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01-12-2016 | Review

Posterior fossa involvement in the diagnosis of adult-onset inherited leukoencephalopathies

Authors: Xavier Ayrignac, Clemence Boutiere, Clarisse Carra-dalliere, Pierre Labauge

Published in: Journal of Neurology | Issue 12/2016

Abstract

Adult-onset genetic leukoencephalopathies are increasingly recognized. They are heterogeneous groups of disorders that commonly have distinct pathologic mechanisms but they share the presence of supratentorial bilateral and symmetric white matter hyperintensities. Although these abnormalities are usually non-specific, some specific MRI findings exist and sometimes help to distinguish these disorders. In this review, our aim is to describe posterior fossa abnormalities seen in the main adult-onset genetic leukoencephalopathies enabling clinicians to perform oriented genetic/metabolic screening.

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Title: Posterior fossa involvement in the diagnosis of adult-onset inherited leukoencephalopathies
Authors: Xavier Ayrignac
Clemence Boutiere
Clarisse Carra-dalliere
Pierre Labauge
Publication date: 01-12-2016
Publisher: Springer Berlin Heidelberg
Published in: Journal of Neurology / Issue 12/2016
Print ISSN: 0340-5354
Electronic ISSN: 1432-1459
DOI: https://doi.org/10.1007/s00415-016-8131-2

At a glance: The STEP trials

Springer Medicine

Posterior fossa involvement in the diagnosis of adult-onset inherited leukoencephalopathies

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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