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Open Access 04-09-2023 | Translational Research

Performance of a Nonlinear Magnetic Handheld Probe for Intraoperative Sentinel Lymph Node Detection: A Phantom Study

Authors: Eliane R. Nieuwenhuis, PhD, Nida Mir, MSc, Melissa M. Horstman-van de Loosdrecht, PhD, Antoi P. W. Meeuwis, Maarten G. J. de Bakker, MSc, Tom W. J. Scheenen, PhD, Lejla Alic, PhD

Published in: Annals of Surgical Oncology | Issue 13/2023

Abstract

Objective

This study investigates the performance of the DiffMag handheld probe (nonlinear magnetometry), to be used for sentinel lymph node detection. Furthermore, the performance of DiffMag is compared with a gamma probe and a first-order magnetometer (Sentimag^®, linear magnetometry).

Methods

The performance of all three probes was evaluated based on longitudinal distance, transverse distance, and resolving power for two tracer volumes. A phantom was developed to investigate the performance of the probes for a clinically relevant situation in the floor of the mouth (FOM).

Results

Considering the longitudinal distance, both DiffMag handheld and Sentimag^® probe had comparable performance, while the gamma probe was able to detect at least a factor of 10 deeper. Transverse distances of 13, 11, and 51 mm were measured for the small tracer volume by the DiffMag handheld, Sentimag^®, and the gamma probe, respectively. For the large tracer volume this was 21, 18, and 55 mm, respectively. The full width at half maximum, at 7 mm probe height from the phantom surface, was 14, 12, and 18 mm for the small tracer volume and 15, 18, and 25 mm for the large tracer volume with the DiffMag handheld, Sentimag^®, and gamma probe, respectively.

Conclusions

With a high resolving power but limited longitudinal distance, the DiffMag handheld probe seems suitable for detecting SLNs which are in close proximity to the primary tumor. In this study, comparable results were shown using linear magnetometry. The gamma probe reached 10 times deeper, but has a lower resolving power compared with the DiffMag handheld probe.

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Title: Performance of a Nonlinear Magnetic Handheld Probe for Intraoperative Sentinel Lymph Node Detection: A Phantom Study
Authors: Eliane R. Nieuwenhuis, PhD
Nida Mir, MSc
Melissa M. Horstman-van de Loosdrecht, PhD
Antoi P. W. Meeuwis
Maarten G. J. de Bakker, MSc
Tom W. J. Scheenen, PhD
Lejla Alic, PhD
Publication date: 04-09-2023
Publisher: Springer International Publishing
Published in: Annals of Surgical Oncology / Issue 13/2023
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI: https://doi.org/10.1245/s10434-023-14166-z

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Performance of a Nonlinear Magnetic Handheld Probe for Intraoperative Sentinel Lymph Node Detection: A Phantom Study

Abstract

Objective

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objective

Methods

Results

Conclusions

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