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Published in: Critical Care 1/2018

Open Access 01-12-2018 | Viewpoint

Position of draining venous cannula in extracorporeal membrane oxygenation for respiratory and respiratory/circulatory support in adult patients

Authors: B. Frenckner, M. Broman, M. Broomé

Published in: Critical Care | Issue 1/2018

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Abstract

Extracorporeal membrane oxygenation (ECMO) is used in critically ill patients with severe pulmonary and/or cardiac failure. Blood is drained from the venous system and pumped through a membrane oxygenator where it is oxygenated. For pulmonary support, the blood is returned to the patient via a vein (veno-venous ECMO) and for pulmonary/circulatory support it is returned via an artery (veno-arterial ECMO).
Veno-venous ECMO can be performed either with a single dual-lumen cannula or with two separate single-lumen cannulas. If the latter is chosen, flow direction can either be from the inferior caval vein (IVC) to the right atrium or the opposite. Earlier research has shown that drainage from the IVC yields less recirculation and therefore the IVC to right atrium route has become the standard in most centers for veno-venous ECMO with two cannulas. However, recent research has shown that recirculation can be minimized using a multistage draining cannula in the optimal position inserted via the right internal jugular vein and with blood return to the femoral vein. The clinical results with this route are excellent.
In veno-arterial ECMO the most common site for blood infusion is the femoral artery. If venous blood is drained from the IVC, the patient is at risk of developing a dual circulation (Harlequin syndrome, North-South syndrome, differential oxygenation) meaning a poor oxygenation of the upper part of the body, while the lower part has excellent oxygenation. By instead draining from the superior caval vein (SVC) via a multistage cannula inserted in the right internal jugular vein this risk is neutralized.
In conclusion, the authors argue that draining blood from the SVC and right atrium via a multistage cannula inserted in the right internal jugular vein is equal or better than IVC drainage both in veno-venous two cannula ECMO and in veno-arterial ECMO with blood return to the femoral artery.
Literature
1.
go back to reference UK collaborative randomised trial of neonatal extracorporeal membrane oxygenation. UK collaborative ECMO Trail group. Lancet. 1996;348(9020):75–82.CrossRef UK collaborative randomised trial of neonatal extracorporeal membrane oxygenation. UK collaborative ECMO Trail group. Lancet. 1996;348(9020):75–82.CrossRef
2.
go back to reference Bartlett RH, Roloff DW, Cornell RG, Andrews AF, Dillon PW, Zwischenberger JB. Extracorporeal circulation in neonatal respiratory failure: a prospective randomized study. Pediatrics. 1985;76(4):479–87.PubMed Bartlett RH, Roloff DW, Cornell RG, Andrews AF, Dillon PW, Zwischenberger JB. Extracorporeal circulation in neonatal respiratory failure: a prospective randomized study. Pediatrics. 1985;76(4):479–87.PubMed
3.
go back to reference O'Rourke PP, Crone RK, Vacanti JP, Ware JH, Lillehei CW, Parad RB, Epstein MF. Extracorporeal membrane oxygenation and conventional medical therapy in neonates with persistent pulmonary hypertension of the newborn: a prospective randomized study. Pediatrics. 1989;84(6):957–63.PubMed O'Rourke PP, Crone RK, Vacanti JP, Ware JH, Lillehei CW, Parad RB, Epstein MF. Extracorporeal membrane oxygenation and conventional medical therapy in neonates with persistent pulmonary hypertension of the newborn: a prospective randomized study. Pediatrics. 1989;84(6):957–63.PubMed
4.
go back to reference Peek GJ, Mugford M, Tiruvoipati R, et al. Efficacy and economic assessment of conventional ventilatory support versus extracorporeal membrane oxygenation for severe adult respiratory failure (CESAR): a multicentre randomised controlled trial. Lancet. 2009;374(9698):1351–63.CrossRefPubMed Peek GJ, Mugford M, Tiruvoipati R, et al. Efficacy and economic assessment of conventional ventilatory support versus extracorporeal membrane oxygenation for severe adult respiratory failure (CESAR): a multicentre randomised controlled trial. Lancet. 2009;374(9698):1351–63.CrossRefPubMed
5.
go back to reference Abrams D, Bacchetta M, Brodie D. Recirculation in venovenous extracorporeal membrane oxygenation. ASAIO J. 2015;61(2):115–21.CrossRefPubMed Abrams D, Bacchetta M, Brodie D. Recirculation in venovenous extracorporeal membrane oxygenation. ASAIO J. 2015;61(2):115–21.CrossRefPubMed
6.
go back to reference Kolla S, Awad SS, Rich PB, Schreiner RJ, Hirschl RB, Bartlett RH. Extracorporeal life support for 100 adult patients with severe respiratory failure. Ann Surg. 1997;226(4):544–64. discussion 65-6CrossRefPubMedPubMedCentral Kolla S, Awad SS, Rich PB, Schreiner RJ, Hirschl RB, Bartlett RH. Extracorporeal life support for 100 adult patients with severe respiratory failure. Ann Surg. 1997;226(4):544–64. discussion 65-6CrossRefPubMedPubMedCentral
7.
