Skip to main content
Top
Published in: CNS Drugs 1/2007

01-01-2007 | Therapy in Practice

Pharmacological Management of Attention-Deficit Hyperactivity Disorder in Adolescents

Special Considerations

Author: Prof. Philip Hazell

Published in: CNS Drugs | Issue 1/2007

Login to get access

Abstract

Approximately one-half of children medicated for attention-deficit hyperactivity disorder (ADHD) will continue to experience sufficient impairment during adolescence to warrant the continuation of their treatment; a smaller number of people with ADHD may require treatment for the first time during adolescence.The academic and social demands of adolescence can exaggerate the impairment caused by attentional problems, as adolescents, more so than children, have activities in the afternoon and evening that will tax their attentional abilities.
Stimulant and nonstimulant medications are likely to be as effective for adolescent patients as they are for younger children, provided treatment adherence is satisfactory. Long-acting medications are preferred over immediate-release compounds as they provide better coverage of symptoms throughout the day. Patterns of comorbidity with ADHD change from childhood to adolescence and may require a shift in treatment strategy. The choice of time to discontinue treatment should be a decision shared by the clinician and the patient. A negotiated trial of time off treatment followed by a review of the patient’s symptoms can avert premature discontinuation of treatment.
Footnotes
1
The use of trade names is for product identification purposes only and does not imply endorsement.
 
