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Published in: BMC Pediatrics 1/2024

Open Access 01-12-2024 | Research

Physician’s conceptions of the decision-making process when managing febrile infants ≤ 60 days old: a phenomenographic qualitative study

Authors: Ioannis Orfanos, Rose-Marie Lindkvist, Erik G. A. Eklund, Kristina Elfving, Tobias Alfvén, Tom J. de Koning, Charlotte Castor

Published in: BMC Pediatrics | Issue 1/2024

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Abstract

Background

The management of febrile infants aged ≤ 60 days and adherence to guidelines vary greatly. Our objective was to describe the process of decision-making when managing febrile infants aged ≤ 60 days and to describe the factors that influenced this decision.

Methods

We conducted 6 focus group discussions with 19 clinically active physicians in the pediatric emergency departments of 2 university hospitals in Skåne region, Sweden. We followed an inductive qualitative design, using a phenomenological approach. A second-order perspective was used, focusing on how physicians perceived the phenomenon (managing fever in infants) rather than the phenomenon itself. The transcribed interviews were analyzed using a 7-step approach.

Results

Performing a lumbar puncture (LP) was conceived as a complex, emotionally and mentally laden procedure and dominated the group discussions. Three central categories emerged as factors that influenced the decision-making process on whether to perform an LP: 1) a possible focus of infection that could explain the origin of the fever, 2) questioning whether the temperature at home reported by the parents was a fever, especially if it was ≤ 38.2°C, and 3) the infant’s general condition and questioning the need for LP in case of well-appearing infants. Around these 3 central categories evolved 6 secondary categories that influenced the decision-making process of whether to perform an LP or not: 1) the physicians’ desire to be able to trust their judgement, 2) fearing the risk of failure, 3) avoiding burdensome work, 4) taking others into account, 5) balancing guidelines and resources, and 6) seeing a need to practice and learn to perform LP.

