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BMC Pregnancy and Childbirth
Published in: BMC Pregnancy and Childbirth 1/2016

Open Access 01-12-2016 | Research article

Perinatal maternal depression and cortisol function in pregnancy and the postpartum period: a systematic literature review

Authors: Sunaina Seth, Andrew J. Lewis, Megan Galbally

Published in: BMC Pregnancy and Childbirth | Issue 1/2016

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Abstract

Background

Perinatal depression has a significant impact on both mother and child. However, the influence of hormonal changes during pregnancy and the postpartum period remains unclear. This article provides a systematic review of studies examining the effects of maternal cortisol function on perinatal depression.

Method

A systematic search was conducted of six electronic databases for published research on the relationship between cortisol and perinatal depression. The databases included; MEDLINE complete, PsychINFO, SCOPUS, Psychology and Behavioural Sciences, Science Direct and EBSCO, for the years 1960 to May 2015. Risk of bias was assessed and data extraction verified by two investigators.

Results

In total, 47 studies met criteria and studies showed considerable variation in terms of methodology including sample size, cortisol assays, cortisol substrates, sampling processes and outcome measures. Those studies identified as higher quality found that the cortisol awakening response is positively associated with momentary mood states but is blunted in cases of major maternal depression. Furthermore, results indicate that hypercortisolemia is linked to transient depressive states while hypocortisolemia is related to chronic postpartum depression.

