Top

Published in:

01-01-2016 | Topic Review

Pituitary metastasis: is there still a place for neurosurgical treatment?

Authors: V. Gilard, C. Alexandru, F. Proust, S. Derrey, P. Hannequin, O. Langlois

Published in: Journal of Neuro-Oncology | Issue 2/2016

Abstract

Pituitary metastases are uncommon, ranging from 1 to 5 % of all metastases. Between 10 and 30 % of pituitary lesions are symptomatic responsible for diabetes insipidus, visual field defect or cranial nerve palsy. Primary sites are lung or breast in two-thirds of cases. There is no current reference concerning treatment of such lesions. Overall survival is poor and depends on primary site. Although the role of surgery is currently limited, discussion is warranted in several indications for diagnostic or symptomatic purposes. We report two cases of symptomatic pituitary metastases in a context of breast cancer and review the litterature concerning the role of surgery and other treatment modalities.

Tomita H, Urui S, Kokunai T, Tamaki N (2000) A case of metastatic tumor of the pituitary gland presenting as a subarachnoid hemorrhage. No Shinkei Geka 28:1117–1120PubMed

Kim YH, Lee B, Lee KJ, Cho JH (2012) A case of pituitary metastasis from breast cancer that presented as left visual disturbance. J Korean Neurosurg Soc 51:94–97PubMedPubMedCentralCrossRef

Fassett DR, Couldwell WT (2004) Metastases to the pituitary gland. Neurosurg Focus 16:1–4

Morita A, Meyer FB, Laws ERJ (1998) Symptomatic pituitary metastases. J Neurosurg 89:69–73PubMedCrossRef

Zoli M, Mazzatenta D, Faustini-Fustini M, Pasquini E, Frank G (2013) Pituitary metastases: role of surgery. World Neurosurg 79:327–330PubMedCrossRef

He W, Chen F, Dalm B, Kirby PA, Greenlee JDW (2015) Metastatic involvement of the pituitary gland: a systematic review with pooled individual patient data analysis. Pituitary 18:159–168PubMedCrossRef

Teears RJ, Silverman EM (1975) Clinicopathologic review of 88 cases of carcinoma metastatic to the putuitary gland. Cancer 36:216–220PubMedCrossRef

Kam J, Kam J, Mann GB, Phillips C, Wentworth JM, King J, Linderman GJ (2015) Solitary pituitary metastasis from HER2-positive breast cancer: Pituitary metastasis in HER2+ breast cancer. Asia Pac J Clin Oncol. doi:10.1111/ajco.12353 PubMed

Fortunati N, Felicetti F, Donadio M, Grossi E, Michelon F, Ritorto G, Arvat E, Brignardello E (2015) Pituitary lesions in breast cancer patients: a report of three cases. Oncol Lett 9:2762–2766PubMedPubMedCentral

10.

Komninos J, Vlassopoulou V, Protopapa D, Korfias S, Kontogeorgos G, Sakas DE et al (2004) Tumors metastatic to the pituitary gland: case report and literature review. J Clin Endocrinol Metab 89:574–580PubMedCrossRef

11.

Feiz-Erfan I, Rao G, White W, McCutcheon I (2008) Efficacy of trans-septal trans-sphenoidal surgery in correcting visual symptoms caused by hematogenous metastases to the sella and pituitary gland. Skull Base 18:77–84PubMedPubMedCentralCrossRef

12.

Spinelli GP, Russo GL, Miele E, Prinzi N, Tomao F, Antonelli M, Giangaspero F, Stati V, Strudel M, Tomao S (2012) Breast cancer metastatic to the pituitary gland: a case report. World J Surg Oncol. doi:10.1186/1477-7819-10-137

13.

Eksi MS, Hasanov T, Yilmaz B, Akakin A, Bayri Y, Bozkurt SU et al (2014) Isolated metastasis of breast cancer to the pituitary gland. Neurol India 62:70–71PubMedCrossRef

14.

Marin F, Kovacs KT, Scheithauer BW, Young WFJ (1992) The pituitary gland in patients with breast carcinoma: a histologic and immunocytochemical study of 125 cases. Mayo Clin Proc 67:949–956PubMedCrossRef

15.

Gurling KJ, Scott GBD, Baron DN (1957) Metastases in pituitary tissue removed at hypophysectomy in women with mammary carcinoma. Br J Cancer 11:519PubMedPubMedCentralCrossRef

16.

Burkhardt T, Henze M, Kluth LA, Westphal M, Schmidt NO, Flitsch J (2015) Surgical management of pituitary metastases. Pituitary. doi:10.1007/s11102-015-0676-z

17.

Max MB, Deck MD, Rottenberg DA (1981) Pituitary metastasis: incidence in cancer patients and clinical differentiation from pituitary adenoma. Neurology 31:998PubMedCrossRef

18.

