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Published in: Insights into Imaging 5/2013

Open Access 01-10-2013 | Pictorial Review

Pelvic heterotopic ossification: when CT comes to the aid of MR imaging

Authors: Andrea Zagarella, Elisabetta Impellizzeri, Roberta Maiolino, Raffaele Attolini, Maria Chiara Castoldi

Published in: Insights into Imaging | Issue 5/2013

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Abstract

Objective

This article compares various imaging aspects of magnetic resonance (MR) and computed tomography (CT) of heterotopic ossification (HO) in the pelvic soft tissues in paraplegic patients. Our aim is to highlight the benefits of integrating MR and CT imaging in the diagnosis of immature HO, which may be challenging with MR images alone.

Methods

Paraplegic patients examined on the same day by contrast-enhanced 0.4-T pelvic MR and unenhanced CT for pressure-sore-related infections were selected. MR imaging was performed on a Hitachi-Aperto 0.4 T; the Open Magnet served as a more favourable configuration for the required limb positioning of these patients. CT images were attained on a six-slice Siemens-Somaton-Emotion.

Results

MR images of HO differ according to the degree of bone maturity. The more immature the HO process, the more heterogeneous is the signal, characterised mostly by focal iso-hypointensity on T1-weighted images and hyperintensity on T2-weighted/short TI inversion recovery (STIR). These characteristics correlate to different CT patterns.

Conclusions

MR and CT features of pelvic HO in paralysed patients were reviewed with a focus on the different aspects associated with the degree of ossification. Based solely on the MR findings, immature heterotopic ossification may be difficult to differentiate from other soft tissue pelvic lesions.