Discussion and Conclusion

Future research should aim to improve the accuracy of cortisol measurement over time, obtain multiple cortisol samples in a day and utilise diagnostic measures of depression. Future studies should also consider both antenatal and postnatal depression and the differential impact of atypical versus melancholic depression on cortisol levels, as this can help to further clarify the relationship between perinatal depression and maternal cortisol function across pregnancy and the postpartum period.
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Literature
1.
2.
Taylor A, Glover V, Marks M, Kammerer M. Diurnal pattern of cortisol output in postnatal depression. Psychoneuroendocrinology. 2009;34(8):1184–8.CrossRefPubMed
3.
Lewis AJ, Galbally M. Review: adverse effects of antidepressants use during pregnancy. Evid Based Ment Health. 2011;14(2):40.CrossRefPubMed
4.
Lewis AJ, Galbally M, Bailey CM. Perinatal mental health, antidepressants and neonatal outcomes: findings from the Longitudinal Study of Australian Children. Neonatal Paediatr Child Health Nurs. 2012;15(3):21.
5.
Galbally M, Lewis AJ, Ijzendoorn M, Permezel M. The role of oxytocin in mother-infant relations: a systematic review of human studies. Harv Rev Psychiatry. 2011;19(1):1–14.CrossRefPubMed
6.
Seth S, Lewis AJ, Saffery R, Lappas M, Galbally M. Maternal Prenatal Mental Health and Placental 11beta-HSD2 Gene Expression: Initial Findings from the Mercy Pregnancy and Emotional Wellbeing Study. Int J Mol Sci. 2015;16(11):27482–96.CrossRefPubMedPubMedCentral
7.
Lewis A, Austin E, Knapp R, Vaiano T, Galbally M. Perinatal Maternal Mental Health, Fetal Programming and Child Development. Healthcare. 2015;3(4):1212.CrossRef
8.
Brummelte S, Galea LAM. Depression during pregnancy and postpartum: Contribution of stress and ovarian hormones. Prog Neuro-Psychopharmacol Biol Psychiatry. 2010;34(5):766–76.CrossRef
9.
Brummelte S, Schmidt KL, Taves MD, Soma KK, Galea LAM. Elevated corticosterone levels in stomach milk, serum, and brain of male and female offspring after maternal corticosterone treatment in the rat. Dev Neurobiol. 2010;70(10):714–25.CrossRefPubMed
10.
Leinonen JA, Solantaus TS, Punamaki RL. Parental mental health and children’s adjustment: the quality of marital interaction and parenting as mediating factors. J Child Psychol Psychiatry. 2003;44(2):227–41.CrossRefPubMed
11.
Goodman SH, Rouse MH, Long Q, Ji S, Brand SR. Deconstructing antenatal depression: What is it that matters for neonatal behavioral functioning? Infant Ment Health J. 2011;32(3):339–61.CrossRef
12.
Gaynes BN, Gavin N, Meltzer-Brody S, Lohr KN, Swinson T, Gartlehner G, et al. Perinatal depression: prevalence, screening accuracy, and screening outcomes. Evid Rep Technol Assess (Summ). 2005;119:1–8.
13.
Lewis AJ, Austin E, Galbally M. Prenatal maternal mental health and fetal growth restriction: a systematic review. J Dev Origins Health Dis. 2016;17:1–13.CrossRef
14.
Murray L, Arteche A, Fearon P, Halligan S, Goodyer I, Cooper P. Maternal postnatal depression and the development of depression in offspring up to 16 years of age. J Am Acad Child Adolesc Psychiatry. 2011;50(5):460–70.CrossRefPubMed
15.
Lewis AJ. Depression in Pregnancy and Child Development: Understanding the Mechanisms of Transmission. In: Galbally M, Snellen M, Lewis A, editors. Psychopharmacology and Pregnancy: Treatment Efficacy, Risks, and Guidelines. Berlin, Heidelberg: Springer Berlin Heidelberg; 2014. p. 47–65.
16.
Lancaster CA, Gold KJ, Flynn HA, Yoo H, Marcus SM, Davis MM. Risk factors for depressive symptoms during pregnancy: a systematic review. Am J Obstet Gynecol. 2010;202(1):5–14.CrossRefPubMedPubMedCentral
17.
Obel C, Hedegaard M, Henriksen TB, Secher NJ, Olsen J, Levine S. Stress and salivary cortisol during pregnancy. Psychoneuroendocrinology. 2005;30(7):647–56.CrossRefPubMed
18.
Tsigos C, Chrousos GP. Hypothalamic–pituitary–adrenal axis, neuroendocrine factors and stress. J Psychosom Res. 2002;53(4):865–71.CrossRefPubMed
19.
Kammerer M, Taylor A, Glover V. The HPA axis and perinatal depression: a hypothesis. Arch Womens Ment Health. 2006;9(4):187–96.CrossRefPubMed
