping techniques.

Results

The prevalence of PTB was 11 %. Multifetal gestation, a previous PTB, cervical insufficiency, diabetes, renal disease, and hypertension were the strongest risk factors with odds ratios ranging from 2.34 to 10.78. Non-Hispanic black race, underweight, smoking during pregnancy, asthma, other chronic conditions, nulliparity, and a history of a low birth weight infant or fetal death/second trimester loss were additional predictors in the final predictive model. About half of the risk factors prioritized by the PMH program remained in our final model (ROC = 0.66). The odds of PTB associated with food insecurity and obesity differed by parity. The influence of unsafe or unstable housing and short interpregnancy interval on PTB differed by race/ethnicity.

Conclusions

Evaluation of the PMH risk screen provides insight to ensure women at highest risk are prioritized for care management. Using multiple data sources, salient risk factors for PTB were identified, allowing for better-targeted approaches for PTB prevention.
Appendix
Available only for authorised users
Literature
1.
go back to reference Behrman, R. E., & Butler, A. S. (2007). Preterm birth: Causes, consequences, and prevention. Washington, DC: National Academy Press. Behrman, R. E., & Butler, A. S. (2007). Preterm birth: Causes, consequences, and prevention. Washington, DC: National Academy Press.
2.
go back to reference Martin, J. A., Hamilton, B. E., & Osterman, M. J. (2014). Births in the United States, 2013. NCHS data brief, 175, 1–8. Martin, J. A., Hamilton, B. E., & Osterman, M. J. (2014). Births in the United States, 2013. NCHS data brief, 175, 1–8.
7.
go back to reference McCoy, C. (2014). State Title V Program approaches to improving birth outcomes: Lowering non-medically indicated deliveries. McCoy, C. (2014). State Title V Program approaches to improving birth outcomes: Lowering non-medically indicated deliveries.
8.
go back to reference AHRQ. (2013) Statewide Medical Home Program for low-income pregnant women enhances access to comprehensive prenatal care and case management, improves outcomes. AHRQ Healthcare Innovations Exchange. AHRQ. (2013) Statewide Medical Home Program for low-income pregnant women enhances access to comprehensive prenatal care and case management, improves outcomes. AHRQ Healthcare Innovations Exchange.
9.
10.
go back to reference Callaghan, W. M., & Dietz, P. M. (2010). Differences in birth weight for gestational age distributions according to the measures used to assign gestational age. American Journal of Epidemiology, 171(7), 826–836. doi:10.1093/aje/kwp468.CrossRefPubMed Callaghan, W. M., & Dietz, P. M. (2010). Differences in birth weight for gestational age distributions according to the measures used to assign gestational age. American Journal of Epidemiology, 171(7), 826–836. doi:10.​1093/​aje/​kwp468.CrossRefPubMed
13.
14.
go back to reference Taffel, S. (1982). A method of imputing length of gestation on birth certificates. Vital and health statistics. Series 2. Data evaluation and Methods Research (93), 1–11. Taffel, S. (1982). A method of imputing length of gestation on birth certificates. Vital and health statistics. Series 2. Data evaluation and Methods Research (93), 1–11.
15.
go back to reference Efron, B., & Tibshirani, R. J. (1994). An introduction to the bootstrap. London: Chapman & Hall/CRC. Efron, B., & Tibshirani, R. J. (1994). An introduction to the bootstrap. London: Chapman & Hall/CRC.
16.
go back to reference Harrell, F. E. (1996). Multivariable prognostic models: Issues in developing models, evaluating assumptions and adequacy, and measuring and reducing errors. Statistics in Medicine, 15(4), 361–387.CrossRefPubMed Harrell, F. E. (1996). Multivariable prognostic models: Issues in developing models, evaluating assumptions and adequacy, and measuring and reducing errors. Statistics in Medicine, 15(4), 361–387.CrossRefPubMed
17.
