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Open Access 01-12-2015 | Poster presentation

Pragmatic constraint-led approach to sample size

Authors: Paul Silcocks, Diane Whitham

Published in: Trials | Special Issue 2/2015

Excerpt

Standard approaches to sample size specify power, significance, treatment effect, one-or two-sided test and allocation ratio, to yield the number of patients. Typical reactions are “I can only get 60”. Statisticians often respond by seeing what effect the available number can “buy” for reasonable significance/power. …

Title: Pragmatic constraint-led approach to sample size
Authors: Paul Silcocks
Diane Whitham
Publication date: 01-12-2015
Publisher: BioMed Central
Published in: Trials / Issue Special Issue 2/2015
Electronic ISSN: 1745-6215
DOI: https://doi.org/10.1186/1745-6215-16-S2-P27

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Pragmatic constraint-led approach to sample size

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