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Health and Quality of Life Outcomes
Published in: Health and Quality of Life Outcomes 1/2020

01-12-2020 | Peritoneal Dialysis | Review

Comparisons of quality of life between patients underwent peritoneal dialysis and hemodialysis: a systematic review and meta-analysis

Authors: Anan Chuasuwan, Siriporn Pooripussarakul, Ammarin Thakkinstian, Atiporn Ingsathit, Oraluck Pattanaprateep

Published in: Health and Quality of Life Outcomes | Issue 1/2020

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Abstract

Objective

End-stage renal disease (ESRD) leads to renal replacement therapy and certainly has an impact on patients’ health-related quality of life (HRQoL). This study aimed to review and compare the HRQoL between peritoneal dialysis (PD) and hemodialysis (HD) patients using the 36-Item Short Form Health Survey (SF-36), EuroQoL-5-dimension (EQ-5D) and the Kidney Disease Quality of Life Instrument (KDQOL).

Methodology

Systematic review was conducted by identify relevant studies through MEDLINE and SCOPUS up to April 2017. Studies were eligible with following criteria: studied in ESRD patients, compare any pair of renal replacement modalities, and reported HRQoL. The unstandardized mean differences (USMD) of HRQoL among modalities were calculated and pooled using a random-effect models if heterogeneity was present, otherwise a fixed-effect model was applied.

Results

A total of twenty-one studies were included with 29,000 participants. Of them, mean age and percent male were 48.1 years and 45.1, respectively. The pooled USMD (95% CI) of SF-36 between PD and HD (base) were 1.86 (0.47, 3.24) and 0.42 (− 1.99, 2.82) for mental component and physical component summary scores, respectively. For EQ-5D, the pooled USMD of utility and visual analogue scale (VAS) score were 0.02 (− 0.06, 0.10) and 3.56 (1.73, 5.39), respectively. The pooled USMD of KDQOL were 9.67 (5.67, 13.68), 6.71 (− 5.92, 19.32) 6.30 (− 0.41, 12.18), 2.35 (− 4.35, 9.04), 2.10 (0.07, 4.13), and 1.21 (− 2.98, 5.40) for burden of kidney disease, work status, effects of kidney disease, quality of social interaction, symptoms, and cognitive function.