Kano H, Niranjan A, Kondziolka D, Flickinger JC, Lunsford LD (2009) Stereotactic radiosurgery for pituitary metastases. Surg Neurol 72:248–255PubMedCrossRef

19.

Hagerstrand I, Schonebeck J (1969) Metastases to the pituitary gland. Acta Pathol Microbiol Scand 75:1–4

20.

Mori Y, Kobayashi T, Shibamoto Y (2006) Stereotactic radiosurgery for metastatic tumors in the pituitary gland and the cavernous sinus. J Neurosurg 105:37–42PubMed

21.

Roessmann U, Kaufman B, Friede RL (1970) Metastatic lesions in the sella turcica and pituitary gland. Cancer 25:478–480PubMedCrossRef

22.

Ratti M, Passalacqua R, Poli R, Betri E, Crispino M, Poli R et al (2013) Pituitary gland metastasis from rectal cancer: report of a case and literature review. SpringerPlus 2:467PubMedPubMedCentralCrossRef

23.

Abrams HL, Spiro R, Goldstein N (1950) Metastases in carcinoma. Analysis of 1000 autopsied cases. Cancer 3:74–85PubMedCrossRef

24.

Houck WA, Olson KB, Horton J (1970) Clinical features of tumor metastasis to the pituitary. Cancer 26:656–659PubMedCrossRef

25.

Grisoli F, Leclercq TA, Robert F, Hardy J (1974) Pituitary metastases of breast cancer. Neurochirurgie 20:583–592PubMed

26.

Turaka A, Parsons RB, Buyyounouski MK (2012) Radiation therapy for pituitary metastasis: report of four cases. Tumori 98:e1–e6PubMed

27.

Hermet M, Delévaux I, Trouillier S, André M, Chazal J, Aumaître O (2009) Diabète insipide révélateur de métastases hypophysaires: quatre observations et revue de la littérature. Rev Médecine Interne 30:425–429CrossRef

28.

Lau G, Tan SY, Chiang G, Poh WT (1998) Bronchioloalveolar carcinoma with metastasis to the pituitary gland: a case report. J Clin Pathol 51:931–934PubMedPubMedCentralCrossRef

29.

Aaberg TMJ, Kay M, Sternau L (1995) Metastatic tumors to the pituitary. Am J Ophthalmol 119:779–785PubMedCrossRef

30.

Couldwell WT, Chandrasoma PT, Weiss MH (1989) Pituitary gland metastasis from adenocarcinoma of the prostate. Case report. J Neurosurg 71:138–140PubMedCrossRef

31.

Johnston PC, Black NR, McIlroy J, Sharkey R, Garvey A, Lindsay JR (2013) Hypopituitarism as the presenting feature of bronchogenic carcinoma with metastases to the pituitary gland. Indian J Endocrinol Metab 17:167–169PubMedPubMedCentral

32.

Altay T, Krisht KM, Couldwell WT (2012) Sellar and parasellar metastatic tumors. Int J Surg Oncol 2012:1–9CrossRef

33.

Sagoh M, Kodaki K, Ichikizaki K, Murakami K, Oizumi T, Kawase T et al (1996) Skull base metastasis from renal cell carcinoma presenting as abducens nerve paresis: report of two cases. No Shinkei Geka 24:829–833PubMed

34.

Shrieve DC, Hazard L, Boucher K, Jensen RL (2004) Dose fractionation in stereotactic radiotherapy for parasellar meningiomas: radiobiological considerations of efficacy and optic nerve tolerance. J Neurosurg 101(Suppl 3):390–395PubMed

Title: Pituitary metastasis: is there still a place for neurosurgical treatment?
Authors: V. Gilard
C. Alexandru
F. Proust
S. Derrey
P. Hannequin
O. Langlois
Publication date: 01-01-2016
Publisher: Springer US
Published in: Journal of Neuro-Oncology / Issue 2/2016
Print ISSN: 0167-594X
Electronic ISSN: 1573-7373
DOI: https://doi.org/10.1007/s11060-015-1967-y

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Pituitary metastasis: is there still a place for neurosurgical treatment?

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Please log in to get access to this content

Other articles of this Issue 2/2016

Pediatric brain tumors in a low/middle income country: does it differ from that in developed world?

A randomized phase I/II study of ABT-888 in combination with temozolomide in recurrent temozolomide resistant glioblastoma: an NRG oncology RTOG group study

Tryptophan PET predicts spatial and temporal patterns of post-treatment glioblastoma progression detected by contrast-enhanced MRI

Impact of provider level, training and gender on the utilization of palliative care and hospice in neuro-oncology: a North-American survey

Association between RAD 51 rs1801320 and susceptibility to glioblastoma

Preclinical studies of 5-fluoro-2′-deoxycytidine and tetrahydrouridine in pediatric brain tumors