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Published in: BMC Medicine 1/2013

Open Access 01-12-2013 | Review

Personalized medicine in psychiatry: problems and promises

Authors: Uzoezi Ozomaro, Claes Wahlestedt, Charles B Nemeroff

Published in: BMC Medicine | Issue 1/2013

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Abstract

The central theme of personalized medicine is the premise that an individual’s unique physiologic characteristics play a significant role in both disease vulnerability and in response to specific therapies. The major goals of personalized medicine are therefore to predict an individual’s susceptibility to developing an illness, achieve accurate diagnosis, and optimize the most efficient and favorable response to treatment. The goal of achieving personalized medicine in psychiatry is a laudable one, because its attainment should be associated with a marked reduction in morbidity and mortality. In this review, we summarize an illustrative selection of studies that are laying the foundation towards personalizing medicine in major depressive disorder, bipolar disorder, and schizophrenia. In addition, we present emerging applications that are likely to advance personalized medicine in psychiatry, with an emphasis on novel biomarkers and neuroimaging.
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Metadata
Title
Personalized medicine in psychiatry: problems and promises
Authors
Uzoezi Ozomaro
Claes Wahlestedt
Charles B Nemeroff
Publication date
01-12-2013
Publisher
BioMed Central
Published in
BMC Medicine / Issue 1/2013
Electronic ISSN: 1741-7015
DOI
https://doi.org/10.1186/1741-7015-11-132

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