Conclusions

The difficulty and emotional load of performing an LP were important factors that influenced the decision-making process regarding whether to perform an LP. Physicians highlighted the importance of being able to rely on their clinical judgment and make independent decisions. Guidelines may consider allowing a degree of flexibility and independent thinking to take into account patients’ characteristics and needs.
Literature
1.
go back to reference Baker MD, Bell LM, Avner JR. Outpatient management without antibiotics of fever in selected infants. N Engl J Med. 1993;329(20):1437–41.CrossRefPubMed Baker MD, Bell LM, Avner JR. Outpatient management without antibiotics of fever in selected infants. N Engl J Med. 1993;329(20):1437–41.CrossRefPubMed
2.
go back to reference Baskin MN, O’Rourke EJ, Fleisher GR. Outpatient treatment of febrile infants 28 to 89 days of age with intramuscular administration of ceftriaxone. J Pediatr. 1992;120(1):22–7.CrossRefPubMed Baskin MN, O’Rourke EJ, Fleisher GR. Outpatient treatment of febrile infants 28 to 89 days of age with intramuscular administration of ceftriaxone. J Pediatr. 1992;120(1):22–7.CrossRefPubMed
3.
go back to reference Mintegi S, Bressan S, Gomez B, Da Dalt L, Blazquez D, Olaciregui I, et al. Accuracy of a sequential approach to identify young febrile infants at low risk for invasive bacterial infection. Emerg Med J. 2014;31(e1):e19-24.CrossRefPubMed Mintegi S, Bressan S, Gomez B, Da Dalt L, Blazquez D, Olaciregui I, et al. Accuracy of a sequential approach to identify young febrile infants at low risk for invasive bacterial infection. Emerg Med J. 2014;31(e1):e19-24.CrossRefPubMed
4.
go back to reference Pantell RH, Roberts KB, Adams WG, Dreyer BP, Kuppermann N, O’Leary ST, et al. Evaluation and management of well-appearing febrile infants 8 to 60 days old. Pediatrics. 2021;148(2). Pantell RH, Roberts KB, Adams WG, Dreyer BP, Kuppermann N, O’Leary ST, et al. Evaluation and management of well-appearing febrile infants 8 to 60 days old. Pediatrics. 2021;148(2).
5.
go back to reference Kuppermann N, Dayan PS, Levine DA, Vitale M, Tzimenatos L, Tunik MG, et al. A clinical prediction rule to identify febrile infants 60 days and younger at low risk for serious bacterial infections. JAMA Pediatr. 2019;173(4):342–51.CrossRefPubMedPubMedCentral Kuppermann N, Dayan PS, Levine DA, Vitale M, Tzimenatos L, Tunik MG, et al. A clinical prediction rule to identify febrile infants 60 days and younger at low risk for serious bacterial infections. JAMA Pediatr. 2019;173(4):342–51.CrossRefPubMedPubMedCentral
6.
go back to reference Biondi EA, McCulloh R, Staggs VS, Garber M, Hall M, Arana J, et al. Reducing Variability in the Infant Sepsis Evaluation (REVISE): a national quality initiative. Pediatrics. 2019;144(3). Biondi EA, McCulloh R, Staggs VS, Garber M, Hall M, Arana J, et al. Reducing Variability in the Infant Sepsis Evaluation (REVISE): a national quality initiative. Pediatrics. 2019;144(3).
7.
go back to reference Foster LZ, Beiner J, Duh-Leong C, Mascho K, Giordani V, Rinke ML, et al. Implementation of febrile infant management guidelines reduces hospitalization. Pediatr Qual Saf. 2020;5(1):e252.CrossRefPubMedPubMedCentral Foster LZ, Beiner J, Duh-Leong C, Mascho K, Giordani V, Rinke ML, et al. Implementation of febrile infant management guidelines reduces hospitalization. Pediatr Qual Saf. 2020;5(1):e252.CrossRefPubMedPubMedCentral
8.
go back to reference Byington CL, Reynolds CC, Korgenski K, Sheng X, Valentine KJ, Nelson RE, et al. Costs and infant outcomes after implementation of a care process model for febrile infants. Pediatrics. 2012;130(1):e16-24.CrossRefPubMedPubMedCentral Byington CL, Reynolds CC, Korgenski K, Sheng X, Valentine KJ, Nelson RE, et al. Costs and infant outcomes after implementation of a care process model for febrile infants. Pediatrics. 2012;130(1):e16-24.CrossRefPubMedPubMedCentral
9.
go back to reference Murray AL, Alpern E, Lavelle J, Mollen C. Clinical pathway effectiveness: febrile young infant clinical pathway in a pediatric emergency department. Pediatr Emerg Care. 2017;33(9):e33–7.CrossRefPubMed Murray AL, Alpern E, Lavelle J, Mollen C. Clinical pathway effectiveness: febrile young infant clinical pathway in a pediatric emergency department. Pediatr Emerg Care. 2017;33(9):e33–7.CrossRefPubMed
10.
go back to reference Gomez B, Fernandez-Uria A, Benito J, Lejarzegi A, Mintegi S. Impact of the step-by-step on febrile infants. Arch Dis Child. 2021;106(11):1047–9.CrossRefPubMed Gomez B, Fernandez-Uria A, Benito J, Lejarzegi A, Mintegi S. Impact of the step-by-step on febrile infants. Arch Dis Child. 2021;106(11):1047–9.CrossRefPubMed
