Top

Published in:

27-02-2023 | Peri-Implant Diseases in the Maxillofacial Region | Research

Influence of keratinized mucosa on peri-implant diseases: a retrospective cohort study in humans

Authors: Caroline Argolo Brito Oliveira, Vonei Luiz Pereira, Jean Nunes dos Santos, Nara Santos Araujo, Patricia Ramos Cury

Published in: Oral and Maxillofacial Surgery | Issue 1/2024

Abstract

Objective

The present study aimed to assess the relationship between keratinized mucosa width and peri-implant diseases, namely peri-implant mucositis and peri-implantitis.

Materials and methods

Ninety-one dental implants in function for ≥ 6 months from 40 partially or completely edentulous non-smoker subjects (24 females and 16 males) were evaluated clinically and radiographically. The width of keratinized mucosa, probing depth, plaque index, bleeding on probing, and marginal bone levels were assessed. Keratinized mucosa width was categorized as ≥ 2 mm or < 2 mm.

Results

There was no statistically significant association between keratinized buccal mucosa width and peri-implant mucositis or peri-implantitis (p ≥ 0.37). In the regression analysis, peri-implantitis was associated with longer implant function time (RR: 2.55, 95% CI: 1.25–11.81, p = 0.02) and implants in the maxilla (RR: 3.15, 95% CI: 1.61–14.93, p = 0.003). Mucositis was not associated with any of the factors analyzed.

Conclusion

In conclusion, in the present sample, keratinized buccal mucosa width was not associated with peri-implant diseases, suggesting that a band of keratinized mucosa may not be necessary to maintain peri-implant health. Prospective studies are required to better understand its role in the maintenance of peri-implant health.

Caton JG, Armitage G, Berglundh et al (2018) A new classification scheme for periodontal and peri-implant diseases and conditions- Introduction and key changes from 1999 classification. J Periodontol 89(Suppl 1):S1–S8PubMed

Heitz-Mayfield LJA, Salvi GE (2018) Peri-implant mucositis. J Clin Periodontol 89(Suppl 1):S257–S266

Schwarz F, Derks J, Monje A, Wang H-L (2018) Peri-implantitis. JPeri-odontol 89(Suppl 1):S267–S290

Listgarten MA, Lang NP, Schröeder HE, Schröeder A (1991) Periodontal tissues and their counterparts around endosseous implants. Clin Oral Implants Res 2:1–19CrossRefPubMed

Lang NP, Adler R, Joss A, Nyman S (1990) Absence of bleeding on probing: An indicator of periodontal stability. J Clin Periodontol 17:714–721CrossRefPubMed

Wennström JL, Bengazi F, Lekholm U (1994) The influence of the masticatory mucosa on the peri-implant soft tissue condition. Clin Oral Implants Res 45(1):1–8CrossRef

Gobbato L, Avila-Ortiz G, Sohrabi K, Wang CW, Karimbux N (2013) The effect of keratinized mucosa width on peri-implant health: a systematic review. Int J Oral Maxillofac Implants 28(6):1536–1545CrossRefPubMed

Roccuzzo M, Grasso G, Dalmasso P (2016) Keratinized mucosa around implants in partially edentulous posterior mandible: 10-year results of a prospective comparative study. Clin Oral Implants Res 27:491–496CrossRefPubMed

Chung DM, Oh T, Shotwell JL, Misch CE, Wang HL (2006) Significance of keratinized mucosa in maintenance of dental implants with different surfaces. J Periodontol 77(8):1410–1420CrossRefPubMed

10.

Bouri A Jr, Bissada N, Al-Zahrani MS, Faddoul F, Nouneh I (2008) Width of keratinized gingiva and the health status of the supporting tissues around dental implants. Int J Oral Maxillofac Implants 23:323–326PubMed

11.

Adibrad M, Shahabuei M, Sahabi M (2009) Significance of the width of keratinized mucosa on the health status of the supporting tissue around implants supporting overdentures. J Oral Implantol XXXV:232–237CrossRef

12.

Schrott AR, Jimenez M, Hwang JW, Fiorellini J, Weber HP (2009) Five-year evaluation of the influence of keratinized mucosa on peri-implant soft-tissue health and stability around implants supporting full-arch mandibular fixed prostheses. Clin Oral Implants Res 20:1170–1177CrossRefPubMedPubMedCentral

13.

Crespi R, Capparè P, Gherlone E (2010) A 4-year evaluation of the periimplant parameters of immediately loaded implants placed in fresh extraction sockets. J Periodontol 81:1629–1634CrossRefPubMed

14.

Boynuegri D, Nemli SK, Kasko YA (2013) Significance of keratinized mucosa around dental implants: a prospective comparative study. Clin Oral Implants Res 24:928–933CrossRefPubMed

15.

Lin G, Chan H, Wang H (2013) The significance of keratinized mucosa on implant health: a systematic review. J Periodontol 84(12):1755–1767CrossRefPubMed

16.

Shimomoto T, Nakano T, Shintani A, Ono S, Inoue M, Yatani H (2021) Evaluation of the effect of keratinized mucosa on peri-implant tissue health using a multivariate analysis. J Prosthodont Res 65:198–201CrossRefPubMed

17.

Dalago HR, Schuldt Filho G, Rodrigues MA, Renvert S, Bianchini MA (2017) Risk indicators for peri-implantitis. A cross-sectional study with 916 implants. Clin Oral Implants Res 28:144–150CrossRefPubMed

18.