Literature
1.
go back to reference Biederman J, Mick E, Faraone SV. Age-dependent decline of symptoms of attention deficit hyperactivity disorder: impact of remission definition and symptom type. Am J Psychiatry 2000; 157: 816–8PubMed Biederman J, Mick E, Faraone SV. Age-dependent decline of symptoms of attention deficit hyperactivity disorder: impact of remission definition and symptom type. Am J Psychiatry 2000; 157: 816–8PubMed
2.
go back to reference Cuffe SP, McKeown RE, Jackson KL, et al. Prevalence of attention-deficit/hyperactivity disorder in a community sample of older adolescents. J Am Acad Child Adolesc Psychiatry 2001; 40: 1037–44PubMed Cuffe SP, McKeown RE, Jackson KL, et al. Prevalence of attention-deficit/hyperactivity disorder in a community sample of older adolescents. J Am Acad Child Adolesc Psychiatry 2001; 40: 1037–44PubMed
3.
go back to reference Rucklidge JJ, Tannock R. Psychiatric, psychosocial, and cognitive functioning of female adolescents with ADHD. J Am Acad Child Adolesc Psychiatry 2001; 40: 530–40PubMed Rucklidge JJ, Tannock R. Psychiatric, psychosocial, and cognitive functioning of female adolescents with ADHD. J Am Acad Child Adolesc Psychiatry 2001; 40: 530–40PubMed
4.
go back to reference Collishaw S, Maughan B, Goodman R, et al. Time trends in adolescent mental health. J Child Psychol Psychiatry 2004; 45: 1350–62PubMed Collishaw S, Maughan B, Goodman R, et al. Time trends in adolescent mental health. J Child Psychol Psychiatry 2004; 45: 1350–62PubMed
5.
go back to reference Thomas CP, Conrad P, Casier R, et al. Trends in the use of psychotropic medications among adolescents, 1994 to 2001. Psychiatr Serv 2006; 57: 63–9PubMed Thomas CP, Conrad P, Casier R, et al. Trends in the use of psychotropic medications among adolescents, 1994 to 2001. Psychiatr Serv 2006; 57: 63–9PubMed
6.
go back to reference Wolraich ML, Wibbelsman CJ, Brown TE, et al. Attention-deficit/hyperactivity disorder among adolescents: a review of the diagnosis, treatment, and clinical implications. Pediatrics 2005; 115: 1734–46PubMed Wolraich ML, Wibbelsman CJ, Brown TE, et al. Attention-deficit/hyperactivity disorder among adolescents: a review of the diagnosis, treatment, and clinical implications. Pediatrics 2005; 115: 1734–46PubMed
7.
go back to reference Biederman J. Attention-deficity/hyperactivity disorder: a selective overview. Biol Psychiatry 2005; 57: 1215–20PubMed Biederman J. Attention-deficity/hyperactivity disorder: a selective overview. Biol Psychiatry 2005; 57: 1215–20PubMed
8.
go back to reference Wilens TE, Biederman J, Spencer TJ. Attention deficit/hyperactivity disorder across the lifespan. Ann Rev Med 2002; 53: 113–31PubMed Wilens TE, Biederman J, Spencer TJ. Attention deficit/hyperactivity disorder across the lifespan. Ann Rev Med 2002; 53: 113–31PubMed
9.
go back to reference Upadhyaya HP, Rose K, Wang W, et al. Attention-deficit/ hyperactivity disorder, medication treatment, and substance use patterns among adolescents and young adults. J Child Adolesc Psychopharmacol 2005; 15: 799–809PubMed Upadhyaya HP, Rose K, Wang W, et al. Attention-deficit/ hyperactivity disorder, medication treatment, and substance use patterns among adolescents and young adults. J Child Adolesc Psychopharmacol 2005; 15: 799–809PubMed
10.
go back to reference Potter AS, Newhouse PA. Effects of acute nicotine administration on behavioral inhibition in adolescents with attention-deficit/hyperactivity disorder. Psychopharmacol 2004; 176: 182–94 Potter AS, Newhouse PA. Effects of acute nicotine administration on behavioral inhibition in adolescents with attention-deficit/hyperactivity disorder. Psychopharmacol 2004; 176: 182–94
11.
go back to reference Abel EL. The relationship between cannabis and violence: a review. Psychol Bull 1977; 84: 193–211PubMed Abel EL. The relationship between cannabis and violence: a review. Psychol Bull 1977; 84: 193–211PubMed
12.
go back to reference Smith BH, Pelham Jr WE, Gnagy E, et al. The reliability, validity, and unique contributions of self-report by adolescents receiving treatment for attention-deficit/hyperactivity disorder. J Consult Clin Psychol 2000; 68: 489–99PubMed Smith BH, Pelham Jr WE, Gnagy E, et al. The reliability, validity, and unique contributions of self-report by adolescents receiving treatment for attention-deficit/hyperactivity disorder. J Consult Clin Psychol 2000; 68: 489–99PubMed
13.
