Published in:
Open Access
01-12-2012 | Poster presentation
Pre-contrast T1 mapping for detection of myocardial fibrosis in asymptomatic and symptomatic aortic stenosis
Authors:
Sacha Bull, Steven K White, Stefan K Piechnik, Andrew Flett, Vanessa Ferreira, Margaret Loudon, Jane M Francis, Stefan Neubauer, James Moon, Saul Myerson
Published in:
Journal of Cardiovascular Magnetic Resonance
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Special Issue 1/2012
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Excerpt
Aortic stenosis (AS) leads to diffuse fibrosis in the myocardium which may impair cardiac function. Existing techniques (late gadolinium enhancement [LGE]) are not good at detecting diffuse, as opposed to focal, fibrosis. Pre-contrast T1-mapping may identify changes in the myocardium without the need for exogenous contrast, and our aim was to investigate its ability to detect diffuse fibrosis in patients with AS. …