Frisch E, Ziebolz D, Vach K, Ratka-Krüger P (2015) The effect of keratinized mucosa width on peri-implant outcome under supportive postimplant therapy. Clin Implant Dent Relat Res 17(Suppl 1):236–244

19.

Zigdon H, Machtei EE (2008) The dimensions of keratinized mucosa around implants affect clinical and immunological parameters. Clin Oral Implants Res 19:387–392CrossRefPubMed

20.

Lim HC, Wiedemeier DB, Hämmerle CHF, Thoma DS (2019) The amount of keratinized mucosa may not influence peri-implant health in compliant patients: a retrospective 5-year analysis. J Clin Periodontol 46:354–362CrossRefPubMed

21.

Pranskunas M, Poskevicius L, Juodzbalys G, Kubilius R, Jimbo R (2016) Influence of peri-implant soft tissue condition and plaque accumulation on peri-implantitis: a systematic review. J Oral Maxillofac Res 7(3)e2:1–9

22.

Lindhe J, Lang NP (2018) Tratado de Periodontia Clínica e Implantodontia Oral, 6th edn. Guanabara Koogan, Rio de Janeiro

23.

Mombelli A, van Oosten MA, Schurch E Jr, Land NP (1987) The microbiota associated with successful or failing osseointegrated titanium implants. Oral Microbiol Immunol 2:145–151CrossRefPubMed

24.

Renvert S, Persson GR, Pirih FQ, Camargo PM (2018) Peri-implant health, peri-implant mucositis, and peri-implantitis: Case definitions and diagnostic considerations. J Periodontol 89(Suppl 1):S304–S312PubMed

25.

Hashim D, Cionca NA (2020) A comprehensive review of peri-implantitis risk factors. Curr Oral Health Rep 7:262–273CrossRef

26.

Elves LB, Coelho TDRC, de Azevedo RA, do Santos JN, Neves FS, Cury PR (2020) Systemic risk indicators for peri-implant diseases in individuals with implant-supported fixed prostheses: a cross-sectional study. Int J Oral Implantol (Berl) 13(3):255–266

27.

Ferreira SD, Silva GLM, Cortelli JR, Costa JE, Costa FO (2006) Prevalence and risk variables for peri-implant disease in Brazilian subjects. J Clin Periodontol 33:929–935CrossRefPubMed

28.

Costa FO, Takenaka-Martinez S, Cota LOM, Ferreira SD, Silva GLM, Costa JE (2012) Peri-implant disease in subjects with and without preventive maintenance: a 5-year follow-up. J Clin Periodontol 39:173–181CrossRefPubMed

29.

Ahn DH, Kim HJ, Joo JY et al (2019) Prevalence and risk factors of peri-implant mucositis and peri-implantitis after at least 7 years of loading. J Periodontal Implant Sci 49(6):397–405CrossRefPubMedPubMedCentral

30.

Konstantinidis IK, Kotsakis GA, Gerdes S, Walter MH (2015) Cross-sectional study on the prevalence and risk indicators of peri-implant diseases. Eur J Oral Implantol 8:75–88PubMed

31.

Schuldt Filho G, Dalago HR, De Souza JGO, Jovanovic S, Bianchini MA (2014) Prevalence of peri-implantitis in patients with implant-supported fixed prostheses. Quintessence Int 45(10):861–868PubMed

32.

Lee CT, Huanga YW, Zhub L, Weltman R (2017) Prevalences of peri-implantitis and peri-implant mucositis: systematic review and meta-analysis. J Dent 62:1–12CrossRefPubMed

33.

Derks J, Schaller D, Håkansson J, Wennström JL, Tomasi C, Berglundh T (2016) Peri-implantitis – onset and pattern of progression. J Clin Periodontol 43:383–388CrossRefPubMed

Title: Influence of keratinized mucosa on peri-implant diseases: a retrospective cohort study in humans
Authors: Caroline Argolo Brito Oliveira
Vonei Luiz Pereira
Jean Nunes dos Santos
Nara Santos Araujo
Patricia Ramos Cury
Publication date: 27-02-2023
Publisher: Springer Berlin Heidelberg
Keywords: Peri-Implant Diseases in the Maxillofacial Region
Prosthesis
Bleeding on Probing
Dental Plaque Index
Published in: Oral and Maxillofacial Surgery / Issue 1/2024
Print ISSN: 1865-1550
Electronic ISSN: 1865-1569
DOI: https://doi.org/10.1007/s10006-023-01144-8

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Influence of keratinized mucosa on peri-implant diseases: a retrospective cohort study in humans

Abstract

Objective

Materials and methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objective

Materials and methods

Results

Conclusion

Please log in to get access to this content

Other articles of this Issue 1/2024

Does watching an informative video reduce the anxiety in patients undergoing third molar surgery: a systematic review of randomized controlled trials

Correction to: Esthetic restoration of progressive hemifacial atrophy (Parry‑Romberg disease) by free fat grafting using computerized‑assisted mapping

Comparison of swallowing disorder in patients with tongue cancer undergoing reconstruction with either a radial forearm free flap or a submental island flap

Use of ozone therapy in Implant Dentistry: a systematic review

3-dimensional analysis of nasal soft tissue alterations following maxillary Lefort I advancement with and without impaction using 3D photogrammetry scanner

Did physical aggression in women increase during the novel coronavirus 2019 (COVID-19) pandemic? A perspective of facial trauma