go back to reference University Associates in Psychiatry. IBMPC enter and score programs: the cross informant program for the CBCL/4-18, YSR and TRF. Burlington (VT). University of Vermont, 1993 University Associates in Psychiatry. IBMPC enter and score programs: the cross informant program for the CBCL/4-18, YSR and TRF. Burlington (VT). University of Vermont, 1993
14.
go back to reference Smith BH, Waschbusch DA, Willoughby MT, et al. The efficacy, safety, and practicality of treatments for adolescents with attention-deficit/hyperactivity disorder (ADHD). Clin Child Family Psychol Rev 2000; 3: 243–67 Smith BH, Waschbusch DA, Willoughby MT, et al. The efficacy, safety, and practicality of treatments for adolescents with attention-deficit/hyperactivity disorder (ADHD). Clin Child Family Psychol Rev 2000; 3: 243–67
15.
go back to reference Schachter HM, Pham B, King J, et al. How efficacious and safe is short-acting methylphenidate for the treatment of attention-deficit disorder in children and adolescents: a meta-analysis. CMAJ 2001; 165: 1475–88PubMedPubMedCentral Schachter HM, Pham B, King J, et al. How efficacious and safe is short-acting methylphenidate for the treatment of attention-deficit disorder in children and adolescents: a meta-analysis. CMAJ 2001; 165: 1475–88PubMedPubMedCentral
16.
go back to reference Hazell PL, Lewin TJ, McDowell MJ, et al. Factors associated with medium-term response to psychostimulant medication. J Paediatr Child Health 1999; 35: 264–9PubMed Hazell PL, Lewin TJ, McDowell MJ, et al. Factors associated with medium-term response to psychostimulant medication. J Paediatr Child Health 1999; 35: 264–9PubMed
17.
go back to reference Spencer TJ, Wilens TE, Biederman J, et al. Efficacy and safety of mixed amphetamine salts extended release (Adderall XR) in the management of attention-deficit/hyperactivity disorder in adolescent patients: a 4-week, randomized, double-blind, placebo-controlled, parallel-group study. Clin Ther 2006; 28: 266–79PubMed Spencer TJ, Wilens TE, Biederman J, et al. Efficacy and safety of mixed amphetamine salts extended release (Adderall XR) in the management of attention-deficit/hyperactivity disorder in adolescent patients: a 4-week, randomized, double-blind, placebo-controlled, parallel-group study. Clin Ther 2006; 28: 266–79PubMed
18.
go back to reference Swanson J, Gupta S, Lam A, et al. Development of a new once-a-day formulation of methylphenidate for the treatment of attention-deficit/hyperactivity disorder: proof-of-concept and proof-of-product studies. Arch Gen Psychiatry 2003; 60: 204–11PubMed Swanson J, Gupta S, Lam A, et al. Development of a new once-a-day formulation of methylphenidate for the treatment of attention-deficit/hyperactivity disorder: proof-of-concept and proof-of-product studies. Arch Gen Psychiatry 2003; 60: 204–11PubMed
19.
go back to reference Wilens TE, McBurnett K, Bukstein O, et al. Multisite controlled study of OROS methylphenidate in the treatment of adolescents with attention-deficit/hyperactivity disorder. Arch Pediatr Adolesc Med 2006; 160: 82–90PubMed Wilens TE, McBurnett K, Bukstein O, et al. Multisite controlled study of OROS methylphenidate in the treatment of adolescents with attention-deficit/hyperactivity disorder. Arch Pediatr Adolesc Med 2006; 160: 82–90PubMed
20.
go back to reference Wolraich ML, Greenhill LL, Pelham W. Randomized, controlled trial of OROS methylphenidate once a day in children wtih attention-deficit disorder. Pediatrics 2001; 108: 883–92PubMed Wolraich ML, Greenhill LL, Pelham W. Randomized, controlled trial of OROS methylphenidate once a day in children wtih attention-deficit disorder. Pediatrics 2001; 108: 883–92PubMed
21.
go back to reference Cox DJ, Humphrey JW, Merkel RL, et al. Controlled-release methylphenidate improves attention during on-road driving by adolescents with attention-deficit/hyperactivity disorder. J Am Board Fam Pract 2004; 17: 235–9PubMed Cox DJ, Humphrey JW, Merkel RL, et al. Controlled-release methylphenidate improves attention during on-road driving by adolescents with attention-deficit/hyperactivity disorder. J Am Board Fam Pract 2004; 17: 235–9PubMed
22.
go back to reference Cox DJ, Merkel RL, Penberthy JK, et al. Impact of methylphenidate delivery profiles on driving performance of adolescents with attention-deficit/hyperactivity disorder: a pilot study. J Am Acad Child Adolesc Psychiatry 2004; 43: 269–75PubMed Cox DJ, Merkel RL, Penberthy JK, et al. Impact of methylphenidate delivery profiles on driving performance of adolescents with attention-deficit/hyperactivity disorder: a pilot study. J Am Acad Child Adolesc Psychiatry 2004; 43: 269–75PubMed
23.
