Published in:
Open Access
01-12-2014 | Case report
Positivity to p-ANCA in patients with status epilepticus
Authors:
Edoardo Ferlazzo, Antonio Gambardella, Marina Bellavia, Sara Gasparini, Laura Mumoli, Angelo Labate, Vittoria Cianci, Concetta Russo, Umberto Aguglia
Published in:
BMC Neurology
|
Issue 1/2014
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Abstract
Background
Status epilepticus (SE) may occur in the setting of several internal or neurologic diseases. Anti-neutrophilic cytoplasmic antibodies (ANCA) are a group of Ig that may be observed in patients with different autoimmune disorders but are particularly associated with systemic vasculitis named ANCA-associated-vasculities (AAV). We herein report 3 patients with SE and positivity to p-ANCA.
Case presentation
One patient had a catastrophic evolution and died 5 months after disease onset. The other two patients had a good outcome and remained seizure-free at 30 months and 5 years of follow-up respectively.
Conclusion
This report highlights the importance of considering ANCA dosage in patients with SE of unclear origin.