Skip to main content
Top
Published in: BMC Infectious Diseases 1/2023

Open Access 01-12-2023 | Pleural Effusion | Case report

Pleural effusion caused by Trichinella spiralis infection: two case reports

Authors: Zhen-zhen Pan, Miao-juan Zhu, Yu-qiong Rong, Jiong Yang

Published in: BMC Infectious Diseases | Issue 1/2023

Login to get access

Abstract

Background

Trichinosis is a worldwide food-borne zoonotic parasitic disease, which is mainly obtained by ingesting undercooked meat containing infected larvae. The purpose of our article is to introduce and discuss two rare cases of pleural effusion caused by Trichinella spiralis.

Case presentation

Here we described two male patients who presented to the respiratory department of our hospital with a massive unilateral pleural effusion, their serum eosinophils were in the normal range, laboratory serological tests revealed that Trichinella spiralis IgG antibody was positive. After the oral administration of antiparasitic drugs, the pleural effusion of two patients was completely absorbed.

Conclusion

Both patients were diagnosed with Trichinosis complicated with pleural effusion, which is very rare in the clinic and easy to be misdiagnosed because of normal eosinophils.
Literature
1.
go back to reference Capo V, Despommier DD. Clinical aspects of infection with Trichinella spp. Clin Microbiol Rev. 1996;9(1):47–54.CrossRef Capo V, Despommier DD. Clinical aspects of infection with Trichinella spp. Clin Microbiol Rev. 1996;9(1):47–54.CrossRef
2.
go back to reference Wilson NO, Hall RL, Montgomery SP, Jones JL. Trichinellosis surveillance–United States, 2008–2012. Morb Mortal Wkly Rep Surveill Summ. 2015;64(1):1–8. Wilson NO, Hall RL, Montgomery SP, Jones JL. Trichinellosis surveillance–United States, 2008–2012. Morb Mortal Wkly Rep Surveill Summ. 2015;64(1):1–8.
3.
go back to reference Taratuto AL, Venturiello SM. Trichinosis. Brain Pathol. 1997;7(1):663–72.CrossRef Taratuto AL, Venturiello SM. Trichinosis. Brain Pathol. 1997;7(1):663–72.CrossRef
4.
go back to reference Diaz JH, Warren RJ, Oster MJ. The disease ecology, epidemiology, clinical manifestations, and management of trichinellosis linked to consumption of wild animal meat. Wilderness Environ Med. 2020;31(2):235–44.CrossRef Diaz JH, Warren RJ, Oster MJ. The disease ecology, epidemiology, clinical manifestations, and management of trichinellosis linked to consumption of wild animal meat. Wilderness Environ Med. 2020;31(2):235–44.CrossRef
5.
go back to reference European Food Safety Authority and European Centre for Disease Prevention and Control (EFSA and ECDC. The European Union summary report on trends and sources of zoonoses, zoonotic agents and food-borne outbreaks in 2017. EFSA J Eur Food Saf Auth. 2018;16(12): e05500. European Food Safety Authority and European Centre for Disease Prevention and Control (EFSA and ECDC. The European Union summary report on trends and sources of zoonoses, zoonotic agents and food-borne outbreaks in 2017. EFSA J Eur Food Saf Auth. 2018;16(12): e05500.
6.
go back to reference Kahsay R, Gómez-Morales MA, Rivera HN, McAuliffe I, Pozio E, Handali S. A Bead-based assay for the detection of antibodies against Trichinella spp. infection in humans. Am J Trop Med Hyg. 2021;104(5):1858–62.CrossRef Kahsay R, Gómez-Morales MA, Rivera HN, McAuliffe I, Pozio E, Handali S. A Bead-based assay for the detection of antibodies against Trichinella spp. infection in humans. Am J Trop Med Hyg. 2021;104(5):1858–62.CrossRef
7.
