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Published in: Indian Journal of Gastroenterology 5/2015

01-09-2015 | Review Article

Portal hypertensive gastropathy and gastric antral vascular ectasia

Authors: Hitendra Garg, Subhash Gupta, A C. Anand, S. L. Broor

Published in: Indian Journal of Gastroenterology | Issue 5/2015

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Abstract

Portal hypertensive gastropathy (PHG) and gastric antral vascular ectasia (GAVE) are gastric mucosal lesions that mostly present as chronic anemia and rarely cause the acute gastrointestinal hemorrhage. Despite similar clinical manifestations, their pathophysiology and management are entirely different. PHG is seen exclusively in patients with portal hypertension, but GAVE can also be observed in patients with other conditions. Their diagnosis is endoscopic, and although generally each of them has a characteristic endoscopic appearance and distribution, there are cases in which the differential is difficult and must rely on histology. This review focuses on the management of both entities. The mainstay of management of PHG is based on portal-hypotensive pharmacological treatment while GAVE benefits from hormonal therapy, endoscopic Nd:YAG laser, and argon plasma coagulation. More invasive options should be reserved for refractory cases.
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Metadata
Title
Portal hypertensive gastropathy and gastric antral vascular ectasia
Authors
Hitendra Garg
Subhash Gupta
A C. Anand
S. L. Broor
Publication date
01-09-2015
Publisher
Springer India
Published in
Indian Journal of Gastroenterology / Issue 5/2015
Print ISSN: 0254-8860
Electronic ISSN: 0975-0711
DOI
https://doi.org/10.1007/s12664-015-0605-0

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