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BMC Cancer
Published in: BMC Cancer 1/2004

Open Access 01-12-2004 | Research article

Plasma prolactin in patients with colorectal cancer

Authors: Ahmad Reza Soroush, Hosein Mahmood zadeh, Mehrnush Moemeni, Behnam Shakiba, Sara Elmi

Published in: BMC Cancer | Issue 1/2004

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Abstract

Background

Colorectal cancer is a common malignancy of the gastrointestinal tract. It is the second cancer cause of death in females and third in males. Production of prolactin has been reported with several tumours. However, elevated prolactin plasma levels in colorectal cancer patients remained unclear.

Methods

In this cross sectional study serum prolactin and carcinoembryonic antigen (CEA) concentrations were assayed using immunoradiometric assay kits, preoperatively in 47 patients, and the results were compared with 51 age and sex matched controls.

Results

Prolactin and CEA concentration in patients were significantly more as compared with controls. Hyperprolactinemia was found in 36 (76.6%) patients, while 28 (59.6%) had high level of CEA.

Conclusions

Prolactin may be a better tumour marker than CEA in patients with colorectal malignancy.
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Metadata
Title
Plasma prolactin in patients with colorectal cancer
Authors
Ahmad Reza Soroush
Hosein Mahmood zadeh
Mehrnush Moemeni
Behnam Shakiba
Sara Elmi
Publication date
01-12-2004
Publisher
BioMed Central
Published in
BMC Cancer / Issue 1/2004
Electronic ISSN: 1471-2407
DOI
https://doi.org/10.1186/1471-2407-4-97

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