Skip to main content
Top
Published in: International Journal of Legal Medicine 5/2016

01-09-2016 | Population Data

Population data of 17 short tandem repeat loci in 2923 individuals from the Han population of Nantong in East China

Authors: Min Yang, Liming Li, Haijun Han, Li Jin, Dongtao Jia, Shilin Li

Published in: International Journal of Legal Medicine | Issue 5/2016

Login to get access

Abstract

Nantong is located in mid-eastern China, and the Han population in Nantong may be greatly affected by population admixture between northern and southern Han Chinese populations. In this study, we analyzed 17 autosomal short tandem repeat (STR) loci on 2923 unrelated individuals collected from the Han population of Nantong. No significant deviation from Hardy-Weinberg equilibrium was observed at all STR loci, and the expected heterozygosity ranged from 0.6184 to 0.9187. The combined match probability (CMP) was 3.87 × 10−21, and the combined power of discrimination (CPD) was 99.999999999999999999613 %. No significant difference of allele frequencies was observed between Nantong and other Han populations at all STR loci, as well as Dai, Mongolian, and Tibetan. Significant differences were only observed between Nantong Han and Uyghur at TH01, as well as Nantong Han and Dong at CSF1PO and FGA. Nantong Han showed significant differences between She, Bouyei, and Miao at multiple STR loci.
Appendix
Available only for authorised users
Literature
1.
go back to reference Xu SH, Yin XY, Li SL, Jin WF, Lou HY, Yang L, Gong XH, Wang HY, Shen YP, Pan XD, He YG, Yang YJ, Wang Y, Fu WQ, An Y, Wang JC, Tan JZ, Qian J, Chen XL, Zhang X, Sun YF, Zhang XJ, Wu BL, Jin L (2009) Genomic dissection of population substructure of Han Chinese and its implication in association studies. Am J Hum Genet 85(6):762–774. doi:10.1016/j.ajhg.2009.10.015 CrossRef Xu SH, Yin XY, Li SL, Jin WF, Lou HY, Yang L, Gong XH, Wang HY, Shen YP, Pan XD, He YG, Yang YJ, Wang Y, Fu WQ, An Y, Wang JC, Tan JZ, Qian J, Chen XL, Zhang X, Sun YF, Zhang XJ, Wu BL, Jin L (2009) Genomic dissection of population substructure of Han Chinese and its implication in association studies. Am J Hum Genet 85(6):762–774. doi:10.​1016/​j.​ajhg.​2009.​10.​015 CrossRef
2.
go back to reference Fan SL, Shen CM, Wang F, Ma J, Wang HD, Yang G, Qin HX, Xie T, Li SB, Yan JW, Liu Y (2012) Population genetics polymorphisms on 17 autosomal STRs from Chinese Bai ethnic minority group. Forensic Sci Int Genet 6(1):E22–E23. doi:10.1016/j.fsigen.2010.12.014 CrossRef Fan SL, Shen CM, Wang F, Ma J, Wang HD, Yang G, Qin HX, Xie T, Li SB, Yan JW, Liu Y (2012) Population genetics polymorphisms on 17 autosomal STRs from Chinese Bai ethnic minority group. Forensic Sci Int Genet 6(1):E22–E23. doi:10.​1016/​j.​fsigen.​2010.​12.​014 CrossRef
3.
go back to reference Bar W, Brinkmann B, Budowle B, Carracedo A, Gill P, Lincoln P, Mayr W, Olaisen B (1997) DNA recommendations—further report of the DNA commission of the ISFH regarding the use of short tandem repeat systems. Int J Legal Med 110(4):175–176. doi:10.1007/s004140050061 CrossRef Bar W, Brinkmann B, Budowle B, Carracedo A, Gill P, Lincoln P, Mayr W, Olaisen B (1997) DNA recommendations—further report of the DNA commission of the ISFH regarding the use of short tandem repeat systems. Int J Legal Med 110(4):175–176. doi:10.​1007/​s004140050061 CrossRef
6.
go back to reference Zhao F, Wu X, Cai G, Xu C (2003) The application of Modified-Powerstates software in forensic biostatistics (in Chinese). Chin J Forensic Med 18(5):297–298 Zhao F, Wu X, Cai G, Xu C (2003) The application of Modified-Powerstates software in forensic biostatistics (in Chinese). Chin J Forensic Med 18(5):297–298
7.
go back to reference Li L, Xu J, Liu X, Chen W, Xia M, Yang S, Jiang P, Ma T, Yang Y, Qian J, Sun H, Hu R, Miqin, Feng Z, Zuo Y, Zhou R, Ping Y, Zhou H, Zhao Z, Jin L, Li S (2015) Population data of 15 short tandem repeat loci in 1084 individuals from six Han and four ethnic populations in China. Forensic Sci Int Genet 19:146–147. doi:10.1016/j.fsigen.2015.06.015 CrossRef Li L, Xu J, Liu X, Chen W, Xia M, Yang S, Jiang P, Ma T, Yang Y, Qian J, Sun H, Hu R, Miqin, Feng Z, Zuo Y, Zhou R, Ping Y, Zhou H, Zhao Z, Jin L, Li S (2015) Population data of 15 short tandem repeat loci in 1084 individuals from six Han and four ethnic populations in China. Forensic Sci Int Genet 19:146–147. doi:10.​1016/​j.​fsigen.​2015.​06.​015 CrossRef
8.
go back to reference Yuan-Ming Wu X-NZ, Zhou Y, Chen Z-Y, Wang X-B (2008) Genetic polymorphisms of 15 STR loci in Chinese Han population living in Xi’an city of Shaanxi Province. Forensic Sci Int Genet 2:e15–e18CrossRef Yuan-Ming Wu X-NZ, Zhou Y, Chen Z-Y, Wang X-B (2008) Genetic polymorphisms of 15 STR loci in Chinese Han population living in Xi’an city of Shaanxi Province. Forensic Sci Int Genet 2:e15–e18CrossRef
9.
go back to reference Yuning Zhu SL, Xe Z, Chen Y, You J (2009) Genetic analysis of 15 STR loci in the population of Zhejiang Province (Southeast China). Forensic Sci Int Genet Yuning Zhu SL, Xe Z, Chen Y, You J (2009) Genetic analysis of 15 STR loci in the population of Zhejiang Province (Southeast China). Forensic Sci Int Genet
12.
Metadata
Title
Population data of 17 short tandem repeat loci in 2923 individuals from the Han population of Nantong in East China
Authors
Min Yang
Liming Li
Haijun Han
Li Jin
Dongtao Jia
Shilin Li
Publication date
01-09-2016
Publisher
Springer Berlin Heidelberg
Published in
International Journal of Legal Medicine / Issue 5/2016
Print ISSN: 0937-9827
Electronic ISSN: 1437-1596
DOI
https://doi.org/10.1007/s00414-016-1332-5

Other articles of this Issue 5/2016

International Journal of Legal Medicine 5/2016 Go to the issue