20.
de Kloet ER, Joëls M, Holsboer F. Stress and the brain: from adaptation to disease. Nat Rev Neurosci. 2005;6(6):463–75.CrossRefPubMed
21.
Pariante CM. The glucocorticoid receptor: part of the solution or part of the problem? J Psychopharmacol. 2006;20(4 Suppl):79–84.CrossRefPubMed
22.
Penninx BWJH, Milaneschi Y, Lamers F, Vogelzangs N. Understanding the somatic consequences of depression: biological mechanisms and the role of depression symptom profile. BMC Med. 2013;11:129–9.
23.
Campbell EA, Linton EA, Wolfe CD, Scraggs PR, Jones MT, Lowry PJ. Plasma corticotropin-releasing hormone concentrations during pregnancy and parturition. J Clin Endocrinol Metab. 1987;64(5):1054–9.CrossRefPubMed
24.
Kammerer M, Adams D, Castelberg BV, Glover V. Pregnant women become insensitive to cold stress. BMC Pregnancy Childbirth. 2002;2(1):1–5.CrossRef
25.
Brunton PJ, Russell JA, Douglas AJ. Adaptive responses of the maternal hypothalamic-pituitary-adrenal axis during pregnancy and lactation. J Neuroendocrinol. 2008;20(6):764–76.CrossRefPubMed
26.
Houshyar H, Galigniana MD, Pratt WB, Woods JH. Differential responsivity of the hypothalamic-pituitary-adrenal axis to glucocorticoid negative-feedback and corticotropin releasing hormone in rats undergoing morphine withdrawal: possible mechanisms involved in facilitated and attenuated stress responses. J Neuroendocrinol. 2001;13(10):875–86.CrossRefPubMed
27.
28.
Workman JL, Barha CK, Galea LAM. Endocrine substrates of cognitive and affective changes during pregnancy and postpartum. Behav Neurosci. 2012;126(1):54–72.CrossRefPubMed
29.
30.
Piazza PV, Rouge-Pont F, Deroche V, Maccari S, Simon H, Moal ML. Glucocorticoids have a state-dependent stimulant effects on the mesencephalic dopaminergic transmission. Proc Natl Acad Sci U S A. 1996;16:8716.CrossRef
31.
Posener JA, Schatzberg AF, Williams GH, Samson JA, McHale NL, Bessette MP, et al. Hypothalamic-pituitary-adrenal axis effects on plasma homovanillic acid in man. Biol Psychiatry. 1999;45(2):222–8.
32.
Barrot M, Abrous DN, Marinelli M, Rougé-Pont F, Le Moal M, Piazza PV. Influence of glucocorticoids on dopaminergic transmission in the rat dorsolateral striatum. Eur J Neurosci. 2001;13(4):812–8.CrossRefPubMed
33.
Levine A, Zagoory-Sharon O, Feldman R, Lewis JG, Weller A. Measuring cortisol in human psychobiological studies. Physiol Behav. 2007;90(1):43–53.CrossRefPubMed
34.
Pruessner JC, Wolf OT, Hellhammer DH, Buske-Kirschbaum A, von Auer K, Jobst S, et al. Free cortisol levels after awakening: a reliable biological marker for the assessment of adrenocortical activity. Life Sci. 1997;61(26):2539–49.
35.
Kirschbaum C, Hellhammer DH. Salivary cortisol in psychobiological research: an overview. Neuropsychobiology. 1989;22(3):150–69.CrossRefPubMed
36.
Jung C, Greco S, Nguyen HHT, Ho JT, Lewis JG, Torpy DJ, et al. Plasma, salivary and urinary cortisol levels following physiological and stress doses of hydrocortisone in normal volunteers. BMC Endocr Disord. 2014;14(1):61–80.
37.
Kendell RE. Emotional and physical factors in the genesis of puerperal mental disorders. J Psychosom Res. 1985;29(1):3–11.CrossRefPubMed
38.
Wieck A. 10 Endocrine aspects of postnatal mental disorders. Baillieres Clin Obstet Gynaecol. 1989;3(4):857–77.CrossRefPubMed
39.
Smith R, Thomson M. 10 Neuroendocrinology of the hypothalamo-pituitary-adrenal axis in pregnancy and the puerperium. Bailliere Clin Endocrinol Metab. 1991;5(1):167–86.CrossRef
40.
Harris B. Hormonal aspects of postnatal depression. Int Rev Psychiatry. 1996;8(1):27–36.CrossRef
41.
Hendrick V, Altshuler LL, Suri R. Hormonal changes in the postpartum and implications for postpartum depression. Psychosomatics. 1998;39(2):93–101.CrossRefPubMed
42.
Breese McCoy SJ, Beal JM, Watson GH. Endocrine factors and postpartum depression: a selected review. J Reprod Med. 2003;48(6):402–8.
43.
Glynn LM, Davis EP, Sandman CA. New insights into the role of perinatal HPA-axis dysregulation in postpartum depression. Neuropeptides. 2013;47(6):363–70.CrossRefPubMed
44.
Handley SL, Dunn TL, Waldron G, Baker JM. Tryptophan, cortisol and puerperal mood. Br J Psychiatry. 1980;136:498–508.CrossRefPubMed
