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01-08-2015 | Case Report

Phosphaturic mesenchymal tumor of the tibia with oncogenic osteomalacia in a teenager

Authors: Shannon G. Farmakis, Marilyn J. Siegel

Published in: Pediatric Radiology | Issue 9/2015

Abstract

Phosphaturic mesenchymal tumor is an uncommon cause of a paraneoplastic syndrome that can be associated with osteogenic osteomalacia. This tumor most commonly occurs in middle-aged men and women. We report a rare case of a phosphaturic mesenchymal tumor in a 16-year-old girl with multiple fractures as a result of severe osteoporosis. CT and MRI showed a mass arising from the tibia.

DOTATATE is short for the compound title of gallium [Ga-68]-N-[(4,7,10-Tricarboxymethyl-1,4,7,10-tetraazacyclododec-1-yl)acetyl]-D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophanyl-L-lysyl-L-threoninyl-L-cysteinyl-L-threonine-cyclic(2–7)disulfide. DOTATATE is an investigational diagnostic somatostatin analogue peptide PET agent used to track down neuroendocrine tumors.

68Ga-DOTANOC is short for 68Ga-labelled [1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid]-1-Nal3-octreotide. It is also a PET radiopharmaceutical agent that binds to somatostatin receptors.

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Title: Phosphaturic mesenchymal tumor of the tibia with oncogenic osteomalacia in a teenager
Authors: Shannon G. Farmakis
Marilyn J. Siegel
Publication date: 01-08-2015
Publisher: Springer Berlin Heidelberg
Published in: Pediatric Radiology / Issue 9/2015
Print ISSN: 0301-0449
Electronic ISSN: 1432-1998
DOI: https://doi.org/10.1007/s00247-015-3301-4

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Phosphaturic mesenchymal tumor of the tibia with oncogenic osteomalacia in a teenager

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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