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Published in: Current Cardiovascular Imaging Reports 11/2023

Open Access 26-09-2023 | Positron Emission Tomography | Review

68Ga-FAPi: Pathways and Diagnosis in Cardiac Imaging

Authors: Cristina Elena Popescu, Paola Ferro, Irene Gotuzzo, Irene Burger, Axel Rominger, Federico Caobelli

Published in: Current Cardiovascular Imaging Reports | Issue 11/2023

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Abstract

Purpose of Review

Myocardial fibrosis is a response to myocardial injury and plays a pivotal role in ventricular remodeling. Different patterns of fibrosis are associated with different disease states, but the presence and amount of fibrosis provide a different impact on prognosis.

Recent Findings

In the latest years, fibroblast activation protein inhibitor (FAPi) positron emission tomography (PET) gain interest for its potential in detecting myocardial fibrosis, in differentiating between active and chronic disease, and in the assessment of disease progression and response to treatment.

Summary

We aim to highlight the most relevant current applications of FAPi PET/CT in cardiovascular imaging, focusing on its applications, advantages, limitations, and to underline future clinical perspective.
Literature
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Metadata
Title
68Ga-FAPi: Pathways and Diagnosis in Cardiac Imaging
Authors
Cristina Elena Popescu
Paola Ferro
Irene Gotuzzo
Irene Burger
Axel Rominger
Federico Caobelli
Publication date
26-09-2023
Publisher
Springer US
Published in
Current Cardiovascular Imaging Reports / Issue 11/2023
Print ISSN: 1941-9066
Electronic ISSN: 1941-9074
DOI
https://doi.org/10.1007/s12410-023-09583-3