go back to reference Wang ZQ, Fu GY, Jing FJ, Jin J, Ren HJ, Jiang P, Cui J. Detection of Trichinella spiralis circulating antigens in serum of experimentally infected mice by an IgY-mAb sandwich ELISA. Foodborne Pathog Dis. 2012;9(8):727–33.CrossRef Wang ZQ, Fu GY, Jing FJ, Jin J, Ren HJ, Jiang P, Cui J. Detection of Trichinella spiralis circulating antigens in serum of experimentally infected mice by an IgY-mAb sandwich ELISA. Foodborne Pathog Dis. 2012;9(8):727–33.CrossRef
8.
go back to reference Nishiyama T, Araki T, Mizuno N, Wada T, Ide T, Yamaguchi T. Detection of circulating antigens in human trichinellosis. Trans R Soc Trop Med Hyg. 1992;86(3):292–3.CrossRef Nishiyama T, Araki T, Mizuno N, Wada T, Ide T, Yamaguchi T. Detection of circulating antigens in human trichinellosis. Trans R Soc Trop Med Hyg. 1992;86(3):292–3.CrossRef
9.
go back to reference Thawornkuno C, Nogrado K, Adisakwattana P, Thiangtrongjit T, Reamtong O. Identification and profiling of Trichinella spiralis circulating antigens and proteins in sera of mice with trichinellosis. PLoS ONE. 2022;17(3): e0265013.CrossRef Thawornkuno C, Nogrado K, Adisakwattana P, Thiangtrongjit T, Reamtong O. Identification and profiling of Trichinella spiralis circulating antigens and proteins in sera of mice with trichinellosis. PLoS ONE. 2022;17(3): e0265013.CrossRef
10.
go back to reference Dupouy-Camet J, Kociecka W, Bruschi F, Bolas-Fernandez F, Pozio E. Opinion on the diagnosis and treatment of human trichinellosis. Expert Opin Pharmacother. 2002;3(8):1117–30.CrossRef Dupouy-Camet J, Kociecka W, Bruschi F, Bolas-Fernandez F, Pozio E. Opinion on the diagnosis and treatment of human trichinellosis. Expert Opin Pharmacother. 2002;3(8):1117–30.CrossRef
11.
go back to reference Soukup J, Cerny J, Cegan M, Kelbich P, Novotny T. Toxocariasis as a rare parasitic complication of a transthoracic spine surgery procedure. Medicina. 2021;57(12):1328.CrossRef Soukup J, Cerny J, Cegan M, Kelbich P, Novotny T. Toxocariasis as a rare parasitic complication of a transthoracic spine surgery procedure. Medicina. 2021;57(12):1328.CrossRef
12.
go back to reference Fan T, Zhang Y, Lv Y, Chang J, Bauer BA, Yang J, Wang CW. Cutaneous myiasis with eosinophilic pleural effusion: a case report. World J Clin Cases. 2021;9(18):4803–9.CrossRef Fan T, Zhang Y, Lv Y, Chang J, Bauer BA, Yang J, Wang CW. Cutaneous myiasis with eosinophilic pleural effusion: a case report. World J Clin Cases. 2021;9(18):4803–9.CrossRef
13.
go back to reference Park SJ, Jang CW, Kim YK, Seo YH, Kim KH, Kwon TG, Bae JH. Toxocariasis-associated acute perimyocarditis with cardiogenic shock: a case report. Am J Case Rep. 2021;22: e930573.CrossRef Park SJ, Jang CW, Kim YK, Seo YH, Kim KH, Kwon TG, Bae JH. Toxocariasis-associated acute perimyocarditis with cardiogenic shock: a case report. Am J Case Rep. 2021;22: e930573.CrossRef
14.
go back to reference Savu C, Melinte A, Grigorie V, Iliescu L, Diaconu C, Dimitriu M, Socea B, Stiru O, Varlas V, Savu C, et al. Primary pleural hydatidosis-a rare occurrence: a case report and literature review. Medicina. 2020;56(11):567.CrossRef Savu C, Melinte A, Grigorie V, Iliescu L, Diaconu C, Dimitriu M, Socea B, Stiru O, Varlas V, Savu C, et al. Primary pleural hydatidosis-a rare occurrence: a case report and literature review. Medicina. 2020;56(11):567.CrossRef
15.
go back to reference Aggarwal P, Subramanian S, Saini V, Aggarwal D. Filariasis presenting as isolated pleural effusion: a case report and mini review. Trop Doct. 2021;51(1):111–4.CrossRef Aggarwal P, Subramanian S, Saini V, Aggarwal D. Filariasis presenting as isolated pleural effusion: a case report and mini review. Trop Doct. 2021;51(1):111–4.CrossRef
