Skip to main content
Top
Published in: International Journal of Legal Medicine 6/2016

01-11-2016 | Population Data

Population data of 23 STR loci (PowerPlex® Fusion System) in Mexican Mestizos from the West Region

Authors: J. A. Aguilar-Velázquez, G. Martínez-Cortés, A. Inclán-Sánchez, O. Romero-Rentería, X. X. Díaz-Navarro, H. Rangel-Villalobos

Published in: International Journal of Legal Medicine | Issue 6/2016

Login to get access

Abstract

We analyzed 238 unrelated Mestizo (admixed) individuals from the West region of Mexico with the PowerPlex® Fusion System (Promega Corp.). Allele frequencies and forensic parameters were estimated for the 23 STRs included in this kit. Hardy-Weinberg equilibrium by locus and non-association between pair of loci were demonstrated by exact tests in this population. The combined PE and PD offered by this HID kit were ≥0.9999999986, representing a substantial improvement with respect to those previously offered by 15 STR systems. Interpopulation comparison by AMOVA tests demonstrated low but significant differences among Mexican Mestizos from West, Center, and Northeast regions (Fst = 0.01558; p = 0.0000), similar to the observed among three main ethnic groups from USA (Fst = 0.02048; p = 0.0000). This finding is consistent with the contrary clines of European and Amerindian ancestries described throughout the Mexican territory for Mestizos, the largest population (~90 %) in this country.
Appendix
Available only for authorised users
Literature
1.
go back to reference Rubi-Castellanos R, Martinez-Cortes G, Munoz-Valle JF, Gonzalez-Martin A, Cerda-Flores RM, Anaya-Palafox M, Rangel-Villalobos H (2009) Pre-Hispanic Mesoamerican demography approximates the present-day ancestry of Mestizos throughout the territory of Mexico. Am J Phys Anthropol 139(3):284–294CrossRefPubMed Rubi-Castellanos R, Martinez-Cortes G, Munoz-Valle JF, Gonzalez-Martin A, Cerda-Flores RM, Anaya-Palafox M, Rangel-Villalobos H (2009) Pre-Hispanic Mesoamerican demography approximates the present-day ancestry of Mestizos throughout the territory of Mexico. Am J Phys Anthropol 139(3):284–294CrossRefPubMed
2.
go back to reference Oostdik K, Lenz K, Nye J, Schelling K, Yet D, Bruski S, Strong J, Buchanan C, Sutton J, Linner J, Frazier N, Young H, Matthies L, Sage A, Hahn J, Wells R, Williams N, Price M, Koehler J, Staples M, Swango KL, Hill C, Oyerly K, Duke W, Katzilierakis L, Ensenberger MG, Bourdeau JM, Sprecher CJ, Krenke B, Storts DR (2014) Developmental validation of the PowerPlex Fusion system for analysis of casework and reference samples: a 24-locus multiplex for new database standards. Forensic Sci Int Genet 12:69–76CrossRefPubMed Oostdik K, Lenz K, Nye J, Schelling K, Yet D, Bruski S, Strong J, Buchanan C, Sutton J, Linner J, Frazier N, Young H, Matthies L, Sage A, Hahn J, Wells R, Williams N, Price M, Koehler J, Staples M, Swango KL, Hill C, Oyerly K, Duke W, Katzilierakis L, Ensenberger MG, Bourdeau JM, Sprecher CJ, Krenke B, Storts DR (2014) Developmental validation of the PowerPlex Fusion system for analysis of casework and reference samples: a 24-locus multiplex for new database standards. Forensic Sci Int Genet 12:69–76CrossRefPubMed
3.
go back to reference Salazar-Flores J, Zuniga-Chiquette F, Rubi-Castellanos R, Alvarez-Miranda JL, Zetina-Hernandez A, Martinez-Sevilla VM, Gonzalez-Andrade F, Corach D, Vullo C, Alvarez JC, Lorente JA, Sanchez-Diz P, Herrera RJ, Cerda-Flores RM, Munoz-Valle JF, Rangel-Villalobos H (2015) Admixture and genetic relationships of Mexican Mestizos regarding Latin American and Caribbean populations based on 13 CODIS-STRs. Homo : internationale Zeitschrift fur die vergleichende Forschung am Menschen 66(1):44–59CrossRef Salazar-Flores J, Zuniga-Chiquette F, Rubi-Castellanos R, Alvarez-Miranda JL, Zetina-Hernandez A, Martinez-Sevilla VM, Gonzalez-Andrade F, Corach D, Vullo C, Alvarez JC, Lorente JA, Sanchez-Diz P, Herrera RJ, Cerda-Flores RM, Munoz-Valle JF, Rangel-Villalobos H (2015) Admixture and genetic relationships of Mexican Mestizos regarding Latin American and Caribbean populations based on 13 CODIS-STRs. Homo : internationale Zeitschrift fur die vergleichende Forschung am Menschen 66(1):44–59CrossRef