go back to reference Steyerberg, E. W., Harrell, F. E, Jr, Borsboom, G. J. J. M., et al. (2001). Internal validation of predictive models: Efficiency of some procedures for logistic regression analysis. Journal of Clinical Epidemiology, 54(8), 774–781. doi:10.1016/s0895-4356(01)00341-9.CrossRefPubMed Steyerberg, E. W., Harrell, F. E, Jr, Borsboom, G. J. J. M., et al. (2001). Internal validation of predictive models: Efficiency of some procedures for logistic regression analysis. Journal of Clinical Epidemiology, 54(8), 774–781. doi:10.​1016/​s0895-4356(01)00341-9.CrossRefPubMed
18.
go back to reference Beta, J. (2011). Prediction of spontaneous preterm delivery from maternal factors, obstetric history and placental perfusion and function at 11–13 weeks. Prenatal Diagnosis, 31(1), 75–83. doi:10.1002/pd.2662.CrossRefPubMed Beta, J. (2011). Prediction of spontaneous preterm delivery from maternal factors, obstetric history and placental perfusion and function at 11–13 weeks. Prenatal Diagnosis, 31(1), 75–83. doi:10.​1002/​pd.​2662.CrossRefPubMed
19.
go back to reference Creasy, R. K. (1980). System for predicting spontaneous preterm birth. Obstetrics and Gynecology (New York, 1953), 55(6), 692–695. Creasy, R. K. (1980). System for predicting spontaneous preterm birth. Obstetrics and Gynecology (New York, 1953), 55(6), 692–695.
20.
go back to reference Edenfield, S. M. (1995). Validity of the Creasy risk appraisal instrument for prediction of preterm labor. Nursing Research (New York), 44(2), 76–81. Edenfield, S. M. (1995). Validity of the Creasy risk appraisal instrument for prediction of preterm labor. Nursing Research (New York), 44(2), 76–81.
22.
go back to reference Owen, J. (1990). Evaluation of a risk scoring system as a predictor of preterm birth in an indigent population. American Journal of Obstetrics and Gynecology, 163(3), 873–879.CrossRefPubMed Owen, J. (1990). Evaluation of a risk scoring system as a predictor of preterm birth in an indigent population. American Journal of Obstetrics and Gynecology, 163(3), 873–879.CrossRefPubMed
23.
go back to reference Tan, H., Wen, S. W., Chen, X. K., et al. (2007). Early prediction of preterm birth for singleton, twin, and triplet pregnancies. European Journal of Obstetrics & Gynecology and Reproductive Biology., 131(2), 132–137. doi:10.1016/j.ejogrb.2006.04.038.CrossRef Tan, H., Wen, S. W., Chen, X. K., et al. (2007). Early prediction of preterm birth for singleton, twin, and triplet pregnancies. European Journal of Obstetrics & Gynecology and Reproductive Biology., 131(2), 132–137. doi:10.​1016/​j.​ejogrb.​2006.​04.​038.CrossRef
24.
go back to reference To, M. S. (2006). Prediction of patient-specific risk of early preterm delivery using maternal history and sonographic measurement of cervical length: A population-based prospective study. Ultrasound in Obstetrics and Gynecology, 27(4), 362–367. doi:10.1002/uog.2773.CrossRefPubMed To, M. S. (2006). Prediction of patient-specific risk of early preterm delivery using maternal history and sonographic measurement of cervical length: A population-based prospective study. Ultrasound in Obstetrics and Gynecology, 27(4), 362–367. doi:10.​1002/​uog.​2773.CrossRefPubMed
26.
go back to reference Baeten, J. M. (2001). Pregnancy complications and outcomes among overweight and obese nulliparous women. American Journal of Public Health, 91(3), 436–440.PubMedCentralCrossRefPubMed Baeten, J. M. (2001). Pregnancy complications and outcomes among overweight and obese nulliparous women. American Journal of Public Health, 91(3), 436–440.PubMedCentralCrossRefPubMed
31.
go back to reference Nabukera, S., Wingate, M., Owen, J., et al. (2009). Racial disparities in perinatal outcomes and pregnancy spacing among women delaying initiation of childbearing. Maternal and Child Health Journal, 13(1), 81–89. doi:10.1007/s10995-008-0330-8.CrossRefPubMed Nabukera, S., Wingate, M., Owen, J., et al. (2009). Racial disparities in perinatal outcomes and pregnancy spacing among women delaying initiation of childbearing. Maternal and Child Health Journal, 13(1), 81–89. doi:10.​1007/​s10995-008-0330-8.CrossRefPubMed
