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Archives of Gynecology and Obstetrics

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01-08-2014 | Gynecologic Endocrinology and Reproductive Medicine

Polycystic ovarian syndrome and congenital uterine anomalies: the hidden common player

Authors: Hisham Ali Saleh, Fady M. Shawky Moiety

Published in: Archives of Gynecology and Obstetrics | Issue 2/2014

Abstract

Objective

To study the association between polycystic ovary syndrome (PCOS) and congenital uterine (Müllerian) anomalies in infertile patients. The ultimate aim was to check for a common factor linking both reproductive health problems.

Design

A prospective observational study.

Setting

Tertiary referral infertility center.

Subjects and methodology

3,900 infertile patients were included. The diagnoses of PCOS and uterine anomalies were made. Patients with or without PCOS were correlated to the presence or absence of uterine anomalies and statistically assessed.

Main outcome measures

Study of the prevalence of PCOS/uterine anomalies in the studied population and the ratio of coexistence.

Results

The prevalence of PCOS in the studied cohort was 10.48 %. 409 (10.48 %) patients were confirmed to have PCOS, while 204 (5.23 %) were with confirmed uterine anomalies. Of the patients with confirmed PCOS, almost one-third (n = 149, 31.4 %) had uterine anomalies, while in patients with confirmed uterine anomalies, almost three-fourths (n = 149, 73 %) had PCOS.

Conclusions

There is evident association between PCOS and uterine anomalies in infertile patients. We suggest a genetic rather than a developmental defect to be a possible common player for the development of both PCOS and uterine anomalies.

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Title: Polycystic ovarian syndrome and congenital uterine anomalies: the hidden common player
Authors: Hisham Ali Saleh
Fady M. Shawky Moiety
Publication date: 01-08-2014
Publisher: Springer Berlin Heidelberg
Published in: Archives of Gynecology and Obstetrics / Issue 2/2014
Print ISSN: 0932-0067
Electronic ISSN: 1432-0711
DOI: https://doi.org/10.1007/s00404-014-3193-9

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Polycystic ovarian syndrome and congenital uterine anomalies: the hidden common player

Abstract

Objective

Design

Setting

Subjects and methodology

Main outcome measures

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objective

Design

Setting

Subjects and methodology

Main outcome measures

Results

Conclusions

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