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BMC Anesthesiology
Published in: BMC Anesthesiology 1/2024

Open Access 01-12-2024 | Postoperative Nausea and Vomiting | Research

Analysis of influencing factors and construction of prediction model for postoperative nausea and vomiting in patients undergoing laparoscopic sleeve gastrectomy: a single-center retrospective cohort study

Authors: Bucheng Liao, Wuhao Liao, Xinhai Wu, Shujuan Liu, Yanze Li, Ruixia Qin, Shuang Yin

Published in: BMC Anesthesiology | Issue 1/2024

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Abstract

Background

With the increasing number of bariatric surgeries, the high incidence of postoperative nausea and vomiting (PONV) associated with this surgery has also gradually attracted attention. Among the common bariatric surgery methods, patients undergoing sleeve gastrectomy (SG) have the highest incidence of nausea and vomiting. The mechanism of occurrence of PONV is very complex. This study aims to explore the influencing factors of PONV in patients undergoing laparoscopic sleeve gastrectomy (LSG) and construct a nomogram prediction model based on these factors.

Methods

With the approval of the Ethics Committee, the electronic medical records of patients who underwent LSG from July 2022 to May 2023 were collected retrospectively.

Results

A total of 114 patients with complete medical records who underwent LSG from July 2022 to May 2023 were included in this study. Among them, 46 patients developed PONV, resulting in a PONV incidence rate of 40.4%. Multivariate logistic regression analysis revealed that female gender, the use of inhalation anesthesia, and operation time ≥ 120 min were risk factors for PONV in LSG. Additionally, the use of more than two kinds of antiemetic drugs was identified as a protective factor. Based on these factors, a nomogram model was constructed.