Conclusion

Patients with chronic kidney disease (CKD) stage 5 or ESRD treated with PD had better generic HRQoL measured by SF-36 and EQ-5D than HD patients. In addition, PD had higher specific HRQoL by KDQOL than HD patients in subdomain of physical functioning, role limitations due to emotional problems, effects and burden of kidney disease.
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Literature
1.
Altunoglu A, Yavuz D, Canoz MB, et al. Relationship between inflammation and sex hormone profile in female patients receiving different types of renal replacement therapy. Transplant Proc. 2014;46(5):1585–90.PubMedCrossRef
2.
Kostro JZ, Hellmann A, Kobiela J, et al. Quality of life after kidney transplantation: a prospective study. Transplant Proc. 2016;48(1):50–4.PubMedCrossRef
3.
Kovacs AZ, Molnar MZ, Szeifert L, et al. Sleep disorders, depressive symptoms and health-related quality of life--a cross-sectional comparison between kidney transplant recipients and waitlisted patients on maintenance dialysis. Nephrol Dial Transplant. 2011;26(3):1058–65.PubMedCrossRef
4.
Kalender B, Ozdemir AC, Dervisoglu E, et al. Quality of life in chronic kidney disease: effects of treatment modality, depression, malnutrition and inflammation. Int J Clin Pract. 2007;61(4):569–76.PubMedCrossRef
5.
6.
7.
Valderrabano F, Jofre R, Lopez-Gomez JM. Quality of life in end-stage renal disease patients. Am J Kidney Dis. 2001;38(3):443–64.PubMedCrossRef
8.
Abdel-Kader K, Myaskovsky L, Karpov I, et al. Individual quality of life in chronic kidney disease: influence of age and dialysis modality. Clin J Am Soc Nephrol. 2009;4(4):711–8.PubMedPubMedCentralCrossRef
9.
Laudański K, Nowak Z, Niemczyk S. Age-related differences in the quality of life in end-stage renal disease in patients enrolled in hemodialysis or continuous peritoneal dialysis. Med Sci Monit. 2013;19(1):378–85.PubMedPubMedCentral
10.
Merkus MP, Jager KJ, Dekker FW, et al. Quality of life over time in dialysis: the Netherlands cooperative study on the adequacy of Dialysis. NECOSAD Study Group. Kidney Int. 1999;56(2):720–8.PubMedCrossRef
11.
Rambod M, Shabani M, Shokrpour N, et al. Quality of life of hemodialysis and renal transplantation patients. Health Care Manager. 2011;30(1):23–8.PubMedCrossRef
12.
Peipert JD, Bentler PM, Klicko K, et al. Psychometric properties of the Kidney Disease Quality of Life 36-Item Short-Form Survey (KDQOL-36) in the United States. Am J Kidney Dis. 2018;71(4):461–468.
13.
United States Renal Data System. 2016 annual data report: epidemiology of kidney disease in the United States. Bethesda: National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases; 2016. https://​www.​usrds.​org.
14.
Yang F, Griva K, Lau T, et al. Health-related quality of life of Asian patients with end-stage renal disease (ESRD) in Singapore. Qual Life Res. 2015;24(9):2163–71.PubMedCrossRef
15.
Merkus MP, Jager KJ, Dekker FW, et al. Quality of life in patients on chronic dialysis: self-assessment 3 months after the start of treatment. Am J Kidney Dis. 1997;29(4):584–92.PubMedCrossRef
16.
Ricardo AC, Hacker E, Lora CM, et al. Validation of the kidney disease quality of life short form 36 (KDQOL-36™) US Spanish and English versions in a cohort of Hispanics with chronic kidney disease. Ethn Dis. 2013;23(2):202–9.PubMed
17.
18.
Kontodimopoulos N, Pappa E, Niakas D. Gender- and age-related benefit of renal replacement therapy on health-related quality of life. Scand J Caring Sci. 2009;23(4):721–9.PubMedCrossRef
19.
Bjorner JB, Wolden ML, Gundgaard J, et al. Benchmarks for interpretation of score differences on the SF-36 health survey for patients with diabetes. Value Health. 2013;16:993–1000.PubMedCrossRef
20.
Wee HL, Cheung YB, Li SC, et al. The impact of diabetes mellitus and other chronic medical conditions on health-related quality of life: is the whole greater than the sum of its parts? Health Qual Life Outcomes. 2005;3:2.PubMedPubMedCentralCrossRef
21.
Trevisol DJ, Moreira LB, Kerkhoff A, et al. Health-related quality of life and hypertension: a systematic review and meta-analysis of observational studies. J Hypertens. 2011;29(2):179–88.PubMedCrossRef
22.