11.
go back to reference Grol R. Successes and failures in the implementation of evidence-based guidelines for clinical practice. Med Care. 2001;39(8 Suppl 2):li46-54. Grol R. Successes and failures in the implementation of evidence-based guidelines for clinical practice. Med Care. 2001;39(8 Suppl 2):li46-54.
12.
go back to reference Sheldon TA, Cullum N, Dawson D, Lankshear A, Lowson K, Watt I, et al. What’s the evidence that NICE guidance has been implemented? results from a national evaluation using time series analysis, audit of patients’ notes, and interviews. BMJ. 2004;329(7473):999.CrossRefPubMedPubMedCentral Sheldon TA, Cullum N, Dawson D, Lankshear A, Lowson K, Watt I, et al. What’s the evidence that NICE guidance has been implemented? results from a national evaluation using time series analysis, audit of patients’ notes, and interviews. BMJ. 2004;329(7473):999.CrossRefPubMedPubMedCentral
13.
go back to reference Cabana MD, Rand CS, Powe NR, Wu AW, Wilson MH, Abboud PA, et al. Why don’t physicians follow clinical practice guidelines? A framework for improvement. Jama. 1999;282(15):1458–65.CrossRefPubMed Cabana MD, Rand CS, Powe NR, Wu AW, Wilson MH, Abboud PA, et al. Why don’t physicians follow clinical practice guidelines? A framework for improvement. Jama. 1999;282(15):1458–65.CrossRefPubMed
14.
go back to reference Fischer F, Lange K, Klose K, Greiner W, Kraemer A. Barriers and strategies in guideline implementation-a scoping review. Healthcare (Basel). 2016;4(3). Fischer F, Lange K, Klose K, Greiner W, Kraemer A. Barriers and strategies in guideline implementation-a scoping review. Healthcare (Basel). 2016;4(3).
15.
go back to reference Aronson PL, Thurm C, Alpern ER, Alessandrini EA, Williams DJ, Shah SS, et al. Variation in care of the febrile young infant <90 days in US pediatric emergency departments. Pediatrics. 2014;134(4):667–77.CrossRefPubMed Aronson PL, Thurm C, Alpern ER, Alessandrini EA, Williams DJ, Shah SS, et al. Variation in care of the febrile young infant <90 days in US pediatric emergency departments. Pediatrics. 2014;134(4):667–77.CrossRefPubMed
16.
go back to reference Pantell RH, Newman TB, Bernzweig J, Bergman DA, Takayama JI, Segal M, et al. Management and outcomes of care of fever in early infancy. JAMA. 2004;291(10):1203–12.CrossRefPubMed Pantell RH, Newman TB, Bernzweig J, Bergman DA, Takayama JI, Segal M, et al. Management and outcomes of care of fever in early infancy. JAMA. 2004;291(10):1203–12.CrossRefPubMed
17.
go back to reference Jain S, Cheng J, Alpern ER, Thurm C, Schroeder L, Black K, et al. Management of febrile neonates in US pediatric emergency departments. Pediatrics. 2014;133(2):187–95.CrossRefPubMed Jain S, Cheng J, Alpern ER, Thurm C, Schroeder L, Black K, et al. Management of febrile neonates in US pediatric emergency departments. Pediatrics. 2014;133(2):187–95.CrossRefPubMed
18.
go back to reference Klarenbeek NN, Keuning M, Hol J, Pajkrt D, Plötz FB. Fever without an apparent source in young infants: a multicenter retrospective evaluation of adherence to the dutch guidelines. Pediatr Infect Dis J. 2020;39(12):1075–80.CrossRefPubMed Klarenbeek NN, Keuning M, Hol J, Pajkrt D, Plötz FB. Fever without an apparent source in young infants: a multicenter retrospective evaluation of adherence to the dutch guidelines. Pediatr Infect Dis J. 2020;39(12):1075–80.CrossRefPubMed
19.
go back to reference Orfanos I, Elfving K, Sotoca Fernandez J, Wennlund L, Weiber S, Eklund EA, et al. Management and outcome of febrile infants </=60 days, with emphasis on infants </=21 days old, in Swedish pediatric emergency departments. Pediatr Infect Dis J. 2022;41(7):537–43.CrossRefPubMed Orfanos I, Elfving K, Sotoca Fernandez J, Wennlund L, Weiber S, Eklund EA, et al. Management and outcome of febrile infants </=60 days, with emphasis on infants </=21 days old, in Swedish pediatric emergency departments. Pediatr Infect Dis J. 2022;41(7):537–43.CrossRefPubMed
20.
go back to reference Ramgopal S, Walker LW, Tavarez MM, Nowalk AJ, Vitale MA. Serious bacterial infections in neonates presenting afebrile with history of fever. Pediatrics. 2019;144(2). Ramgopal S, Walker LW, Tavarez MM, Nowalk AJ, Vitale MA. Serious bacterial infections in neonates presenting afebrile with history of fever. Pediatrics. 2019;144(2).
21.