16.
go back to reference Tourne M, Dupin C, Mordant P, Neuville M, Taillé C, Danel C. Autochthonous hydatid cyst of the lung. Ann Pathol. 2019;39(1):47–53.CrossRef Tourne M, Dupin C, Mordant P, Neuville M, Taillé C, Danel C. Autochthonous hydatid cyst of the lung. Ann Pathol. 2019;39(1):47–53.CrossRef
17.
go back to reference Hämäläinen S, Kantele A, Arvonen M, Hakala T, Karhukorpi J, Heikkinen J, Berg E, Vanamo K, Tyrväinen E, Heiskanen-Kosma T, et al. An autochthonous case of cystic echinococcosis in Finland, 2015. Eur Commun Dis Bull. 2015;20(42):30043. Hämäläinen S, Kantele A, Arvonen M, Hakala T, Karhukorpi J, Heikkinen J, Berg E, Vanamo K, Tyrväinen E, Heiskanen-Kosma T, et al. An autochthonous case of cystic echinococcosis in Finland, 2015. Eur Commun Dis Bull. 2015;20(42):30043.
18.
go back to reference Vallentin B, Carsin A, Dubus JC. Toxocariasis: an unusual cause of pleural effusion. Pediatr Pulmonol. 2015;50(10):E35-36.CrossRef Vallentin B, Carsin A, Dubus JC. Toxocariasis: an unusual cause of pleural effusion. Pediatr Pulmonol. 2015;50(10):E35-36.CrossRef
19.
go back to reference Oh Y, Kim JT, Kim MK, Chang YJ, Eom K, Park JG, Lee KM, Choe KH, An JY. Eosinophilic pleuritis due to sparganum: a case report. Korean J Parasitol. 2014;52(5):541–3.CrossRef Oh Y, Kim JT, Kim MK, Chang YJ, Eom K, Park JG, Lee KM, Choe KH, An JY. Eosinophilic pleuritis due to sparganum: a case report. Korean J Parasitol. 2014;52(5):541–3.CrossRef
20.
go back to reference Hernandez C, Cucunuba Z, Parra E, Toro G, Zambrano P, Ramírez JD. Chagas disease (Trypanosoma cruzi) and HIV co-infection in Colombia. Int J Infect Dis. 2014;26:146–8.CrossRef Hernandez C, Cucunuba Z, Parra E, Toro G, Zambrano P, Ramírez JD. Chagas disease (Trypanosoma cruzi) and HIV co-infection in Colombia. Int J Infect Dis. 2014;26:146–8.CrossRef
21.
go back to reference Wang J, Luo W, Shen P, He J, Zeng Y. Retrospective study of pleural parasitic infestations: a practical diagnostic approach. BMC Infect Dis. 2019;19(1):576.CrossRef Wang J, Luo W, Shen P, He J, Zeng Y. Retrospective study of pleural parasitic infestations: a practical diagnostic approach. BMC Infect Dis. 2019;19(1):576.CrossRef
22.
go back to reference Al-Tawfiq JA, Kim H, Memish ZA. Parasitic lung diseases. Eur Respir Rev. 2022;31(166):220093.CrossRef Al-Tawfiq JA, Kim H, Memish ZA. Parasitic lung diseases. Eur Respir Rev. 2022;31(166):220093.CrossRef
23.
go back to reference Ferreiro L, San José E, Valdés L. Tuberculous pleural effusion. Arch Bronconeumol. 2014;50(10):435–43.CrossRef Ferreiro L, San José E, Valdés L. Tuberculous pleural effusion. Arch Bronconeumol. 2014;50(10):435–43.CrossRef
24.
go back to reference Kociecka W. Trichinellosis: human disease, diagnosis and treatment. Vet Parasitol. 2000;93(3–4):365–83.CrossRef Kociecka W. Trichinellosis: human disease, diagnosis and treatment. Vet Parasitol. 2000;93(3–4):365–83.CrossRef
Metadata
Title
Pleural effusion caused by Trichinella spiralis infection: two case reports
Authors
Zhen-zhen Pan
Miao-juan Zhu
Yu-qiong Rong
Jiong Yang
Publication date
01-12-2023
Publisher
BioMed Central
Published in
BMC Infectious Diseases / Issue 1/2023
Electronic ISSN: 1471-2334
DOI
https://doi.org/10.1186/s12879-023-08047-9

Other articles of this Issue 1/2023

BMC Infectious Diseases 1/2023 Go to the issue
Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine