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01-01-2016 | Original Paper

Phytochemical analysis and effects of Pteris vittata extract on visual processes

Authors: Fazli Wahid, Taous Khan, Omer Shehzad, Adeeb Shehzad, You Young Kim

Published in: Journal of Natural Medicines | Issue 1/2016

Abstract

The present study was designed to explore the possible effects of Pteris vittata on visual sensitivity, ERG waves, and other components of the visual system. Electrophysiological techniques including electroretinography (ERG) were used in the present study. The phytochemical composition of the extract was investigated using liquid chromatography–mass spectrometry (LC–MS) techniques. The results indicated that the extract significantly augmented dark- and light-adapted ERG b-wave amplitude. Furthermore, these findings showed that P. vittata extract does not have Gamma-aminobutyric acid receptor antagonistic activity but may function as a retinal neural antagonist in bullfrog retina. P. vittata extract improved the visual sensitivity by 0.8 log unit of light intensity, and reduced the regeneration time for rhodopsin. The six main peaks obtained through LC–MS were identified as flavonoids. Based on these results, it was concluded that P. vittata extract or its constituents may be used to treat eye diseases.

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Title: Phytochemical analysis and effects of Pteris vittata extract on visual processes
Authors: Fazli Wahid
Taous Khan
Omer Shehzad
Adeeb Shehzad
You Young Kim
Publication date: 01-01-2016
Publisher: Springer Japan
Published in: Journal of Natural Medicines / Issue 1/2016
Print ISSN: 1340-3443
Electronic ISSN: 1861-0293
DOI: https://doi.org/10.1007/s11418-015-0930-8

At a glance: The STEP trials

Springer Medicine

Phytochemical analysis and effects of Pteris vittata extract on visual processes

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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