Published in:
01-11-2013 | Editorials
Pharmacologic intervention for managing uterine atony and related maternal hemorrhage: what is the most effective drug dose?
Author:
Holly A. Muir, MD
Published in:
Canadian Journal of Anesthesia/Journal canadien d'anesthésie
|
Issue 11/2013
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Excerpt
Hemorrhage remains the leading cause of maternal death and accounts for approximately 34% of the 350,000 maternal deaths annually worldwide. About 120,000 deaths annually are attributed to hemorrhage. Overall worldwide, the maternal mortality ratio (MMR) is 260/100,000, with a range from less than five in developed regions to more than 1,200 /100,000 in nations with very low income.
1 In low-income countries, hemorrhage is the leading cause of maternal death; however, the problem remains in developed countries. From 2008-2010, there were 7.8 maternal deaths per 100,000 deliveries annually in Canada.
2 Postpartum hemorrhage (PPH) is currently the third leading cause of maternal death in Canada, with a MMR of 1.6/100,000. In the USA, the MMR is much higher at 21/100,000 deliveries in 2010, up from 13.1 in 2006. In the USA, embolic disease, preeclampsia, and hemorrhage remain leading causes of maternal death. …
