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Published in: Supportive Care in Cancer 12/2021

01-12-2021 | Physical Therapy | Original Article

Fatigue and functional outcomes in cancer rehabilitation

Authors: Amanda Mack, Monica Arrigo, Twyla Fink, Karla Garrity, David Cox, Lauren Kwasnowski, John Wong

Published in: Supportive Care in Cancer | Issue 12/2021

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Abstract

Purpose

Cancer-related fatigue (CRF) is one of the most common symptoms experienced by oncology patients, though its impact on functional outcomes during inpatient rehabilitation is relatively unknown. The purpose of this study is to determine whether CRF severity on admission is related to functional gains following standard rehabilitation care in an inpatient oncology rehabilitation population.

Methods

A retrospective cohort study was conducted within an inpatient oncology unit at a long-term acute care hospital. Seventy-six patients admitted to the hospital between April and December 2015 with an oncology diagnosis, planned discharge, and completed standardized assessments of CRF and functional ability were included in this study. Patients received standard interdisciplinary rehabilitation services including physical and occupational therapy. CRF was assessed on admission using the Brief Fatigue Inventory, and functional abilities were assessed on admission and discharge using the basic mobility and daily activity domains of the Activity Measure for Post-Acute Care inpatient short forms (AM-PAC).

Results

Ninety-seven percent of patients reported CRF, and 57% reported severe CRF upon admission. Patients demonstrated on average a 30% and 14% reduction in functional impairment in basic mobility and daily activity respectively during their admission. There was no significant correlation found between CRF on admission and change in functional impairment.

Conclusion

This study contributes to existing literature in that it found patients who received inpatient rehabilitation services demonstrate significant improvement in their functional status despite reporting CRF upon admission to a long-term acute care hospital oncology unit.
Literature
3.
go back to reference Berger AM, Mooney K, Alvarez-Perez A, Breitbart WS, Carpenter KM, Cella D, Cleeland C, Dotan E, Eisenberger MA, Escalante CP, Jacobsen PB, Jankowski C, LeBlanc T, Ligibel JA, Loggers ET, Mandrell B, Murphy BA, Palesh O, Pirl WF, Plaxe SC, Riba MB, Rugo HS, Salvador C, Wagner L, Wagner-Johnston ND, Zachariah FJ, Bergman MA, Smith C (2015) Cancer-related fatigue, Version 2.2015. J of the National Compr Cancer Netw 13:1012–1039. https://doi.org/10.6004/jnccn.2015.0122CrossRef Berger AM, Mooney K, Alvarez-Perez A, Breitbart WS, Carpenter KM, Cella D, Cleeland C, Dotan E, Eisenberger MA, Escalante CP, Jacobsen PB, Jankowski C, LeBlanc T, Ligibel JA, Loggers ET, Mandrell B, Murphy BA, Palesh O, Pirl WF, Plaxe SC, Riba MB, Rugo HS, Salvador C, Wagner L, Wagner-Johnston ND, Zachariah FJ, Bergman MA, Smith C (2015) Cancer-related fatigue, Version 2.2015. J of the National Compr Cancer Netw 13:1012–1039. https://​doi.​org/​10.​6004/​jnccn.​2015.​0122CrossRef
16.
go back to reference Campbell KL, Winters-stone KM, Wiskemann J, May AM, Schwartz AL, Courneya KS, Zucker DS, Matthews CE, Ligibel JA, Gerber LH, Morris GS, Patel AV, Hue TF, Perna FM, Schmitz KH (2019) Exercise guidelines for cancer survivors: consensus statement form international multidisciplinary roundtable. Med Sci Sports Exerc 51(11):2375–2390. https://doi.org/10.1249/MSS.0000000000002116CrossRef Campbell KL, Winters-stone KM, Wiskemann J, May AM, Schwartz AL, Courneya KS, Zucker DS, Matthews CE, Ligibel JA, Gerber LH, Morris GS, Patel AV, Hue TF, Perna FM, Schmitz KH (2019) Exercise guidelines for cancer survivors: consensus statement form international multidisciplinary roundtable. Med Sci Sports Exerc 51(11):2375–2390. https://​doi.​org/​10.​1249/​MSS.​0000000000002116​CrossRef
22.
go back to reference Jette AM, Haley SM, Coster W, Ni P (2015) Boston University Activity Measure for Post-Acute Care: AM-PAC short forms for inpatient and outpatient settings instruction manual (v. 9). Trustees of Boston University under license to CREcare, LLC Jette AM, Haley SM, Coster W, Ni P (2015) Boston University Activity Measure for Post-Acute Care: AM-PAC short forms for inpatient and outpatient settings instruction manual (v. 9). Trustees of Boston University under license to CREcare, LLC
Metadata
Title
Fatigue and functional outcomes in cancer rehabilitation
Authors
Amanda Mack
Monica Arrigo
Twyla Fink
Karla Garrity
David Cox
Lauren Kwasnowski
John Wong
Publication date
01-12-2021
Publisher
Springer Berlin Heidelberg
Published in
Supportive Care in Cancer / Issue 12/2021
Print ISSN: 0941-4355
Electronic ISSN: 1433-7339
DOI
https://doi.org/10.1007/s00520-021-06405-4

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