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Published in: CardioVascular and Interventional Radiology 5/2011

01-10-2011 | Clinical Investigation

Percutaneous Treatment of Biliary Cast Syndrome After Orthotopic Liver Transplantation: Comparison of Mechanical Versus Hydraulic Rheolytic Cast Extraction

Authors: R. López-Benítez, M. O. Wielpütz, M. G. H. Bryant, Tom Ganten, G. M. Richter, N. Flach, P. J. Hallscheidt

Published in: CardioVascular and Interventional Radiology | Issue 5/2011

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Abstract

Purpose

Biliary cast syndrome (BCS) is the presence of casts within the intrahepatic or extrahepatic biliary system after orthotopic liver transplantation. Our work compares two percutaneous methods for BCS treatment: the mechanical cast-extraction technique (MCE) versus the hydraulic cast-extraction (HCE) technique using a rheolytic system.

Materials and Methods

A total of 24 patients were included in the study. Six patients were referred for HCE, and 18 patients were treated with MCE. A statistically significant larger number of sessions was required in the MCE group (21.0, range 11 to 72 sessions) (p = 0.033).

Results

Median therapy duration was shorter in the HCE group at 2.4 months (range 2 to 5) compared with 6.7 months (range 3 to 39) in the MCE group (p < 0.001). Both patient acceptance was better and costs for total therapy were 40% less in the HCE group. No significant differences where found concerning clinical and biochemical improvement or graft and patient survival.

Conclusion

The use of the hydraulic rheolytic system decreased total therapy time, thereby decreasing the induced inflammation time of the biliary tree. A significant benefit of HCE has been observed in our patients when we compare our results with those of MCE.
Literature
1.
go back to reference Starzl TE, Putnam CW, Hansbrough JF, Porter KA, Reid HA (1997) Biliary complications after liver transplantation: With special reference to the biliary cast syndrome and techniques of secondary duct repair. Surgery 81:212–221 Starzl TE, Putnam CW, Hansbrough JF, Porter KA, Reid HA (1997) Biliary complications after liver transplantation: With special reference to the biliary cast syndrome and techniques of secondary duct repair. Surgery 81:212–221
2.
go back to reference Waldram R, Williams R, Calne RY (1975) Bile composition and bile cast formation after transplantation of the liver in man. Transplantation 19:382–387PubMedCrossRef Waldram R, Williams R, Calne RY (1975) Bile composition and bile cast formation after transplantation of the liver in man. Transplantation 19:382–387PubMedCrossRef
3.
go back to reference Shah JN, Haigh WG, Lee SP et al (2003) Biliary casts after orthotopic liver transplantation: Clinical factors, treatment, biochemical analysis. Am J Gastroenterol 98:1861–1867PubMedCrossRef Shah JN, Haigh WG, Lee SP et al (2003) Biliary casts after orthotopic liver transplantation: Clinical factors, treatment, biochemical analysis. Am J Gastroenterol 98:1861–1867PubMedCrossRef
4.
go back to reference Gor NV, Levy RM, Ahn J, Kogan D, Dodson SF, Cohen SM (2008) Biliary cast syndrome following liver transplantation: Predictive factors and clinical outcomes. Liver Transpl 14:1466–1472PubMedCrossRef Gor NV, Levy RM, Ahn J, Kogan D, Dodson SF, Cohen SM (2008) Biliary cast syndrome following liver transplantation: Predictive factors and clinical outcomes. Liver Transpl 14:1466–1472PubMedCrossRef
5.
go back to reference Barton P, Maier A, Steininger R, Muhlbacher F, Lechner G (1995) Biliary sludge after liver transplantation: 1. Imaging findings and efficacy of various imaging procedures. AJR Am J Roentgenol 164:859–864PubMed Barton P, Maier A, Steininger R, Muhlbacher F, Lechner G (1995) Biliary sludge after liver transplantation: 1. Imaging findings and efficacy of various imaging procedures. AJR Am J Roentgenol 164:859–864PubMed
6.
go back to reference Khuroo MS, Al Ashgar H, Khuroo NS et al (2005) Biliary disease after liver transplantation: the experience of the King Faisal Specialist Hospital and Research Center, Riyadh. J Gastroenterol Hepatol 20:217–228PubMedCrossRef Khuroo MS, Al Ashgar H, Khuroo NS et al (2005) Biliary disease after liver transplantation: the experience of the King Faisal Specialist Hospital and Research Center, Riyadh. J Gastroenterol Hepatol 20:217–228PubMedCrossRef
7.
go back to reference Sheng R, Ramirez CB, Zajko AB, Campbell WL (1996) Biliary stones and sludge in liver transplant patients: a 13-year experience. Radiology 198:243–247PubMed Sheng R, Ramirez CB, Zajko AB, Campbell WL (1996) Biliary stones and sludge in liver transplant patients: a 13-year experience. Radiology 198:243–247PubMed
8.
go back to reference Baron TH, Yates RM 3rd, Morgan DE, Eckhoff DE, Bynon JS (2000) Biliary cast syndrome: successful endoscopic treatment. Gastrointest Endosc 52:78–79PubMedCrossRef Baron TH, Yates RM 3rd, Morgan DE, Eckhoff DE, Bynon JS (2000) Biliary cast syndrome: successful endoscopic treatment. Gastrointest Endosc 52:78–79PubMedCrossRef
9.
go back to reference Katsinelos P, Kountouras J, Chatzimavroudis G, Zavos C, Pilpilidis I, Paroutoglou G (2008) Combined endoscopic and ursodeoxycholic acid treatment of biliary cast syndrome in a non-transplant patient. World J Gastroenterol 14:5223–5225PubMedCrossRef Katsinelos P, Kountouras J, Chatzimavroudis G, Zavos C, Pilpilidis I, Paroutoglou G (2008) Combined endoscopic and ursodeoxycholic acid treatment of biliary cast syndrome in a non-transplant patient. World J Gastroenterol 14:5223–5225PubMedCrossRef
10.
go back to reference Loehr SP, Hamilton C, Gargan K, Gilliam J (2002) Use of the Angiojet thrombectomy device to facilitate removal of impacted intrahepatic ductal debris. AJR Am J Roentgenol 179:370–372PubMed Loehr SP, Hamilton C, Gargan K, Gilliam J (2002) Use of the Angiojet thrombectomy device to facilitate removal of impacted intrahepatic ductal debris. AJR Am J Roentgenol 179:370–372PubMed
11.
go back to reference Yang Y, Li H, Fu BS et al (2008) Hepatic artery complications after orthotopic liver transplantation: interventional treatment or retransplantation? Chin Med J (Engl) 121:1997–2000 Yang Y, Li H, Fu BS et al (2008) Hepatic artery complications after orthotopic liver transplantation: interventional treatment or retransplantation? Chin Med J (Engl) 121:1997–2000
12.
go back to reference Margheri M, Vittori G, Vecchio S et al (2008) Early and long-term clinical results of AngioJet rheolytic thrombectomy in patients with acute pulmonary embolism. Am J Cardiol 101:252–258PubMedCrossRef Margheri M, Vittori G, Vecchio S et al (2008) Early and long-term clinical results of AngioJet rheolytic thrombectomy in patients with acute pulmonary embolism. Am J Cardiol 101:252–258PubMedCrossRef