Conclusion

PONV in patients undergoing LSG is related to gender, type of anesthesia, duration of surgery, and combination therapy with antiemetic drugs. The nomogram prediction model constructed in this study demonstrates high accuracy and discrimination in predicting the occurrence of PONV in patients undergoing LSG.
Literature
1.
GBD 2015 Obesity Collaborators, Ashkan Afshin, Mohammad H, Forouzanfar, et al. Health effects of overweight and obesity in 195 countries over 25 Years.N Engl. J Med. 2017;377(1):13–27.
2.
Pan X-F, Wang L. An Pan. Epidemiology and determinants of obesity in China. Lancet Diabetes Endocrinol. 2021;9(6):373–92.CrossRefPubMed
3.
Angrisani L, Santonicola A, Iovino P, et al. Bariatric surgery and endoluminal procedures: IFSO Worldwide Survey 2014. Obes Surg. 2017;27(9):2279–89.CrossRefPubMedPubMedCentral
4.
Gimmel PZ, Goldfarb AA, Koppman J et al. Opioid-free total intravenous anaesthesia reduces postoperative nausea and vomiting in bariatric surgery beyondtriple prophylaxis. Br J Anaesth 2014,112:906–11.
5.
Gan T, Kumar G, Belani,Sergio, Bergese et al. Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting.Anesth Analg.2020;131:411 – 48.
6.
Eberhart LHJ, Mauch M, Morin AM, et al. Impact of a multimodal anti-emetic prophylaxis on patient satisfaction in high-risk patients for postoperative nausea and vomiting. Anaesthesia. 2002;57:1022–7.CrossRefPubMed
7.
Myles PS, Williams DL, Hendrata M, et al. Patient satisfaction after anaesthesia and surgery: results of a prospective survey of 10,811 patients.Br. J Anaesth. 2000;84:6–10.CrossRef
8.
Souvik Maitra A, Som, Dalim K, Baidya et al. Comparison of ondansetron and dexamethasone for prophylaxis of postoperative nausea and vomiting in patients undergoing laparoscopic surgeries: a metaanalysis of randomized controlled trials.Anesthesiol Res Pract, 2016, 2016: 7089454.
9.
Celio A, Bayouth L, Burruss MB, et al. Prospective assessment of postoperative nausea early after bariatric surgery. Obes Surg. 2019;29(3):858–61.CrossRefPubMed
10.
Hill RPDA, Lubarsky. B Phillips-Bute,et al.Cost-effectiveness of prophylactic antiemetic kberapy with Ondansetron. Dropeucidolj or Placebo Anesthesiology. 2000;92(4):958–67.CrossRefPubMed
11.
Apfel CC, Heidrich FM, Jukar-Rao S, et al. Evidence-based analysis of risk factors for postoperative nausea and vomiting. Br J Anaesth. 2012;109(5):742–53.CrossRefPubMed
12.
Gan TJ, Diemunsch P, Habib AS, et al. Society for ambulatory anesthesia. Consensus guidelines for the management of postoperative nausea and vomiting. Anesth Analg. 2014;118:85–113.CrossRefPubMed
13.
Horn CC, Wallisch WJ, Homanics GE, Williams JP. Pathophysiological and neurochemical mechanisms of postoperative nausea and vomiting. Eur J Pharmacol. 2014;722:55–66.CrossRefPubMed
14.
Huang J, Lin J, Xiong Y, et al. Risk factors associated with postoperative discomfort after ambulatory strabismus surgery under general anesthesia. J Pain Res. 2020;13:947–53.CrossRefPubMedPubMedCentral
15.
Smith P, Lavery A, Turkington RC et al. Risk factors associated with antineoplastic chemotherapy-induced nausea and vomiting. Rev Saude Publica 2020,54: 106.
16.
Scheiermann P, Herzog F, Siebenhofer A, et al. Intravenous versus inhalational anesthesia for pediatric inpatient surgery - A systematic review and metaanalysis. J Clin Anesth. 2018;49:19–25.CrossRefPubMed
17.
Yang L, Xu YJ, Shen J et al. Propofol-based total intravenous anesthesia decreases the incidence of postoperative nausea and vomiting without affecting flap survival in free flap breast reconstruction.Gland surg,2020,9(5):1406–14.
18.
Schlesinger T, Weibel S, Meybohm P et al. Drugs in anesthesia: preventing postoperative nausea and vomiting.Curr Opin Anaesthesiol. 2021;34(4):421–7.
19.
Zaina Naeem IL, Chen AD, Pryor, et al. Antiemetic Prophylaxis and Anesthetic approaches to reduce postoperative nausea and vomiting in bariatric surgery patients: a systematic review. Obes Surg. 2020;30(8):3188–200.CrossRefPubMed
20.
Peter Kienbaum MS, Schaefer S, Weibel. et al.[Update on PONV-What is new in prophylaxis and treatment of postoperative nausea and vomiting? Summary of recent consensus recommendations and Cochrane reviews on prophylaxis and treatment of postoperative nausea and vomiting].Anaesthesist. 2022;71(2):123–8.
21.
Mohammad F, Mohamed AA, Ayman E. Impact of pyloric injection of Magnesium Sulfate-Lidocaine mixture on postoperative nausea and vomiting after laparoscopic sleeve gastrectomy: a randomized-controlled trial. Obes Surg. 2019;29:1614–23.CrossRef
22.
Yehoshua RT, Eidelman LA, Stein M, et al. Laparoscopic sleeve gastrectomy—volume and pressure assessment. Obes Surg. 2008;18:1083–8.CrossRefPubMed
23.
Gareth J, Sanger J, Broad B, Callaghan et al. Ghrelin and Motilin Control Systems in GI Physiology and Therapeutics.Handb Exp Pharmacol. 2017:239:379–416.
24.
Carlota Tuero V, Valenti F, Rotellar, et al. Revisiting the Ghrelin Changes following bariatric and metabolic Surgery[J]. Obes Surg. 2020;30(7):2763–80.CrossRefPubMed
Metadata
Title
Analysis of influencing factors and construction of prediction model for postoperative nausea and vomiting in patients undergoing laparoscopic sleeve gastrectomy: a single-center retrospective cohort study
Authors
Bucheng Liao
Wuhao Liao
Xinhai Wu
Shujuan Liu
Yanze Li
Ruixia Qin
Shuang Yin
Publication date
01-12-2024
Publisher
BioMed Central
Published in
BMC Anesthesiology / Issue 1/2024
Electronic ISSN: 1471-2253
DOI
https://doi.org/10.1186/s12871-024-02502-z

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