go back to reference Greenhill LL, Findling RL, Swanson JM, et al. A double-blind, placebo-controlled study of modified-release methylphenidate in children with attention-deficit/hyperactivity disorder. Pediatrics 2002; 109: E39PubMed Greenhill LL, Findling RL, Swanson JM, et al. A double-blind, placebo-controlled study of modified-release methylphenidate in children with attention-deficit/hyperactivity disorder. Pediatrics 2002; 109: E39PubMed
24.
go back to reference Lyseng-Williamson KA, Keating GM. Extended-release methylphenidate (Ritalin LA). Drugs 2002; 62: 2251–9PubMed Lyseng-Williamson KA, Keating GM. Extended-release methylphenidate (Ritalin LA). Drugs 2002; 62: 2251–9PubMed
26.
go back to reference Arnold LE, Lindsay RL, Conners CK, et al. A double-blind, placebo-controlled withdrawal trial of dexmethylphenidate hydrochloride in children with attention deficit hyperactivity disorder. J Child Adolesc Psychopharmacol 2004; 14: 542–54PubMed Arnold LE, Lindsay RL, Conners CK, et al. A double-blind, placebo-controlled withdrawal trial of dexmethylphenidate hydrochloride in children with attention deficit hyperactivity disorder. J Child Adolesc Psychopharmacol 2004; 14: 542–54PubMed
28.
go back to reference Bostic JQ, Biederman J, Spencer TJ, et al. Pemoline treatment of adolescents with attention deficit hyperactivity disorder: a short-term controlled trial. J Child Adolesc Psychopharmacol 2000; 10: 205–16PubMed Bostic JQ, Biederman J, Spencer TJ, et al. Pemoline treatment of adolescents with attention deficit hyperactivity disorder: a short-term controlled trial. J Child Adolesc Psychopharmacol 2000; 10: 205–16PubMed
29.
go back to reference Wilens TE, Kratochvil C, Newcorn JH, et al. Do children and adolescents with ADHD respond differently to atomoxetine? J Am Acad Child Adolesc Psychiatry 2006; 45: 149–57PubMed Wilens TE, Kratochvil C, Newcorn JH, et al. Do children and adolescents with ADHD respond differently to atomoxetine? J Am Acad Child Adolesc Psychiatry 2006; 45: 149–57PubMed
30.
go back to reference Daviss WB, Bentivoglio P, Racusin R, et al. Bupropion sustained release in adolescents with comorbid attention-deficit/ hyperactivity disorder and depression. J Am Acad Child Adolesc Psychiatry 2001; 40: 307–14PubMed Daviss WB, Bentivoglio P, Racusin R, et al. Bupropion sustained release in adolescents with comorbid attention-deficit/ hyperactivity disorder and depression. J Am Acad Child Adolesc Psychiatry 2001; 40: 307–14PubMed
31.
go back to reference Riggs PD, Leon SL, Mikulich SK, et al. An open trial of bupropion for ADHD in adolescents with substance use disorders and conduct disorder. J Am Acad Child Adolesc Psychiatry 1998; 37: 1271–8PubMed Riggs PD, Leon SL, Mikulich SK, et al. An open trial of bupropion for ADHD in adolescents with substance use disorders and conduct disorder. J Am Acad Child Adolesc Psychiatry 1998; 37: 1271–8PubMed
32.
go back to reference Solhkhah R, Wilens TE, Daly J, et al. Bupropion SR for the treatment of substance-abusing outpatient adolescents with attention-deficit/hyperactivity disorder and mood disorders. J Child Adolesc Psychopharmacol 2005; 15: 777–86PubMed Solhkhah R, Wilens TE, Daly J, et al. Bupropion SR for the treatment of substance-abusing outpatient adolescents with attention-deficit/hyperactivity disorder and mood disorders. J Child Adolesc Psychopharmacol 2005; 15: 777–86PubMed
33.
go back to reference Barrickman LL, Perry PJ, Allen AJ, et al. Bupropion versus methylphenidate in the treatment of attention-deficit hyperactivity disorder. J Am Acad Child Adolesc Psychiatry 1995; 34: 649–57PubMed Barrickman LL, Perry PJ, Allen AJ, et al. Bupropion versus methylphenidate in the treatment of attention-deficit hyperactivity disorder. J Am Acad Child Adolesc Psychiatry 1995; 34: 649–57PubMed
34.
go back to reference Biederman J, Baldessarini RJ, Wright V, et al. A double-blind placebo controlled study of desipramine in the treatment of ADD: I. Efficacy. J Am Acad Child Adolesc Psychiatry 1989; 28: 777–84PubMed Biederman J, Baldessarini RJ, Wright V, et al. A double-blind placebo controlled study of desipramine in the treatment of ADD: I. Efficacy. J Am Acad Child Adolesc Psychiatry 1989; 28: 777–84PubMed
35.
go back to reference Spencer T, Biederman J, Coffey B, et al. A double-blind comparison of desipramine and placebo in children and adolescents with chronic tic disorder and comorbid attention-deficit/hyper-activity disorder. Arch Gen Psychiatry 2002; 59: 649–56PubMed Spencer T, Biederman J, Coffey B, et al. A double-blind comparison of desipramine and placebo in children and adolescents with chronic tic disorder and comorbid attention-deficit/hyper-activity disorder. Arch Gen Psychiatry 2002; 59: 649–56PubMed