Ware JE, Snow KK, Kosinski M, et al. SF-36 health survey: manual and interpretation guide. the Health Institute, New England Medical Center, Placed Published: 1993.
23.
24.
Tonelli M, Wiebe N, Knoll G, et al. Systematic review: kidney transplantation compared with dialysis in clinically relevant outcomes. Am J Transplant. 2011;11(10):2093–109.PubMedCrossRef
25.
Evans RW, Manninen DL, Garrison LP Jr, et al. The quality of life of patients with end-stage renal disease. N Engl J Med. 1985;312(9):553–9.PubMedCrossRef
26.
Lee AJ, Morgan CL, Conway P, et al. Characterisation and comparison of health-related quality of life for patients with renal failure. Curr Med Res Opin. 2005;21(11):1777–83.PubMedCrossRef
27.
Makkar V, Kumar M, Mahajan R, et al. Comparison of outcomes and quality of life between hemodialysis and peritoneal dialysis patients in indian ESRD population. J Clin Diagn Res. 2015;9(3):28–31.
28.
Boateng EA, East L. The impact of dialysis modality on quality of life: a systematic review. J Ren Care. 2011;37(4):190–200.PubMedCrossRef
29.
Liem YS, Bosch JL, Myriam Hunink MG. Preference-based quality of life of patients on renal replacement therapy: a systematic review and meta-analysis. Value Health. 2008;11(4):733–41.PubMedCrossRef
30.
31.
32.
33.
Farivar SS, Cunningham WE, Hays R. Correlated physical and mental health summary scores for the SF-36 and SF-12 Health Survey, V.1. Health Qual Life Outcomes. 2007;5:54.PubMedPubMedCentralCrossRef
34.
35.
Hays RD, Kallich JD, Mapes DL, et al. Development of the kidney disease quality of life (KDQOL) instrument. Qual Life Res. 1994;3(5):329–38.PubMedCrossRef
36.
Hay RD, Kallich JD, Mapes DL, et al. Kidney disease quality of life short form (KDQOL-SF™), version 1.3: a manual for use and scoring. CA: RAND, Santa Monica; 1997.
37.
38.
39.
Herzog R, Alvarez-Pasquin MJ, Diaz C, et al. Are healthcare workers' intentions to vaccinate related to their knowledge, beliefs and attitudes? A systematic review. BMC Public Health. 2013;13:154.PubMedPubMedCentralCrossRef
40.
Wight JP, Edwards L, Brazier J, et al. The SF36 as an outcome measure of services for end stage renal failure. Quality in Health Care. 1998;7(4):209–21.PubMedCrossRefPubMedCentral
41.
Blake C, Codd MB, Cassidy A, et al. Physical function, employment and quality of life in end-stage renal disease. J Nephrol. 2000;13(2):142–9.PubMed
42.
Diaz-Buxo JA, Lowrie EG, Lew NL, et al. Quality-of-life evaluation using short form 36: comparison in hemodialysis and peritoneal dialysis patients. Am J Kidney Dis. 2000;35(2):293–300.PubMedCrossRef
43.
Harris SA, Lamping DL, Brown EA, et al. Clinical outcomes and quality of life in elderly patients on peritoneal dialysis versus hemodialysis. Perit Dial Int. 2002;22(4):463–70.PubMedCrossRef
44.
Wasserfallen JB, Halabi G, Saudan P, et al. Quality of life on chronic dialysis: comparison between haemodialysis and peritoneal dialysis. Nephrol Dial Transplant. 2004;19(6):1594–9.PubMedCrossRef
45.
Kutner NG, Zhang R, Brogan D. Race, gender, and incident dialysis patients' reported health status and quality of life. J Am Soc Nephrol. 2005;16(5):1440–8.PubMedCrossRef
46.
Zhang AH, Cheng LT, Zhu N, et al. Comparison of quality of life and causes of hospitalization between hemodialysis and peritoneal dialysis patients in China. Health Qual Life Outcomes. 2007;5:49.PubMedPubMedCentralCrossRef
47.
Sayin A, Mutluay R, Sindel S. Quality of life in hemodialysis, peritoneal dialysis, and transplantation patients. Transplant Proc. 2007;39(10):3047–53.PubMedCrossRef
48.
Borowiak E, Braksator E, Nowicki M, et al. Quality of life of chronic hemodialysis and peritoneal dialysis patients. Clin Exp Med Lett. 2009;50(1):37–42.
49.
Ibrahim N, Chiew-Tong NK, Desa A. Symptoms and health-related quality of life in patients with heamodialysis and continuous ambulatory peritoneal dialysis. Res J Med Sci. 2011;5(5):252–6.CrossRef
50.
Turkmen K, Yazici R, Solak Y, et al. Health-related quality of life, sleep quality, and depression in peritoneal dialysis and hemodialysis patients. Hemodial Int. 2012;16(2):198–206.PubMedCrossRef
51.
Okpechi IG, Nthite T, Swanepoel CR. Health-related quality of life in patients on hemodialysis and peritoneal dialysis. Saudi J Kidney Dis Transpl. 2013;24(3):519–26.PubMedCrossRef
52.