45.
Smith R, Cubis J, Brinsmead M, Lewin T, Singh B, Owens P, et al. Mood changes, obstetric experience and alterations in plasma cortisol, beta-endorphin and corticotrophin releasing hormone during pregnancy and the puerperium. J Psychosom Res. 1990;34(1):53–69.
46.
O’Hara MW, Schlechte JA, Lewis DA, Wright EJ. Prospective study of postpartum blues. Biologic and psychosocial factors. Arch Gen Psychiatry. 1991;48(9):801–6.CrossRefPubMed
47.
Harris B, Lovett L, Smith J, Read G, Walker R, Newcombe RG. Cardiff Puerpreral Mood and Hormone Study: III. Postnatal depression at 5 to 6 weeks postpartum, and its hormonal correlates across the peripartum period. Br J Psychiatry. 1996;168(6):739–444.CrossRefPubMed
48.
Harris B, Johns S, Fung H, Thomas R, Walker R, Read G, et al. The hormonal environment of post-natal depression. Br J Psychiatry. 1989;154:660–7.
49.
Gard PR, Handley SL, Parsons AD, Waldron G. A multivariate investigation of postpartum mood disturbance. Br J Psychiatry. 1986;148:567–75.CrossRefPubMed
50.
Pedersen CA, Stern RA, Pate J, Senger MA, Bowes WA, Mason GA. Thyroid and adrenal measures during late pregnancy and the puerperium in women who have been major depressed or who become dysphoric postpartum. J Affect Disord. 1993;29(2-3):201–11.CrossRefPubMed
51.
Magiakou MA, Mastorakos G, Rabin D, Dubbert B, Gold PW, Chrousos GP. Hypothalamic corticotropin-releasing hormone suppression during the postpartum period: implications for the increase in psychiatric manifestations at this time. J Clin Endocrinol Metab. 1996;81(5):1912–7.PubMed
52.
Okano T, Nomura J. Endocrine study of the maternity blues. Prog Neuro-Psychopharmacol Biol Psychiatry. 1992;16(6):921–32.CrossRef
53.
Parry BL, Sorenson DL, Meliska CJ, Basavaraj N, Zirpoli GG, Gamst A, et al. Hormonal basis of mood and postpartum disorders. Curr Womens Health Rep. 2003;3(3):230–5.
54.
Groer MW, Morgan K. Immune, health and endocrine characteristics of depressed postpartum mothers. Psychoneuroendocrinology. 2007;32(2):133–9.CrossRefPubMed
55.
Borenstein M, Hedges LV, Higgins JPT, Rothstein HR. Front Matter. In: Introduction to Meta-Analysis. edn.: West Sussex, UK: John Wiley & Sons, Ltd; 2009. i-xxix.
56.
Lundy BL, Jones NA, Field T, Nearing G, Davalos M, Pietro PA, et al. Prenatal depression effects on neonates. Infant Behav Dev. 1999;22(1):119–29.
57.
Field T, Diego M, Dieter J, Hernandez-Reif M, Schanberg S, Kuhn C, et al. Prenatal depression effects on the fetus and the newborn. Infant Behav Dev. 2004;27(2):216–29.
58.
Field T, Hernandez-Reif M, Diego M, Figueiredo B, Schanberg S, Kuhn C. Prenatal cortisol, prematurity and low birthweight. Infant Behav Dev. 2006;29(2):268–75.CrossRefPubMed
59.
Field T, Diego MA, Hernandez-Reif M, Figueiredo B, Ascencio A, Schanberg S, et al. Prenatal dysthymia versus major depression effects on maternal cortisol and fetal growth. Depress Anxiety. 2008;25(6):E11–16.
60.
Parcells DA. Women’s mental health nursing: depression, anxiety and stress during pregnancy. J Psychiatr Ment Health Nurs. 2010;17(9):813–20.CrossRefPubMed
61.
Giesbrecht GF, Campbell T, Letourneau N, Kooistra L, Kaplan B. Psychological distress and salivary cortisol covary within persons during pregnancy. Psychoneuroendocrinology. 2012;37(2):270–9.CrossRefPubMed
62.
O’Connor TG, Tang W, Gilchrist MA, Moynihan JA, Pressman EK, Blackmore ER. Diurnal cortisol patterns and psychiatric symptoms in pregnancy: short-term longitudinal study. Biol Psychol. 2014;96:35–41.CrossRefPubMed
63.
Diego MA, Field T, Hernandez-Reif M, Schanberg S, Kuhn C, Gonzalez-Quintero VH. Prenatal depression restricts fetal growth. Early Hum Dev. 2009;85(1):65–70.CrossRefPubMedPubMedCentral
64.
Voegtline KM, Costigan KA, Kivlighan KT, Laudenslager ML, Henderson JL, DiPietro JA. Concurrent levels of maternal salivary cortisol are unrelated to self-reported psychological measures in low-risk pregnant women. Arch Womens Ment Health. 2013;16(2):101–8.CrossRefPubMedPubMedCentral
65.
Nierop A, Bratsikas A, Zimmermann R, Ehlert U. Are stress-induced cortisol changes during pregnancy associated with postpartum depressive symptoms? Psychosom Med. 2006;68(6):931–7.CrossRefPubMed