4.
go back to reference Ramírez-Flores E, Saiz M, Villegas-Carmona D, Alvarez-Cubero MJ (2014) Genetic variation of 24 STR loci in a Mexican Mestizo population from Mexico D.F. Forensic Sci Int Genet 10:4–6CrossRef Ramírez-Flores E, Saiz M, Villegas-Carmona D, Alvarez-Cubero MJ (2014) Genetic variation of 24 STR loci in a Mexican Mestizo population from Mexico D.F. Forensic Sci Int Genet 10:4–6CrossRef
5.
go back to reference Ramos-González B, Aguilar-Velázquez JA, Chávez-Briones ML, Delgado-Chavarría JR, Alfaro-Lopez E, Rangel-Villalobos H (2015) Population data of 24 STRs in Mexican-Mestizo population from Monterrey, Nuevo Leon (Northeast, Mexico) based on PowerPlex® Fusion and GlobalFiler® kits. Forensic Sci Int Genet Ramos-González B, Aguilar-Velázquez JA, Chávez-Briones ML, Delgado-Chavarría JR, Alfaro-Lopez E, Rangel-Villalobos H (2015) Population data of 24 STRs in Mexican-Mestizo population from Monterrey, Nuevo Leon (Northeast, Mexico) based on PowerPlex® Fusion and GlobalFiler® kits. Forensic Sci Int Genet
6.
go back to reference Carracedo A, Butler JM, Gusmão L, Linacre A, Parson W, Roewer L, Schneider PM (2013) New guidelines for the publication of genetic population data. Forensic Sci Int Genet 7:217–220CrossRefPubMed Carracedo A, Butler JM, Gusmão L, Linacre A, Parson W, Roewer L, Schneider PM (2013) New guidelines for the publication of genetic population data. Forensic Sci Int Genet 7:217–220CrossRefPubMed
7.
go back to reference Tereba A (1999) Tools for analysis of population statistics. Profiles in DNA Tereba A (1999) Tools for analysis of population statistics. Profiles in DNA
8.
go back to reference The evaluation of Forensic DNA Evidence (1996) National Research Council (NRC) Committee on DNA Forensic Science. National Academic Press, Washington, DC The evaluation of Forensic DNA Evidence (1996) National Research Council (NRC) Committee on DNA Forensic Science. National Academic Press, Washington, DC
9.
go back to reference Lewis PO, Zaykin D (2015) Genetic Data Analysis (GDA): Computer program for the analysis of allelic data v.1.1 Lewis PO, Zaykin D (2015) Genetic Data Analysis (GDA): Computer program for the analysis of allelic data v.1.1
10.
go back to reference Hill CR, Duewer DL, Kline MC, Coble MD, Butler JM (2013) U.S. population data for 29 autosomal STR loci. Forensic Sci Int Genet 7(3):e82–e83CrossRefPubMed Hill CR, Duewer DL, Kline MC, Coble MD, Butler JM (2013) U.S. population data for 29 autosomal STR loci. Forensic Sci Int Genet 7(3):e82–e83CrossRefPubMed
11.
go back to reference Excoffier L, Lischer H (2010) Arlequin suite v.3.5: a new series of programs to perform population genetics analyses under Linux and Windows. Mol Ecol Resour 10(3), 5ed Excoffier L, Lischer H (2010) Arlequin suite v.3.5: a new series of programs to perform population genetics analyses under Linux and Windows. Mol Ecol Resour 10(3), 5ed
12.
go back to reference IBM corp. (2010) IBM SPSS Statistics for Windows. v.19.0. Armonk, NY IBM corp. (2010) IBM SPSS Statistics for Windows. v.19.0. Armonk, NY
Metadata
Title
Population data of 23 STR loci (PowerPlex® Fusion System) in Mexican Mestizos from the West Region
Authors
J. A. Aguilar-Velázquez
G. Martínez-Cortés
A. Inclán-Sánchez
O. Romero-Rentería
X. X. Díaz-Navarro
H. Rangel-Villalobos
Publication date
01-11-2016
Publisher
Springer Berlin Heidelberg
Published in
International Journal of Legal Medicine / Issue 6/2016
Print ISSN: 0937-9827
Electronic ISSN: 1437-1596
DOI
https://doi.org/10.1007/s00414-016-1361-0

Other articles of this Issue 6/2016

International Journal of Legal Medicine 6/2016 Go to the issue