Czyzewski L, Sanko-Resmer J, Wyzgal J, et al. Assessment of health-related quality of life of patients after kidney transplantation in comparison with hemodialysis and peritoneal dialysis. Ann Transplant. 2014;19:576–85.PubMedCrossRef
53.
Chang YT, Hwang JS, Hung SY, et al. Cost-effectiveness of hemodialysis and peritoneal dialysis: a national cohort study with 14 years follow-up and matched for comorbidities and propensity score. Sci Rep. 2016;6:30266.PubMedPubMedCentralCrossRef
54.
Johnston BC, Thorlund K, Schunemann HJ, et al. Improving the interpretation of quality of life evidence in meta-analyses: the application of minimal important difference units. Health Qual Life Outcomes. 2010;8:116.PubMedPubMedCentralCrossRef
55.
Ringash J, O'Sullivan B, Bezjak A, et al. Interpreting clinically significant changes in patient-reported outcomes. Cancer. 2007;110:196–202.PubMedCrossRef
56.
Wyrwich KW, Tierney WM, Wolinsky FD. Further Evidence Supporting an SEM-Based Criterion for Identifying Meaningful Intra-Individual Changes in Health-Related Quality of Life. Journal of Clinical Epidemiology 1999;52(9):861–873.
57.
Contopoulos-Ioannidis DG, Karvouni A, Kouri I, et al. Reporting and interpretation of SF-36 outcomes in randomised trials: systematic review. BMJ. 2009;339:a3006.CrossRef
58.
Liem YS, Bosch JL, Arends LR, et al. Quality of life assessed with the medical outcomes study short form 36-item health survey of patients on renal replacement therapy: a systematic review and meta-analysis. Value Health. 2007;10(5):390–7.PubMedCrossRef
59.
Zazzeroni L, Pasquinelli G, Nanni E, et al. Comparison of quality of life in patients undergoing hemodialysis and peritoneal Dialysis: a systematic review and meta-analysis. Kidney Blood Press Res. 2017;42(4):717–27.PubMedCrossRef
60.
Rasanen P, Roine E, Sintonen H, et al. Use of quality-adjusted life years for the estimation of effectiveness of health care: a systematic literature review. Int J Technol Assess Health Care. 2006;22(2):235–41.PubMedCrossRef
61.
Sakthong P, Kasemsup V. Health utility measured with EQ-5D in Thai patients undergoing peritoneal dialysis. Value Health. 2012;15(1 Suppl):S79–84.PubMedCrossRef
62.
63.
Cameron JI, Whiteside C, Katz J, et al. Differences in quality of life across renal replacement therapies: a meta-analytic comparison. Am J Kidney Dis. 2000;35(4):629–37.PubMedCrossRef
64.
Chang TI, Tamura MK. Chapter 35 : Methods to Assess Quality of Life and Functional Status and Their Applications in Clinical Care in Elderly Patients with CKD. Conference Proceedings; 2009.
65.
Detmar SB, Muller MJ, Schornagel JH, et al. Health-related quality-of-life assessments and patient-physician communication: a randomized controlled trial. Jama. 2002;288(23):3027–34.PubMedCrossRef
66.
Ginieri-Coccossis M, Theofilou P, Synodinou C, et al. Quality of life, mental health and health beliefs in haemodialysis and peritoneal dialysis patients: Investigating differences in early and later years of current treatment. BMC Nephrol. 2008;9(1):14. https://​doi.​org/​10.​1186/​1471-2369-9-14.
67.
Greenfield S, Sullivan L, Silliman RA, et al. Principles and practice of case mix adjustment: applications to end-stage renal disease. Am J Kidney Dis. 1994;24(2):298–307.PubMedCrossRef
68.
Valderrabano F. Quality of life benefits of early anaemia treatment. Nephrol Dial Transplant. 2000;15(Suppl 3):23–8.PubMedCrossRef
69.
Unruh M, Benz R, Greene T, et al. Effects of hemodialysis dose and membrane flux on health-related quality of life in the HEMO study. Kidney Int. 2004;66(1):355–66.PubMedCrossRef
70.
Shrestha S, Ghotekar LR, Sharma SK, et al. Assessment of quality of life in patients of end stage renal disease on different modalities of treatment. J Nepal Med Assoc. 2008;47(169):1–6.
Metadata
Title
Comparisons of quality of life between patients underwent peritoneal dialysis and hemodialysis: a systematic review and meta-analysis
Authors
Anan Chuasuwan
Siriporn Pooripussarakul
Ammarin Thakkinstian
Atiporn Ingsathit
Oraluck Pattanaprateep
Publication date
01-12-2020
Publisher
BioMed Central
Published in
Health and Quality of Life Outcomes / Issue 1/2020
Electronic ISSN: 1477-7525
DOI
https://doi.org/10.1186/s12955-020-01449-2

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