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Journal of Anesthesia
Published in: Journal of Anesthesia 4/2016

01-08-2016 | Editorial

Pharmacokinetics and systemic toxicity of local anesthetics in children

Author: Yutaka Oda

Published in: Journal of Anesthesia | Issue 4/2016

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Excerpt

With the development of ultrasound-guided regional anesthetic techniques, peripheral nerve block has become popular and is being performed safely in an increased number of children. From the point of neuronal toxicity and duration of action, long-acting local anesthetics such as bupivacaine, levobupivacaine and ropivacaine are more frequently used than lidocaine for both neuraxial and peripheral nerve block in children. As these anesthetics have higher toxic potency than lidocaine, extensive knowledge of their toxicity and pharmacokinetics in children would contribute to avoiding adverse effects and improving the quality of anesthesia practice. …
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Metadata
Title
Pharmacokinetics and systemic toxicity of local anesthetics in children
Author
Yutaka Oda
Publication date
01-08-2016
Publisher
Springer Japan
Published in
Journal of Anesthesia / Issue 4/2016
Print ISSN: 0913-8668
Electronic ISSN: 1438-8359
DOI
https://doi.org/10.1007/s00540-016-2201-6

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