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01-01-2007 | Original Article

Population study and evaluation of 20 Y-chromosome STR loci in Germans

Authors: Heike Rodig, Manja Grum, Hans-Dieter Grimmecke

Published in: International Journal of Legal Medicine | Issue 1/2007

Abstract

The nine European minimal haplotype (EMH) loci, the two SWGDAM loci and five further single-copy Y-chromosomal short tandem repeats (Y-STRs) DYS446, DYS447, DYS448, DYS449, DYS463, and the multicopy loci DYS464 were evaluated in the German population groups Dresden, Hamburg, Rostock, Munich, and the Sorbs who are a Slavic-speaking minority in Lusatia. Highest gene diversities in all populations were shown for DYS464, DYS385, and DYS449 (D=0.8559–0.9486). The haplotype diversity for the European minimal haplotype loci ranged between 0.9852 for Sorbs and 0.9983 for the Hamburg population showing that there is a significant portion of haplotypes which could not be resolved. Advanced typing using DYS446, DYS447, DYS448, DYS449, DYS463, and DYS464 discriminated all non-related individuals of the Dresden, Hamburg, and Rostock populations. Evaluation of the Y-STRs was accomplished by sequence analysis of all allelic fragments of the allelic ladders and microvariant alleles of DYS385 and the determination of the amounts of stutter products of the loci.

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Title: Population study and evaluation of 20 Y-chromosome STR loci in Germans
Authors: Heike Rodig
Manja Grum
Hans-Dieter Grimmecke
Publication date: 01-01-2007
Publisher: Springer-Verlag
Published in: International Journal of Legal Medicine / Issue 1/2007
Print ISSN: 0937-9827
Electronic ISSN: 1437-1596
DOI: https://doi.org/10.1007/s00414-005-0075-5

At a glance: The STEP trials

Springer Medicine

Population study and evaluation of 20 Y-chromosome STR loci in Germans

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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