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Published in:

01-11-2009 | Review Article

Photodynamic therapy in dermatology: a review

Authors: Sonal Choudhary, Keyvan Nouri, Mohamed L. Elsaie

Published in: Lasers in Medical Science | Issue 6/2009

Abstract

Photodynamic therapy (PDT) is used for the prevention and treatment of non-melanoma skin cancer. Until recently, clinically approved indications have been restricted to actinic keratoses, nodular and superficial basal cell carcinoma, and, since 2006, Bowen disease. However, the range of indications has been expanding continuously. PDT is also used for the treatment of non-malignant conditions such as acne vulgaris and leishmaniasis, as well as for treating premature skin aging due to sun exposure. The production of reactive oxygen intermediates like singlet oxygen depends on the light dose applied as well as the concentration and localization of the photosensitizer in the diseased tissue. Either cytotoxic effects resulting in tumor destruction or immunomodulatory effects improving inflammatory skin conditions are induced. Treating superficial non-melanoma skin cancer, PDT has been shown to be highly efficient, despite the low level of invasiveness. The excellent cosmetic results after treatment are beneficial, too.

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Title: Photodynamic therapy in dermatology: a review
Authors: Sonal Choudhary
Keyvan Nouri
Mohamed L. Elsaie
Publication date: 01-11-2009
Publisher: Springer-Verlag
Published in: Lasers in Medical Science / Issue 6/2009
Print ISSN: 0268-8921
Electronic ISSN: 1435-604X
DOI: https://doi.org/10.1007/s10103-009-0716-x

At a glance: The STEP trials

Springer Medicine

Photodynamic therapy in dermatology: a review

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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