32.
33.
go back to reference Geronimus, A. T. (1992). The weathering hypothesis and the health of African-American women and infants: Evidence and speculations. Ethnicity and Disease, 2(3), 207–221.PubMed Geronimus, A. T. (1992). The weathering hypothesis and the health of African-American women and infants: Evidence and speculations. Ethnicity and Disease, 2(3), 207–221.PubMed
34.
go back to reference Lu, M. C., & Halfon, N. (2003). Racial and ethnic disparities in birth outcomes: A life-course perspective. Maternal and Child Health Journal, 7(1), 13–30.CrossRefPubMed Lu, M. C., & Halfon, N. (2003). Racial and ethnic disparities in birth outcomes: A life-course perspective. Maternal and Child Health Journal, 7(1), 13–30.CrossRefPubMed
37.
go back to reference Klerman, L., Ramey, S., Goldenberg, R., et al. (2001). A randomized trial of augmented prenatal care for multiple-risk, Medicaid-eligible African American women. American Journal of Public Health, 91(1), 105–111.PubMedCentralCrossRefPubMed Klerman, L., Ramey, S., Goldenberg, R., et al. (2001). A randomized trial of augmented prenatal care for multiple-risk, Medicaid-eligible African American women. American Journal of Public Health, 91(1), 105–111.PubMedCentralCrossRefPubMed
38.
go back to reference Willis, W. O. (2004). Lower rates of low birthweight and preterm births in the California Black Infant Health Program. Journal of the National Medical Association, 96(3), 315–324.PubMedCentralPubMed Willis, W. O. (2004). Lower rates of low birthweight and preterm births in the California Black Infant Health Program. Journal of the National Medical Association, 96(3), 315–324.PubMedCentralPubMed
42.
go back to reference Laraia, B. A., Siega-Riz, A. M., Gundersen, C., et al. (2006). Psychosocial factors and socioeconomic indicators are associated with household food insecurity among pregnant women. The Journal of Nutrition, 136(1), 177–182.PubMed Laraia, B. A., Siega-Riz, A. M., Gundersen, C., et al. (2006). Psychosocial factors and socioeconomic indicators are associated with household food insecurity among pregnant women. The Journal of Nutrition, 136(1), 177–182.PubMed
43.
go back to reference Dole, N., Savitz, D. A., Siega-Riz, A. M., et al. (2004). Psychosocial factors and preterm birth among African American and white women in central North Carolina. American Journal of Public Health, 94(8), 1358.PubMedCentralCrossRefPubMed Dole, N., Savitz, D. A., Siega-Riz, A. M., et al. (2004). Psychosocial factors and preterm birth among African American and white women in central North Carolina. American Journal of Public Health, 94(8), 1358.PubMedCentralCrossRefPubMed
44.
go back to reference O’Campo, P., Burke, J. G., Culhane, J., et al. (2008). Neighborhood deprivation and preterm birth among non-Hispanic black and white women in eight geographic areas in the United States. American Journal of Epidemiology, 167(2), 155–163. doi:10.1093/aje/kwm277.CrossRefPubMed O’Campo, P., Burke, J. G., Culhane, J., et al. (2008). Neighborhood deprivation and preterm birth among non-Hispanic black and white women in eight geographic areas in the United States. American Journal of Epidemiology, 167(2), 155–163. doi:10.​1093/​aje/​kwm277.CrossRefPubMed
Metadata
Title
Predicting Preterm Birth Among Women Screened by North Carolina’s Pregnancy Medical Home Program
Authors
Christine M. Tucker
Kate Berrien
M. Kathryn Menard
Amy H. Herring
Julie Daniels
Diane L. Rowley
Carolyn Tucker Halpern
Publication date
01-11-2015
Publisher
Springer US
Published in
Maternal and Child Health Journal / Issue 11/2015
Print ISSN: 1092-7875
Electronic ISSN: 1573-6628
DOI
https://doi.org/10.1007/s10995-015-1763-5

Other articles of this Issue 11/2015

Maternal and Child Health Journal 11/2015 Go to the issue