36.
go back to reference Prince JB, Wilens TE, Biederman J, et al. A controlled study of nortriptyline in children and adolescents with attention deficit hyperactivity disorder. J Child Adolesc Psychopharmacol 2000; 10(3): 193–204PubMed Prince JB, Wilens TE, Biederman J, et al. A controlled study of nortriptyline in children and adolescents with attention deficit hyperactivity disorder. J Child Adolesc Psychopharmacol 2000; 10(3): 193–204PubMed
37.
go back to reference Werry JS, Biederman J, Thisted R, et al. Resolved: cardiac arrhythmias make desipramine an unacceptable choice in children. J Am Acad Child Adolesc Psychiatry 1995; 34: 1239–45PubMed Werry JS, Biederman J, Thisted R, et al. Resolved: cardiac arrhythmias make desipramine an unacceptable choice in children. J Am Acad Child Adolesc Psychiatry 1995; 34: 1239–45PubMed
38.
go back to reference Greenhill LL, Pliszka S, Dulcan MK, et al. Practice parameter for the use of stimulant medications in the treatment of children, adolescents, and adults. J Am Acad Child Adolesc Psychiatry 2002; 41(2 Suppl.): 26–49S Greenhill LL, Pliszka S, Dulcan MK, et al. Practice parameter for the use of stimulant medications in the treatment of children, adolescents, and adults. J Am Acad Child Adolesc Psychiatry 2002; 41(2 Suppl.): 26–49S
39.
go back to reference Taylor E, Dopfner M, Sergeant J, et al. European clinical guidelines for hyperkinetic disorder: first upgrade. Eur Child Adoles Psychiatry 2004; 13 Suppl. 1: 7–30 Taylor E, Dopfner M, Sergeant J, et al. European clinical guidelines for hyperkinetic disorder: first upgrade. Eur Child Adoles Psychiatry 2004; 13 Suppl. 1: 7–30
40.
go back to reference Charach A, Ickowicz A, Schachar R. Stimulant treatment over five years: adherence, effectiveness, and adverse effects. J Am Acad Child Adolesc Psychiatry 2004; 43: 559–67PubMed Charach A, Ickowicz A, Schachar R. Stimulant treatment over five years: adherence, effectiveness, and adverse effects. J Am Acad Child Adolesc Psychiatry 2004; 43: 559–67PubMed
41.
go back to reference Marcus SC, Wan GJ, Kemner JE, et al. Continuity of methylphenidate treatment for attention-deficit/hyperactivity disorder. Arch Pediatr Adolesc Med 2005; 159: 572–8PubMed Marcus SC, Wan GJ, Kemner JE, et al. Continuity of methylphenidate treatment for attention-deficit/hyperactivity disorder. Arch Pediatr Adolesc Med 2005; 159: 572–8PubMed
42.
go back to reference Findling RL, Short EJ, Manos MJ. Developmental aspects of psychostimulant treatment in children and adolescents with attention-deficit/hyperactivity disorder. J Am Acad Child Adolesc Psychiatry 2001; 40: 1441–7PubMed Findling RL, Short EJ, Manos MJ. Developmental aspects of psychostimulant treatment in children and adolescents with attention-deficit/hyperactivity disorder. J Am Acad Child Adolesc Psychiatry 2001; 40: 1441–7PubMed
43.
go back to reference Gordon SM, Tulak F, Troncale J. Prevalence and characteristics of adolescents patients with co-occurring ADHD and substance dependence. J Addict Dis 2004; 23: 31–40PubMed Gordon SM, Tulak F, Troncale J. Prevalence and characteristics of adolescents patients with co-occurring ADHD and substance dependence. J Addict Dis 2004; 23: 31–40PubMed
44.
go back to reference Wilson JJ, Levin FR. Attention-deficit/hyperactivity disorder and early-onset substance use disorders. J Child Adolesc Psychopharmacol 2005; 15: 751–63PubMed Wilson JJ, Levin FR. Attention-deficit/hyperactivity disorder and early-onset substance use disorders. J Child Adolesc Psychopharmacol 2005; 15: 751–63PubMed
45.
go back to reference Wilens TE, Monuteaux MC, Snyder LE, et al. The clinical dilemma of using medications in substance-abusing adolescents and adults with attention-deficit/hyperactivity disorder: what does the literature tell us? J Child Adolesc Psychopharmacol 2005; 15: 787–98PubMed Wilens TE, Monuteaux MC, Snyder LE, et al. The clinical dilemma of using medications in substance-abusing adolescents and adults with attention-deficit/hyperactivity disorder: what does the literature tell us? J Child Adolesc Psychopharmacol 2005; 15: 787–98PubMed
46.
go back to reference Levin FR, Evans SM, Brooks DJ, et al. Treatment of metha-done-maintained patients with adult ADHD: double-blind comparison of methylphenidate, bupropion and placebo. Drug Alcohol Depend 2006; 81: 137–48PubMed Levin FR, Evans SM, Brooks DJ, et al. Treatment of metha-done-maintained patients with adult ADHD: double-blind comparison of methylphenidate, bupropion and placebo. Drug Alcohol Depend 2006; 81: 137–48PubMed
