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Acta Neurochirurgica
Published in: Acta Neurochirurgica 11/2008

01-11-2008 | Case Report

Pilomyxoid astrocytoma of the fourth ventricle in an adult

Authors: Tomoko Omura, Hiroshi Nawashiro, Hideo Osada, Katsuji Shima, Hitoshi Tsuda, Aida Shinsuke

Published in: Acta Neurochirurgica | Issue 11/2008

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Abstract

Pilomyxoid astrocytomas have been identified as a variant of pilocytic astrocytoma. They are listed as a novel clinico-pathological entity in the 2007 World Health Organisation (WHO) classification of tumours of the central nervous system. This tumour corresponds to a WHO grade II neoplasm whereas pilocytic astrocytoma corresponds to WHO grade I. We have encountered an infratentorial tumour with pilomyxoid features in an adult. A 25 year old man presented with tinnitus and hyperacusis. Brain MRI revealed a mass occupying the fourth ventricle. We performed partial resection, but no adjuvant therapy was given. The staining index for the anti-Ki-67 monoclonal antibody MIB-1 was less than 1% in this patient. Pilomyxoid astrocytomas are not limited to the hypothalamic/chiasmatic region in children. Additional knowledge and recognition of this entity is necessary to improve treatment of pilomyxoid astrocytoma.
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Metadata
Title
Pilomyxoid astrocytoma of the fourth ventricle in an adult
Authors
Tomoko Omura
Hiroshi Nawashiro
Hideo Osada
Katsuji Shima
Hitoshi Tsuda
Aida Shinsuke
Publication date
01-11-2008
Publisher
Springer Vienna
Published in
Acta Neurochirurgica / Issue 11/2008
Print ISSN: 0001-6268
Electronic ISSN: 0942-0940
DOI
https://doi.org/10.1007/s00701-008-0032-4

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