go back to reference Lewandowski K, Rossaint R, Pappert D, et al. High survival rate in 122 ARDS patients managed according to a clinical algorithm including extracorporeal membrane oxygenation. Intensive Care Med. 1997;23(8):819–35.CrossRefPubMed Lewandowski K, Rossaint R, Pappert D, et al. High survival rate in 122 ARDS patients managed according to a clinical algorithm including extracorporeal membrane oxygenation. Intensive Care Med. 1997;23(8):819–35.CrossRefPubMed
8.
go back to reference Rich PB, Awad SS, Crotti S, Hirschl RB, Bartlett RH, Schreiner RJ. A prospective comparison of atrio-femoral and femoro-atrial flow in adult venovenous extracorporeal life support. J Thorac Cardiovasc Surg. 1998;116(4):628–32.CrossRefPubMed Rich PB, Awad SS, Crotti S, Hirschl RB, Bartlett RH, Schreiner RJ. A prospective comparison of atrio-femoral and femoro-atrial flow in adult venovenous extracorporeal life support. J Thorac Cardiovasc Surg. 1998;116(4):628–32.CrossRefPubMed
9.
go back to reference Lynch W. ECLS Cannulation for adults with respiratory failure. In: Brogan TV, Lequier L, Lorusso R, MacLaren G, Peek G, editors. Extracorporeal life support: the ELSO red book. 5 edn. Ann Arbor,: Extracorporeal life support organization; 2017. p. 429–437. Lynch W. ECLS Cannulation for adults with respiratory failure. In: Brogan TV, Lequier L, Lorusso R, MacLaren G, Peek G, editors. Extracorporeal life support: the ELSO red book. 5 edn. Ann Arbor,: Extracorporeal life support organization; 2017. p. 429–437.
10.
go back to reference Palmer O, Palmer K, Hultman J, Broman M. Cannula design and recirculation during venovenous extracorporeal membrane oxygenation. ASAIO J. 2016;62(6):737–42.CrossRefPubMedPubMedCentral Palmer O, Palmer K, Hultman J, Broman M. Cannula design and recirculation during venovenous extracorporeal membrane oxygenation. ASAIO J. 2016;62(6):737–42.CrossRefPubMedPubMedCentral
11.
go back to reference von Bahr V, Hultman J, Eksborg S, Frenckner B, Kalzen H. Long-term survival in adults treated with extracorporeal membrane oxygenation for respiratory failure and sepsis. Crit Care Med. 2017;45(2):164–70.CrossRefPubMed von Bahr V, Hultman J, Eksborg S, Frenckner B, Kalzen H. Long-term survival in adults treated with extracorporeal membrane oxygenation for respiratory failure and sepsis. Crit Care Med. 2017;45(2):164–70.CrossRefPubMed
12.
go back to reference Kitamura M, Shibuya M, Kurihara H, Akimoto T, Endo M, Koyanagi H. Effective cross-circulation technique of venoarterial bypass for differential hypoxia condition. Artif Organs. 1997;21(7):786–8.CrossRefPubMed Kitamura M, Shibuya M, Kurihara H, Akimoto T, Endo M, Koyanagi H. Effective cross-circulation technique of venoarterial bypass for differential hypoxia condition. Artif Organs. 1997;21(7):786–8.CrossRefPubMed
13.
go back to reference Hou X, Yang X, Du Z, et al. Superior vena cava drainage improves upper body oxygenation during veno-arterial extracorporeal membrane oxygenation in sheep. Crit Care. 2015;19:68.CrossRefPubMedPubMedCentral Hou X, Yang X, Du Z, et al. Superior vena cava drainage improves upper body oxygenation during veno-arterial extracorporeal membrane oxygenation in sheep. Crit Care. 2015;19:68.CrossRefPubMedPubMedCentral
14.
go back to reference Lindfors M, Frenckner B, Sartipy U, Bjallmark A, Broome M. Venous cannula positioning in arterial deoxygenation during veno-arterial extracorporeal membrane oxygenation—a simulation study and case report. Artif Organs. 2017;41(1):75–81.CrossRefPubMed Lindfors M, Frenckner B, Sartipy U, Bjallmark A, Broome M. Venous cannula positioning in arterial deoxygenation during veno-arterial extracorporeal membrane oxygenation—a simulation study and case report. Artif Organs. 2017;41(1):75–81.CrossRefPubMed
15.
go back to reference Werner NL, Coughlin M, Cooley E, Haft JW, Hirschl RB, Bartlett RH, Mychaliska GB. The University of Michigan experience with veno-venoarterial hybrid mode of extracorporeal membrane oxygenation. ASAIO J. 2016;62(5):578–83.CrossRefPubMed Werner NL, Coughlin M, Cooley E, Haft JW, Hirschl RB, Bartlett RH, Mychaliska GB. The University of Michigan experience with veno-venoarterial hybrid mode of extracorporeal membrane oxygenation. ASAIO J. 2016;62(5):578–83.CrossRefPubMed
16.
go back to reference Hussain ST, Navia JL. Cannulation for ECMO in adult patients with cardiac failure. In: Brogan TV, Lequier L, Lorusso R, MacLaren G, Peek G, editors. Extracorporeal life support: the ELSO red book. Ann Arbor: Extracorporeal life support organization; 2017. p. 523–31. Hussain ST, Navia JL. Cannulation for ECMO in adult patients with cardiac failure. In: Brogan TV, Lequier L, Lorusso R, MacLaren G, Peek G, editors. Extracorporeal life support: the ELSO red book. Ann Arbor: Extracorporeal life support organization; 2017. p. 523–31.
17.
Metadata
Title
Position of draining venous cannula in extracorporeal membrane oxygenation for respiratory and respiratory/circulatory support in adult patients
Authors
B. Frenckner
M. Broman
M. Broomé
Publication date
01-12-2018
Publisher
BioMed Central
Published in
Critical Care / Issue 1/2018
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/s13054-018-2083-0

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