go back to reference Mintegi S, Gomez B, Carro A, Diaz H, Benito J. Invasive bacterial infections in young afebrile infants with a history of fever. Arch Dis Child. 2018;103(7):665–9.PubMed Mintegi S, Gomez B, Carro A, Diaz H, Benito J. Invasive bacterial infections in young afebrile infants with a history of fever. Arch Dis Child. 2018;103(7):665–9.PubMed
22.
go back to reference Orfanos I, Sotoca Fernandez J, Elfving K, Alfven T, Eklund EA. Paediatric emergency departments should manage young febrile and afebrile infants the same if they have a fever before presenting. Acta Paediatr. 2022;111(10):2004–9.CrossRefPubMedPubMedCentral Orfanos I, Sotoca Fernandez J, Elfving K, Alfven T, Eklund EA. Paediatric emergency departments should manage young febrile and afebrile infants the same if they have a fever before presenting. Acta Paediatr. 2022;111(10):2004–9.CrossRefPubMedPubMedCentral
23.
go back to reference Aronson PL, Schaeffer P, Niccolai LM, Shapiro ED, Fraenkel L. Parents’ perspectives on communication and shared decision making for febrile infants ≤60 days old. Pediatr Emerg Care. 2021;37(12):e1213-9. Aronson PL, Schaeffer P, Niccolai LM, Shapiro ED, Fraenkel L. Parents’ perspectives on communication and shared decision making for febrile infants ≤60 days old. Pediatr Emerg Care. 2021;37(12):e1213-9.
24.
go back to reference Sjöström B, Dahlgren LO. Applying phenomenography in nursing research. J Adv Nurs. 2002;40(3):339–45.CrossRefPubMed Sjöström B, Dahlgren LO. Applying phenomenography in nursing research. J Adv Nurs. 2002;40(3):339–45.CrossRefPubMed
27.
go back to reference O’Brien BC, Harris IB, Beckman TJ, Reed DA, Cook DA. Standards for reporting qualitative research: a synthesis of recommendations. Acad Med. 2014;89(9):1245–51.CrossRefPubMed O’Brien BC, Harris IB, Beckman TJ, Reed DA, Cook DA. Standards for reporting qualitative research: a synthesis of recommendations. Acad Med. 2014;89(9):1245–51.CrossRefPubMed
28.
go back to reference Creswell JW, Poth CN. Qualitative inquiry & research design: Choosing among five approaches. 4th ed: SAGE Publications; 2018. Creswell JW, Poth CN. Qualitative inquiry & research design: Choosing among five approaches. 4th ed: SAGE Publications; 2018.
29.
go back to reference Ryan RM, Deci EL. Intrinsic and extrinsic motivations: classic definitions and new directions. Contemp Educ Psychol. 2000;25(1):54–67.CrossRefPubMed Ryan RM, Deci EL. Intrinsic and extrinsic motivations: classic definitions and new directions. Contemp Educ Psychol. 2000;25(1):54–67.CrossRefPubMed
30.
go back to reference Aronson PL, Schaeffer P, Niccolai LM, Shapiro ED, Fraenkel L. Parents’ perspectives on communication and shared decision making for febrile infants ≤60 days old. Pediatr Emerg Care. 2021;37(12):e1213–9.CrossRefPubMedPubMedCentral Aronson PL, Schaeffer P, Niccolai LM, Shapiro ED, Fraenkel L. Parents’ perspectives on communication and shared decision making for febrile infants ≤60 days old. Pediatr Emerg Care. 2021;37(12):e1213–9.CrossRefPubMedPubMedCentral
31.
go back to reference De S, Tong A, Isaacs D, Craig JC. Parental perspectives on evaluation and management of fever in young infants: an interview study. Arch Dis Child. 2014;99(8):717–23.CrossRefPubMed De S, Tong A, Isaacs D, Craig JC. Parental perspectives on evaluation and management of fever in young infants: an interview study. Arch Dis Child. 2014;99(8):717–23.CrossRefPubMed
32.
go back to reference Aronson PL, Schaeffer P, Fraenkel L, Shapiro ED, Niccolai LM. Physicians’ and nurses’ perspectives on the decision to perform lumbar punctures on febrile infants ≤8 weeks old. Hosp Pediatr. 2019;9(6):405–14.CrossRefPubMedPubMedCentral Aronson PL, Schaeffer P, Fraenkel L, Shapiro ED, Niccolai LM. Physicians’ and nurses’ perspectives on the decision to perform lumbar punctures on febrile infants ≤8 weeks old. Hosp Pediatr. 2019;9(6):405–14.CrossRefPubMedPubMedCentral
33.
go back to reference Nigrovic LE, Kuppermann N, Neuman MI. Risk factors for traumatic or unsuccessful lumbar punctures in children. Ann Emerg Med. 2007;49(6):762–71.CrossRefPubMed Nigrovic LE, Kuppermann N, Neuman MI. Risk factors for traumatic or unsuccessful lumbar punctures in children. Ann Emerg Med. 2007;49(6):762–71.CrossRefPubMed
34.
go back to reference Nigrovic LE, McQueen AA, Neuman MI. Lumbar puncture success rate is not influenced by family-member presence. Pediatrics. 2007;120(4):e777-782.CrossRefPubMed Nigrovic LE, McQueen AA, Neuman MI. Lumbar puncture success rate is not influenced by family-member presence. Pediatrics. 2007;120(4):e777-782.CrossRefPubMed
