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Open Access 01-12-2014 | Oral presentation

Preclinical and translational studies of fenobam, an mGlu5 NAM, for the treatment of pain

Authors: Robert W Gereau IV, Laura F Cavallone

Published in: Molecular Pain | Special Issue 1/2014

Excerpt

Metabotropic glutamate receptor 5 has been suggested by many rodent studies to be a promising target for the development of novel analgesic drugs. The lack of approved compounds has prevented proof-of-concept studies in human subjects. Here we describe preclinical and translational studies of the mGlu5 negative allosteric modulator (NAM), fenobam. …

Title: Preclinical and translational studies of fenobam, an mGlu5 NAM, for the treatment of pain
Authors: Robert W Gereau IV
Laura F Cavallone
Publication date: 01-12-2014
Publisher: BioMed Central
Published in: Molecular Pain / Issue Special Issue 1/2014
Electronic ISSN: 1744-8069
DOI: https://doi.org/10.1186/1744-8069-10-S1-O3

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Preclinical and translational studies of fenobam, an mGlu5 NAM, for the treatment of pain

Excerpt

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Excerpt

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