66.
Evans LM, Myers MM, Monk C. Pregnant women’s cortisol is elevated with anxiety and depression--But only when comorbid. Arch Womens Ment Health. 2008;11(3):239–48.CrossRefPubMedPubMedCentral
67.
Cheng CY, Pickler RH. Maternal psychological well-being and salivary cortisol in late pregnancy and early post-partum. Stress Health. 2010;26(3):215–24.CrossRef
68.
Pluess M, Bolten M, Pirke K-M, Hellhammer D. Maternal trait anxiety, emotional distress, and salivary cortisol in pregnancy. Biol Psychol. 2010;83(3):169–75.CrossRefPubMed
69.
Peer M, Soares CN, Levitan RD, Streiner DL, Steiner M. Antenatal depression in a multi-ethnic, community sample of Canadian immigrants: psychosocial correlates and hypothalamic-pituitary-adrenal axis function. Can J Psychiatry. 2013;58(10):579–87.PubMed
70.
Handley SL, Dunn TL, Baker JM, Cockshott C, Gould S. Mood changes in puerperium, and plasma tryptophan and cortisol concentrations. Br Med J. 1977;2(6078):18–20.CrossRefPubMedPubMedCentral
71.
Ehlert U, Patalla U, Kirschbaum C, Piedmont E, Hellhammer DH. Postpartum blues: salivary cortisol and psychological factors. J Psychosom Res. 1990;34(3):319–25.CrossRefPubMed
72.
Okano T, Nomura J. Endocrine study of the maternity blues. Prog Neuropsychopharmacol Biol Psychiatry. 1992;16(6):921–32.CrossRefPubMed
73.
Taylor A, Littlewood J, Adams D, Doré C, Glover V. Serum cortisol levels are related to moods of elation and dysphoria in new mothers. Psychiatry Res. 1994;54(3):241–7.CrossRefPubMed
74.
Balbi C, D’Ajello M, Acerra M. Blood cortisol and puerperal depression. Archivio di Ostetricia e Ginecologia. 1980;85(3):199–202.PubMed
75.
Kuevi V, Causon R, Dixson AF, Everard DM, Hall JM, Hole D, et al. Plasma amine and hormone changes in ‘post-partum blues’. Clin Endocrinol. 1983;19(1):39–46.
76.
Brinsmead M, Smith R, Singh B, Lewin T, Owens P. Peripartum concentrations of beta endorphin and cortisol and maternal mood states. Aust N Z J Obstet Gynaecol. 1985;25(3):194–7.CrossRefPubMed
77.
Feksi A, Harris B, Walker R, Riad-Fahmy D, Newcombe RG. ‘Maternity blues’ and hormone levels in saliva. J Affect Disord. 1984;6(3-4):351–5.CrossRefPubMed
78.
Harris B, Lovett L, Newcombe RG, Read GF, Walker R, Riad-Fahmy D. Maternity blues and major endocrine changes: Cardiff puerperal mood and hormone study II. Br Med J. 1994;308(6934):949–53.CrossRef
79.
Abou-Saleh MT, Ghubash R, Karim L, Krymski M, Bhai I. Hormonal aspects of postpartum depression. Psychoneuroendocrinology. 1998;23(5):465–75.CrossRefPubMed
80.
Susman EJ, Schmeelk KH, Worrall BK, Granger DA, Ponirakis A, Chrousos GP. Corticotropin-releasing hormone and cortisol: Longitudinal associations with depression and antisocial behavior in pregnant adolescents. J Am Acad Child Adolesc Psychiatry. 1999;38(4):460–7.CrossRefPubMed
81.
Davis EP, Glynn LM, Schetter CD, Hobel C, Chicz-Demet A, Sandman CA. Prenatal exposure to maternal depression and cortisol influences infant temperament. J Am Acad Child Adolesc Psychiatry. 2007;46(6):737–46.CrossRefPubMed
82.
Figueiredo B, Costa R. Mother’s stress, mood and emotional involvement with the infant: 3 months before and 3 months after childbirth. Arch Womens Ment Health. 2009;12(3):143–53.CrossRefPubMed
83.
O’Keane V, Lightman S, Patrick K, Marsh M, Papadopoulos AS, Pawlby S, et al. Changes in the maternal hypothalamic‐pituitary‐adrenal axis during the early puerperium may be related to the postpartum ‘blues’. J Neuroendocrinol. 2011;23(11):1149–55.
84.
Tsubouchi H, Nakai Y, Toda M, Morimoto K, Chang YS, Ushioda N, et al. Change of salivary stress marker concentrations during pregnancy: maternal depressive status suppress changes of those levels. J Obstet Gynaecol Res. 2011;37(8):1004–9.
85.
Adam EK, Kumari M. Assessing salivary cortisol in large-scale, epidemiological research. Psychoneuroendocrinology. 2009;34(10):1423–36.CrossRefPubMed
86.
Harris B, Lovett L, Newcombe RG, Read GF, Walker R, Riad-Fahmy D. Maternity blues and major endocrine changes: Cardiff puerperal mood and hormone study II. BMJ. 1994;308(6934):949–53.CrossRefPubMedPubMedCentral