35.
go back to reference Lugtenberg M, Zegers-van Schaick JM, Westert GP, Burgers JS. Why don’t physicians adhere to guideline recommendations in practice? an analysis of barriers among Dutch general practitioners. Implement Sci. 2009;4:54.CrossRefPubMedPubMedCentral Lugtenberg M, Zegers-van Schaick JM, Westert GP, Burgers JS. Why don’t physicians adhere to guideline recommendations in practice? an analysis of barriers among Dutch general practitioners. Implement Sci. 2009;4:54.CrossRefPubMedPubMedCentral
36.
go back to reference Greenhow TL, Hung YY, Pantell RH. Management and outcomes of previously healthy, full-term, febrile infants ages 7 to 90 days. Pediatrics. 2016;138(6). Greenhow TL, Hung YY, Pantell RH. Management and outcomes of previously healthy, full-term, febrile infants ages 7 to 90 days. Pediatrics. 2016;138(6).
37.
go back to reference Woolf SH, Grol R, Hutchinson A, Eccles M, Grimshaw J. Clinical guidelines: potential benefits, limitations, and harms of clinical guidelines. BMJ. 1999;318(7182):527–30.CrossRefPubMedPubMedCentral Woolf SH, Grol R, Hutchinson A, Eccles M, Grimshaw J. Clinical guidelines: potential benefits, limitations, and harms of clinical guidelines. BMJ. 1999;318(7182):527–30.CrossRefPubMedPubMedCentral
38.
go back to reference Brichko L, Mitra B, Cameron P. When guidelines guide us to harm. Emerg Med Australas. 2018;30(6):740–2.CrossRefPubMed Brichko L, Mitra B, Cameron P. When guidelines guide us to harm. Emerg Med Australas. 2018;30(6):740–2.CrossRefPubMed
39.
go back to reference Guerra-Farfan E, Garcia-Sanchez Y, Jornet-Gibert M, Nuñez JH, Balaguer-Castro M, Madden K. Clinical practice guidelines: The good, the bad, and the ugly. Injury. 2023;54 Suppl 3:S26-S29. Guerra-Farfan E, Garcia-Sanchez Y, Jornet-Gibert M, Nuñez JH, Balaguer-Castro M, Madden K. Clinical practice guidelines: The good, the bad, and the ugly. Injury. 2023;54 Suppl 3:S26-S29.
40.
go back to reference Mata DA, Ramos MA, Bansal N, Khan R, Guille C, Di Angelantonio E, et al. Prevalence of depression and depressive symptoms among resident physicians: a systematic review and meta-analysis. JAMA. 2015;314(22):2373–83.CrossRefPubMedPubMedCentral Mata DA, Ramos MA, Bansal N, Khan R, Guille C, Di Angelantonio E, et al. Prevalence of depression and depressive symptoms among resident physicians: a systematic review and meta-analysis. JAMA. 2015;314(22):2373–83.CrossRefPubMedPubMedCentral
41.
go back to reference Liao L. The physician as person framework: how human nature impacts empathy, depression, burnout, and the practice of medicine. Can Med Educ J. 2017;8(4):e92–6.CrossRefPubMedPubMedCentral Liao L. The physician as person framework: how human nature impacts empathy, depression, burnout, and the practice of medicine. Can Med Educ J. 2017;8(4):e92–6.CrossRefPubMedPubMedCentral
42.
go back to reference Ryan RM, Deci EL. Self-determination theory and the facilitation of intrinsic motivation, social development, and well-being. Am Psychol. 2000;55(1):68–78.CrossRefPubMed Ryan RM, Deci EL. Self-determination theory and the facilitation of intrinsic motivation, social development, and well-being. Am Psychol. 2000;55(1):68–78.CrossRefPubMed
43.
go back to reference Babenko O. Professional well-being of practicing physicians: the roles of autonomy, competence, and relatedness. Healthcare (Basel). 2018;6(1). Babenko O. Professional well-being of practicing physicians: the roles of autonomy, competence, and relatedness. Healthcare (Basel). 2018;6(1).
44.
go back to reference Aronson PL, Politi MC, Schaeffer P, Fleischer E, Shapiro ED, Niccolai LM, et al. Development of an app to facilitate communication and shared decision-making with parents of febrile infants ≤ 60 days old. Acad Emerg Med. 2021;28(1):46–59.CrossRefPubMed Aronson PL, Politi MC, Schaeffer P, Fleischer E, Shapiro ED, Niccolai LM, et al. Development of an app to facilitate communication and shared decision-making with parents of febrile infants ≤ 60 days old. Acad Emerg Med. 2021;28(1):46–59.CrossRefPubMed
Metadata
Title
Physician’s conceptions of the decision-making process when managing febrile infants ≤ 60 days old: a phenomenographic qualitative study
Authors
Ioannis Orfanos
Rose-Marie Lindkvist
Erik G. A. Eklund
Kristina Elfving
Tobias Alfvén
Tom J. de Koning
Charlotte Castor
Publication date
01-12-2024
Publisher
BioMed Central
Published in
BMC Pediatrics / Issue 1/2024
Electronic ISSN: 1471-2431
DOI
https://doi.org/10.1186/s12887-024-04548-x

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