Teaching points

• The pelvis and hip are common locations of heterotopic ossifications (HO), often occurring in paraplegic patients.
• With respect to HO, MR imaging allows for a confident diagnosis in mature ossified lesions only. The MR aspect of immature ossification may be confused with other pathologies.
• Plain radiographs and CT may show various phases of ossification: amorphous calcification, immature and mature ossification.
• Integrating MR with CT can help recognise HO foci and differentiate them from infections and other soft tissue lesions.
Literature
1.
go back to reference Seipel R, Langner S, Platz T et al (2011) Neurogenic heterotopic ossification:epidemiology and morphology on conventional radiographs in an early neurological rehabilitation population. Skelet Radiol 28:151–160 Seipel R, Langner S, Platz T et al (2011) Neurogenic heterotopic ossification:epidemiology and morphology on conventional radiographs in an early neurological rehabilitation population. Skelet Radiol 28:151–160
2.
go back to reference Ledermann HP, Schweitzer ME, Morrison WB et al (2002) Pelvic heterotopic ossification: MR imaging characteristics. Radiology 222:189–195PubMedCrossRef Ledermann HP, Schweitzer ME, Morrison WB et al (2002) Pelvic heterotopic ossification: MR imaging characteristics. Radiology 222:189–195PubMedCrossRef
3.
go back to reference Wick L, Berger M, Knecht H et al (2005) Magnetic resonance signal alterations in the acute onset of heterotopic ossification in patients with spinal cord injury. Eur Radiol 15:1867–1875PubMedCrossRef Wick L, Berger M, Knecht H et al (2005) Magnetic resonance signal alterations in the acute onset of heterotopic ossification in patients with spinal cord injury. Eur Radiol 15:1867–1875PubMedCrossRef
4.
go back to reference Mc Carthy EF, Sundaram M (2005) Heterotopic ossification: a review. Skelet Radiol 34:609–619CrossRef Mc Carthy EF, Sundaram M (2005) Heterotopic ossification: a review. Skelet Radiol 34:609–619CrossRef
5.
go back to reference Wharton GW, Morgan TH (1975) Heteropic ossification. J Bone Joint Surg Am 52:105–112 Wharton GW, Morgan TH (1975) Heteropic ossification. J Bone Joint Surg Am 52:105–112
6.
go back to reference Freed JH, Hahn H, Menter R et al (1982) The use of the three-phase bone scan in the early diagnosis of heterotopic ossification (HO) and in the evaluation of Didronel therapy. Paraplegia 20:208–216PubMedCrossRef Freed JH, Hahn H, Menter R et al (1982) The use of the three-phase bone scan in the early diagnosis of heterotopic ossification (HO) and in the evaluation of Didronel therapy. Paraplegia 20:208–216PubMedCrossRef
7.
go back to reference Bressler EL, Marn CS, Gore RM et al (1987) Evaluation of ectopic bone by CT. Am J Roentgenol 148:931–935CrossRef Bressler EL, Marn CS, Gore RM et al (1987) Evaluation of ectopic bone by CT. Am J Roentgenol 148:931–935CrossRef
8.
go back to reference Kransdorf MJ, Meis JM, Jeilinek JS (1991) Myositis ossificans:MR appearance with radiologic-pathologic correlation. AJR Am J Roentgenol 157:1243–1248PubMedCrossRef Kransdorf MJ, Meis JM, Jeilinek JS (1991) Myositis ossificans:MR appearance with radiologic-pathologic correlation. AJR Am J Roentgenol 157:1243–1248PubMedCrossRef
9.
go back to reference De Smet AA, Norris MA, Fisher DR et al (1992) Magnetic resonance imaging of myositis ossificans: analysis of seven cases. Skelet Radiol 21:503–507CrossRef De Smet AA, Norris MA, Fisher DR et al (1992) Magnetic resonance imaging of myositis ossificans: analysis of seven cases. Skelet Radiol 21:503–507CrossRef
10.
go back to reference Shirkhoda A, Armin AR, Bis KG et al (1995) MR imaging of myositis ossificans: variable patterns at different stages. J Magn Reson Imaging 5:287–292PubMedCrossRef Shirkhoda A, Armin AR, Bis KG et al (1995) MR imaging of myositis ossificans: variable patterns at different stages. J Magn Reson Imaging 5:287–292PubMedCrossRef
11.
go back to reference Rossier AB, Bussat P, Infante F et al (1973) Current fact of para-osteo-arthropathy POA. Paraplegia 11:38–78PubMedCrossRef Rossier AB, Bussat P, Infante F et al (1973) Current fact of para-osteo-arthropathy POA. Paraplegia 11:38–78PubMedCrossRef
12.
go back to reference Huang AB, Schweitzer ME, Hume E et al (1998) Osteomyelitis of the pelvis/hips in paralyzed patients: accuracy and clinical utility of MRI. J Comput Assist Tomogr 22:437–443PubMedCrossRef Huang AB, Schweitzer ME, Hume E et al (1998) Osteomyelitis of the pelvis/hips in paralyzed patients: accuracy and clinical utility of MRI. J Comput Assist Tomogr 22:437–443PubMedCrossRef
13.
go back to reference Subhawong TK, Fishman E, Swart J et al (2010) Soft-tissue masses and masslike conditions: what does CT add to diagnosis and management? AJR Am J Roentgenol 194:1559–1567PubMedPubMedCentralCrossRef Subhawong TK, Fishman E, Swart J et al (2010) Soft-tissue masses and masslike conditions: what does CT add to diagnosis and management? AJR Am J Roentgenol 194:1559–1567PubMedPubMedCentralCrossRef
14.
go back to reference Turecki MB, Taljanovic MS, Stubbs AY et al (2010) Imaging of musculoskeletal soft tissue infections. Skelet Radiol 39:957–971CrossRef Turecki MB, Taljanovic MS, Stubbs AY et al (2010) Imaging of musculoskeletal soft tissue infections. Skelet Radiol 39:957–971CrossRef
15.
go back to reference Thomas BJ, Amstutz HC (1987) Prevention of heterotopic bone formation: clinical experience with diphosphonates. Hip 1987:59–69 Thomas BJ, Amstutz HC (1987) Prevention of heterotopic bone formation: clinical experience with diphosphonates. Hip 1987:59–69
16.
go back to reference Wharton GW, Morgan TH (1970) Ankylosis in the paralyzed patient. J Bone Joint Surg Am 52:105–112PubMed Wharton GW, Morgan TH (1970) Ankylosis in the paralyzed patient. J Bone Joint Surg Am 52:105–112PubMed
Metadata
Title
Pelvic heterotopic ossification: when CT comes to the aid of MR imaging
Authors
Andrea Zagarella
Elisabetta Impellizzeri
Roberta Maiolino
Raffaele Attolini
Maria Chiara Castoldi
Publication date
01-10-2013
Publisher
Springer Berlin Heidelberg
Published in
Insights into Imaging / Issue 5/2013
Electronic ISSN: 1869-4101
DOI
https://doi.org/10.1007/s13244-013-0265-5

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