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Tumor Biology
Published in: Tumor Biology 9/2014

01-09-2014 | Review

Podoplanin—a novel marker in oral carcinogenesis

Authors: Niharika Swain, Shwetha V. Kumar, Samapika Routray, Jigna Pathak, Shilpa Patel

Published in: Tumor Biology | Issue 9/2014

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Abstract

Podoplanin, a transmembrane sialoglycoprotein, is a specific marker for lymphatic endothelial cells which in recent years has gained prominent notoriety for its role in tumor progression and metastasis. It is an extensively studied biomarker for predictive assessment of malignant transformation as well as biologic behavior in both human precancer and cancer, respectively. This review summarizes the association of podoplanin overexpression in oral potentially malignant disorders and oral cancer with special emphasis on its putative role in carcinogenesis as well as its prospective use in targeted therapy.
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Metadata
Title
Podoplanin—a novel marker in oral carcinogenesis
Authors
Niharika Swain
Shwetha V. Kumar
Samapika Routray
Jigna Pathak
Shilpa Patel
Publication date
01-09-2014
Publisher
Springer Netherlands
Published in
Tumor Biology / Issue 9/2014
Print ISSN: 1010-4283
Electronic ISSN: 1423-0380
DOI
https://doi.org/10.1007/s13277-014-2266-5

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