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Canadian Journal of Anesthesia/Journal canadien d'anesthésie
Published in: Canadian Journal of Anesthesia/Journal canadien d'anesthésie 8/2022

13-05-2021 | Postoperative Nausea and Vomiting | Reports of Original Investigations

Preoperative analgesic instruction and prescription reduces early home pain after outpatient surgery: a randomized controlled trial

Authors: Jean Selim, MD, Zoubir Djerada, MD, PhD, Céline Chaventre, MD, Thomas Clavier, MD, PhD, Bertrand Dureuil, MD, PhD, Emmanuel Besnier, MD, PhD, Vincent Compere, MD, PhD

Published in: Canadian Journal of Anesthesia/Journal canadien d'anesthésie | Issue 8/2022

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Abstract

Background

Home pain remains the most common complication in outpatient surgery. Optimal management requires good information and early availability of analgesics. The main objective of this randomized controlled trial was to compare the effects of pre- vs postoperative analgesic instruction and prescription on postoperative home pain.

Methods

Patients were randomized into an anesthesia consultation group (AC group) and a standard postoperative group (POP group). The AC group and the POP group received analgesic prescription and instruction during the anesthesia consultation and after surgery, respectively. The primary outcome was the incidence of home pain on postopertive day one (D1). Home pain was defined by at least one episode with a numeric rating scale score > 3/10 at rest. Treatment compliance and postoperative nausea and vomiting (PONV) were also assessed on D1 and postoperative day 7 (D7).

Results

One hundred and eighty-six patients were included between May 2017 and May 2018 at Rouen University Hospital, France. Ninety-four patients were randomized to the AC group and 92 to the POP group. On D1, the incidence of pain was 23/94 (24%) in the AC group and 44/92 (48%) in the POP group (P < 0.001). On D1, the rate of treatment compliance was significantly higher in the AC group than in the POP group (85% vs 69%; P = 0.02). There was no statistically significant difference in the incidence of pain or treatment compliance between groups on D7 or in PONV on D1 and on D7.

Conclusions

Preoperative analgesic instruction and prescription during anesthesia consultation reduces the incidence of early postoperative home pain in outpatient surgery.

Trial registration

www.clinicaltrialsgov (NCT03205189); registered 2 July 2017.
Appendix
Available only for authorised users
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Metadata
Title
Preoperative analgesic instruction and prescription reduces early home pain after outpatient surgery: a randomized controlled trial
Authors
Jean Selim, MD
Zoubir Djerada, MD, PhD
Céline Chaventre, MD
Thomas Clavier, MD, PhD
Bertrand Dureuil, MD, PhD
Emmanuel Besnier, MD, PhD
Vincent Compere, MD, PhD
Publication date
13-05-2021
Publisher
Springer International Publishing
Published in
Canadian Journal of Anesthesia/Journal canadien d'anesthésie / Issue 8/2022
Print ISSN: 0832-610X
Electronic ISSN: 1496-8975
DOI
https://doi.org/10.1007/s12630-021-02023-0

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