87.
Fan F, Zou Y, Ma A, Yue Y, Mao W, Ma X. Hormonal changes and somatopsychologic manifestations in the first trimester of pregnancy and post partum. Int J Gynecol Obstet. 2009;105(1):46–9.CrossRef
88.
Field T, Diego M, Hernandez-Reif M. Prenatal depression effects on the fetus and newborn: a review. Infant Behav Dev. 2006;29(3):445–55.CrossRefPubMed
89.
Salacz P, Csukly G, Haller J, Valent S. Association between subjective feelings of distress, plasma cortisol, anxiety, and depression in pregnant women. Eur J Obstet Gynecol Reprod Biol. 2012;165(2):225–30.CrossRefPubMed
90.
Mahomed K, Gulmezoĝlu AM, Nikodem VC, Wolman WL, Chalmers BE, Hofmeyr GJ. Labor experience, maternal mood and cortisol and catecholamine levels in low-risk primiparous women. J Psychosom Obstet Gynecol. 1995;16(4):181–6.CrossRef
91.
Luiza JW, Gallaher MJ, Powers RW. Urinary cortisol and depression in early pregnancy: role of adiposity and race. BMC Pregnancy Childbirth. 2015;15(1):30.CrossRefPubMedPubMedCentral
92.
Field T, Diego M. Cortisol: the culprit prenatal stress variable. Int J Neurosci. 2008;118(8):1181.CrossRefPubMed
93.
Yim IS, Glynn LM, Schetter CD, Hobel CJ, Chicz-DeMet A, Sandman CA. Risk of postpartum depressive symptoms with elevated corticotropin-releasing hormone in human pregnancy. Arch Gen Psychiatry. 2009;66(2):162–9.CrossRefPubMedPubMedCentral
94.
Diego MA, Field T, Hernandez-Reif M, Cullen C, Schanberg S, Kuhn C. Prepartum, postpartum, and chronic depression effects on newborns. Psychiatry. 2004;67(1):63–80.CrossRefPubMed
95.
Shelton MM, Schminkey DL, Groer MW. Relationships among prenatal depression, plasma cortisol, and inflammatory cytokines. Biol Res Nurs. 2014;17(3):295–302.CrossRefPubMedPubMedCentral
96.
Raff H, Homar PJ, Burns EA. Comparison of two methods for measuring salivary cortisol. Clin Chem. 2002;48(1):207–8.PubMed
97.
Pearson Murphy BE. Urinary free cortisol determinations: What they measure. Endocrinologist. 2002;12(2):143–50.CrossRef
98.
Schultheiss OC, Stanton, SJ. Assessment of salivary hormones. In: Methods of Social Neuroscience. edn.: New York, US: Guilford Press; 2009. p. 17–44.
99.
100.
101.
Meltzer-Brody S, Stuebe A, Dole N, Savitz D, Rubinow D, Thorp J. Elevated corticotropin releasing hormone (CRH) during pregnancy and risk of postpartum depression (PPD). J Clin Endocrinol Metab. 2011;96(1):E40–47.CrossRefPubMedPubMedCentral
102.
Glover V, Kammerer M. The biology and pathophysiology of peripartum psychiatric disorders. Primary Psychiatry. 2004;11(3):37–41.
103.
Ross LE, Grigoriadis S, Mamisashvili L, Koren G, Steiner M, Dennis CL, et al. Quality assessment of observational studies in psychiatry: an example from perinatal psychiatric research. Int J Methods Psychiatr Res. 2011;20(4):224–34.
104.
Shimizu A, Nishiumi H, Okumura Y, Watanabe K. Depressive symptoms and changes in physiological and social factors 1 week to 4 months postpartum in Japan. J Affect Disord. 2015;179:175–82.CrossRefPubMed
105.
Geracioti Jr TD, Loosen PT, Orth DN. Low cerebrospinal fluid corticotropin-releasing hormone concentrations in eucortisolemic depression. Biol Psychiatry. 1997;42(3):165–74.CrossRefPubMed
106.
Levitan RD, Vaccarino FJ, Brown GM, Kennedy SH. Low-dose dexamethasone challenge in women with atypical major depression: pilot study. J Psychiatry Neurosci. 2002;27(1):47–51.PubMedPubMedCentral
107.
Gold PW, Chrousos GP. Organization of the stress system and its dysregulation in melancholic and atypical depression: high vs low CRH/NE states. Mol Psychiatry. 2002;7(3):254–75.CrossRefPubMed
108.
Fries E, Hesse J, Hellhammer J, Hellhammer DH. A new view on hypocortisolism. Psychoneuroendocrinology. 2005;30(10):1010–6.CrossRefPubMed
Metadata
Title
Perinatal maternal depression and cortisol function in pregnancy and the postpartum period: a systematic literature review
Authors
Sunaina Seth
Andrew J. Lewis
Megan Galbally
Publication date
01-12-2016
Publisher
BioMed Central
Published in
BMC Pregnancy and Childbirth / Issue 1/2016
Electronic ISSN: 1471-2393
DOI
https://doi.org/10.1186/s12884-016-0915-y

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