47.
go back to reference Pliszka SR, Greenhill LL, Crismon ML, et al. The Texas Children’s Medication Algorithm Project: report of the Texas Consensus Conference Panel on medication treatment of childhood attention-deficit/hyperactivity disorder (Pt II). J Am Acad Child Adolesc Psychiatry 2000; 39: 920–7PubMed Pliszka SR, Greenhill LL, Crismon ML, et al. The Texas Children’s Medication Algorithm Project: report of the Texas Consensus Conference Panel on medication treatment of childhood attention-deficit/hyperactivity disorder (Pt II). J Am Acad Child Adolesc Psychiatry 2000; 39: 920–7PubMed
48.
go back to reference Faedda GL, Baldessarini RJ, Glovinsky IP, et al. Treatment-emergent mania in pediatric bipolar disorder: a retrospective case review. J Affect Disord 2004; 82: 149–58PubMed Faedda GL, Baldessarini RJ, Glovinsky IP, et al. Treatment-emergent mania in pediatric bipolar disorder: a retrospective case review. J Affect Disord 2004; 82: 149–58PubMed
49.
go back to reference Henderson TA. Mania induction associated with atomoxetine. J Clin Psychopharmacol 2004; 24: 567–8PubMed Henderson TA. Mania induction associated with atomoxetine. J Clin Psychopharmacol 2004; 24: 567–8PubMed
50.
go back to reference Henderson TA, Hartman K. Aggression, mania, and hypomania induction associated with atomoxetine. Pediatrics 2004; 114: 895–6PubMed Henderson TA, Hartman K. Aggression, mania, and hypomania induction associated with atomoxetine. Pediatrics 2004; 114: 895–6PubMed
51.
go back to reference Hah M, Chang K. Atomoxetine for the treatment of attention-deficit/hyperactivity disorder in children and adolescents with bipolar disorders. J Child Adolesc Psychopharmacol 2005; 15: 996–1004PubMed Hah M, Chang K. Atomoxetine for the treatment of attention-deficit/hyperactivity disorder in children and adolescents with bipolar disorders. J Child Adolesc Psychopharmacol 2005; 15: 996–1004PubMed
52.
go back to reference Scheffer RE, Kowatch RA, Carmody T, et al. Randomized, placebo-controlled trial of mixed amphetamine salts for symptoms of comorbid ADHD in pediatric bipolar disorder after mood stabilization with divalproex sodium. Am J Psychiatry 2005; 162: 58–64PubMed Scheffer RE, Kowatch RA, Carmody T, et al. Randomized, placebo-controlled trial of mixed amphetamine salts for symptoms of comorbid ADHD in pediatric bipolar disorder after mood stabilization with divalproex sodium. Am J Psychiatry 2005; 162: 58–64PubMed
53.
go back to reference Galanter CA, Carlson GA, Jensen PS, et al. Response to methylphenidate in children with attention deficit hyperactivity disorder and manic symptoms in the multimodal treatment study of children with attention deficit hyperactivity disorder titration trial. J Child Adolesc Psychopharmacol 2003; 13: 123–36PubMed Galanter CA, Carlson GA, Jensen PS, et al. Response to methylphenidate in children with attention deficit hyperactivity disorder and manic symptoms in the multimodal treatment study of children with attention deficit hyperactivity disorder titration trial. J Child Adolesc Psychopharmacol 2003; 13: 123–36PubMed
54.
go back to reference Findling RL, Short EJ, Manos MJ. Short-term cardiovascular effects of methylphenidate and adderall. J Am Acad Child Adolesc Psychiatry 2001; 40: 525–9PubMed Findling RL, Short EJ, Manos MJ. Short-term cardiovascular effects of methylphenidate and adderall. J Am Acad Child Adolesc Psychiatry 2001; 40: 525–9PubMed
55.
go back to reference Gutgesell H, Atkins D, Barst R, et al. Cardiovascular monitoring of children and adolescents receiving psychotropic drugs: a statement for healthcare professionals from the Committee on Congenital Cardiac Defects, Council on Cardiovascular Disease in the Young, American Heart Association. Circulation 1999; 99: 979–82PubMed Gutgesell H, Atkins D, Barst R, et al. Cardiovascular monitoring of children and adolescents receiving psychotropic drugs: a statement for healthcare professionals from the Committee on Congenital Cardiac Defects, Council on Cardiovascular Disease in the Young, American Heart Association. Circulation 1999; 99: 979–82PubMed
Metadata
Title
Pharmacological Management of Attention-Deficit Hyperactivity Disorder in Adolescents
Special Considerations
Author
Prof. Philip Hazell
Publication date
01-01-2007
Publisher
Springer International Publishing
Published in
CNS Drugs / Issue 1/2007
Print ISSN: 1172-7047
Electronic ISSN: 1179-1934
DOI
https://doi.org/10.2165/00023210-200721010-00004

Other articles of this Issue 1/2007

CNS Drugs 1/2007 Go to the issue

Leading Article

Neurotensin Agonists