13.
go back to reference Kakkos SK, Andrzejewski T, Haddad JA, et al. (2007) Equivalent secondary patency rates of upper extremity Vectra Vascular Access Grafts and transposed brachial-basilic fistulas with aggressive access surveillance and endovascular treatment. J Vasc Surg 47(2):407–414PubMedCrossRef Kakkos SK, Andrzejewski T, Haddad JA, et al. (2007) Equivalent secondary patency rates of upper extremity Vectra Vascular Access Grafts and transposed brachial-basilic fistulas with aggressive access surveillance and endovascular treatment. J Vasc Surg 47(2):407–414PubMedCrossRef
14.
go back to reference Barbato JE, Wholey MH (2007) Use of AngioJet mechanical thrombectomy for acute peripheral ischemia associated with stent fracture. Catheter Cardiovasc Interv 70:795–798PubMedCrossRef Barbato JE, Wholey MH (2007) Use of AngioJet mechanical thrombectomy for acute peripheral ischemia associated with stent fracture. Catheter Cardiovasc Interv 70:795–798PubMedCrossRef
15.
go back to reference Siablis D, Liatsikos EN, Goumenos D et al (2005) Percutaneous rheolytic thrombectomy for treatment of acute renal-artery thrombosis. J Endourol 19:68–71PubMedCrossRef Siablis D, Liatsikos EN, Goumenos D et al (2005) Percutaneous rheolytic thrombectomy for treatment of acute renal-artery thrombosis. J Endourol 19:68–71PubMedCrossRef
16.
go back to reference Lin PH, Zhou W, Dardik A et al (2006) Catheter-direct thrombolysis versus pharmacomechanical thrombectomy for treatment of symptomatic lower extremity deep venous thrombosis. Am J Surg 192:782–788PubMedCrossRef Lin PH, Zhou W, Dardik A et al (2006) Catheter-direct thrombolysis versus pharmacomechanical thrombectomy for treatment of symptomatic lower extremity deep venous thrombosis. Am J Surg 192:782–788PubMedCrossRef
17.
go back to reference Rigatelli G, Cardaioli P, Roncon L, Giordan M, Milan T, Zonzin P (2006) Combined percutaneous aspiration thrombectomy and rheolytic thrombectomy in massive subacute vena cava thrombosis with IVC filter occlusion. J Endovasc Ther 13:373–376PubMedCrossRef Rigatelli G, Cardaioli P, Roncon L, Giordan M, Milan T, Zonzin P (2006) Combined percutaneous aspiration thrombectomy and rheolytic thrombectomy in massive subacute vena cava thrombosis with IVC filter occlusion. J Endovasc Ther 13:373–376PubMedCrossRef
18.
go back to reference Arko FR, Davis CM 3rd, Murphy EH et al (2007) Aggressive percutaneous mechanical thrombectomy of deep venous thrombosis: early clinical results. Arch Surg 142:513–519PubMedCrossRef Arko FR, Davis CM 3rd, Murphy EH et al (2007) Aggressive percutaneous mechanical thrombectomy of deep venous thrombosis: early clinical results. Arch Surg 142:513–519PubMedCrossRef
19.
go back to reference Kawamura A, Tilem M, Gossman DE (2006) Rheolytic thrombectomy for thromboembolic occlusion of the internal carotid artery complicating coronary intervention. J Invasive Cardiol 18:E108–E110PubMed Kawamura A, Tilem M, Gossman DE (2006) Rheolytic thrombectomy for thromboembolic occlusion of the internal carotid artery complicating coronary intervention. J Invasive Cardiol 18:E108–E110PubMed
20.
go back to reference Mayer TE, Hamann GF, Schulte-Altedorneburg G, Bruckmann H (2005) Treatment of vertebrobasilar occlusion by using a coronary waterjet thrombectomy device: a pilot study. AJNR Am J Neuroradiol 26:1389–1394PubMed Mayer TE, Hamann GF, Schulte-Altedorneburg G, Bruckmann H (2005) Treatment of vertebrobasilar occlusion by using a coronary waterjet thrombectomy device: a pilot study. AJNR Am J Neuroradiol 26:1389–1394PubMed
21.
go back to reference De Rosa S, Cirillo P, De Luca G et al (2007) Rheolytic thrombectomy during percutaneous coronary intervention improves long-term outcome in high-risk patients with acute myocardial infarction. J Interv Cardiol 20:292–298PubMedCrossRef De Rosa S, Cirillo P, De Luca G et al (2007) Rheolytic thrombectomy during percutaneous coronary intervention improves long-term outcome in high-risk patients with acute myocardial infarction. J Interv Cardiol 20:292–298PubMedCrossRef
22.
go back to reference Dudar BM, Kim HE (2007) Massive air embolus treated with rheolytic thrombectomy. J Invasive Cardiol 19:E182–E184PubMed Dudar BM, Kim HE (2007) Massive air embolus treated with rheolytic thrombectomy. J Invasive Cardiol 19:E182–E184PubMed
Metadata
Title
Percutaneous Treatment of Biliary Cast Syndrome After Orthotopic Liver Transplantation: Comparison of Mechanical Versus Hydraulic Rheolytic Cast Extraction
Authors
R. López-Benítez
M. O. Wielpütz
M. G. H. Bryant
Tom Ganten
G. M. Richter
N. Flach
P. J. Hallscheidt
Publication date
01-10-2011
Publisher
Springer-Verlag
Published in
CardioVascular and Interventional Radiology / Issue 5/2011
Print ISSN: 0174-1551
Electronic ISSN: 1432-086X
DOI
https://doi.org/10.1007/s00270-010-9998-4

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