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Child's Nervous System

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01-06-2018 | Original Paper

Peripheral nervous system maturation in preterm infants: longitudinal motor and sensory nerve conduction studies

Authors: S. Lori, Giovanna Bertini, M. Bastianelli, S. Gabbanini, D. Gualandi, E. Molesti, C. Dani

Published in: Child's Nervous System | Issue 6/2018

Abstract

Objective

To study the evolution of sensory-motor nerves in the upper and lower limbs in neurologically healthy preterm infants and to use sensory-motor studies to compare the rate of maturation in preterm infants at term age and full-term healthy neonates.

Methods

The study comprised 26 neurologically normal preterm infants born at 23–33 weeks of gestational age, who underwent sensory nerve conduction and motor nerve conduction studies from plantar medial and median nerves and from tibial and ulnar nerves, respectively. We repeated the same neurophysiological studies in 19 of the preterm infants every 2 weeks until postnatal term age. The data from the preterm infants at term was matched with a group of ten full-term babies a few days after birth.

Results

The motor nerve conduction velocity of the tibial and ulnar nerves showed progressive increases in values in relation to gestational age, but there was a decrease of values in distal latencies and F wave latencies. Similarly, there was a gradual increase of sensory nerve conduction velocity values of the medial plantar and median nerves and decreases in latencies in relation to gestational age. At term age, the preterm infants showed significantly lower values of conduction velocities and distal latencies than the full-term neonates. These results were probably because the preterm infants had significantly lower weights, total length and, in particular, distal segments of the limbs at term age.

Conclusion

The sensory-motor conduction parameters were clearly related to gestational age, but extrauterine life did not affect the maturation of the peripheral nervous system in the very preterm babies who were neurologically healthy.

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Title: Peripheral nervous system maturation in preterm infants: longitudinal motor and sensory nerve conduction studies
Authors: S. Lori
Giovanna Bertini
M. Bastianelli
S. Gabbanini
D. Gualandi
E. Molesti
C. Dani
Publication date: 01-06-2018
Publisher: Springer Berlin Heidelberg
Published in: Child's Nervous System / Issue 6/2018
Print ISSN: 0256-7040
Electronic ISSN: 1433-0350
DOI: https://doi.org/10.1007/s00381-018-3778-x

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Peripheral nervous system maturation in preterm infants: longitudinal motor and sensory nerve conduction studies

Abstract

Objective

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objective

Methods

Results

Conclusion

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