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Published in: Supportive Care in Cancer 4/2013

01-04-2013 | Original Article

Pattern and characteristics of advanced cancer patients admitted to hospices in Italy

Authors: Sebastiano Mercadante, Alessandro Valle, Silvana Sabba, Antonio Orlando, Francesca Guolo, Loretta Gulmini, Sara Ori, Rosanna Bellingardo, Alessandra Casuccio

Published in: Supportive Care in Cancer | Issue 4/2013

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Abstract

The aim of this multicenter study was to assess the pattern and the characteristics of advanced cancer patients admitted to hospices. A consecutive sample of patients admitted in a period of 6 months was taken into consideration. Two hundred thirty-six patients admitted to hospices were consecutively assessed. Ninety-six percent of patients were admitted in acute hospital in the previous 3 months, with a mean time spent in hospital of 34.5 days, and 47 % of patients had received chemotherapy the month before hospice admission. Thirty-four percent of patients for whom data were available had significant persistent pain, and 44 % of them presented episodes of breakthrough pain. Sixty-one percent of patients were receiving opioid drugs at admission, and 70 % the day before death, with parenteral morphine and transdermal fentanyl being the opioids most frequently administered. The mean admission time in hospice was 18.4 days. Eighty-six percent died in hospice. Palliative sedation was performed in 25 % of patients who died in hospice. The short survival and the number of patients dying in hospice were the principal finding, as it appears that hospice admission is only one way for end of life treatments. Patients receive specialized palliative care only for 2–3 weeks before death, implying an inacceptable timing for patients with several problems presumed to be present early during the course of disease. Data from hospice activities in Italy strongly suggest to spread palliative care in other settings, other than home care and hospice, to intercept oncologic patients in their disease trajectory early.
Literature
1.
go back to reference Sbanotto A, Burnhill R (1998) Palliative care in Italy: the current situation. Support Care Cancer 6:426–429PubMedCrossRef Sbanotto A, Burnhill R (1998) Palliative care in Italy: the current situation. Support Care Cancer 6:426–429PubMedCrossRef
2.
go back to reference Zucco F (2007) Hospice in Italia, Ministero della Salute Zucco F (2007) Hospice in Italia, Ministero della Salute
3.
go back to reference Mercadante S, Villari P, Ferrera P (2003) A model of acute symptom control unit: pain relief and palliative care unit of la Maddalena cancer center. Support Care Cancer 11:114–119PubMed Mercadante S, Villari P, Ferrera P (2003) A model of acute symptom control unit: pain relief and palliative care unit of la Maddalena cancer center. Support Care Cancer 11:114–119PubMed
4.
go back to reference Mercadante S, Intravaia G, Villari P, Ferrera P, David F, Casuccio A et al (2008) Clinical and financial analysis of an acute palliative care unit in an oncological department. Palliat Med 22:760–767PubMedCrossRef Mercadante S, Intravaia G, Villari P, Ferrera P, David F, Casuccio A et al (2008) Clinical and financial analysis of an acute palliative care unit in an oncological department. Palliat Med 22:760–767PubMedCrossRef
5.
go back to reference Mercadante S, Vitrano V (2010) Palliative care in Italy: problems area. Minerva Anestesiol 76:1060–1071PubMed Mercadante S, Vitrano V (2010) Palliative care in Italy: problems area. Minerva Anestesiol 76:1060–1071PubMed
6.
go back to reference Costantini M, Toscani F, Gallucci M, Brunelli C, Miccinesi G, Tamburini M et al (1999) Terminal cancer patients and timing of referral to palliative care: a multicenter prospective cohort study. J Pain Symptom Manage 18:243–252PubMedCrossRef Costantini M, Toscani F, Gallucci M, Brunelli C, Miccinesi G, Tamburini M et al (1999) Terminal cancer patients and timing of referral to palliative care: a multicenter prospective cohort study. J Pain Symptom Manage 18:243–252PubMedCrossRef
7.
go back to reference Peruselli C, Di Giulio P, Toscani F, Gallucci M, Brunelli C, Costantini M et al (1999) Home palliative care for terminal cancer patients: a survey on the final week of life. Palliat Med 13:233–241PubMedCrossRef Peruselli C, Di Giulio P, Toscani F, Gallucci M, Brunelli C, Costantini M et al (1999) Home palliative care for terminal cancer patients: a survey on the final week of life. Palliat Med 13:233–241PubMedCrossRef
8.
go back to reference Mercadante S, Valle A, Porzio G, Costanzo BV, Fusco F, Aielli F, Adile C, Fara B, Casuccio A (2011) How do cancer patients receiving palliative care at home die? a descriptive study. J Pain Symptom Manage 42:702–709PubMedCrossRef Mercadante S, Valle A, Porzio G, Costanzo BV, Fusco F, Aielli F, Adile C, Fara B, Casuccio A (2011) How do cancer patients receiving palliative care at home die? a descriptive study. J Pain Symptom Manage 42:702–709PubMedCrossRef
9.
go back to reference Cheng WW, Willey J, Palmer JL, Zhang T, Bruera E (2005) Interval between palliative care referral and death among patients treated at a comprehensive cancer center. J Palliat Med 8:1025–1032PubMedCrossRef Cheng WW, Willey J, Palmer JL, Zhang T, Bruera E (2005) Interval between palliative care referral and death among patients treated at a comprehensive cancer center. J Palliat Med 8:1025–1032PubMedCrossRef
10.
go back to reference Costantini M, Beccaro M, Merlo F (2005) The last three months of life of Italian cancer patients. Methods, sample characteristics and response rate of he Italian Survey of the Dying of cancer (ISDOC). Palliat Med 19:628–638PubMedCrossRef Costantini M, Beccaro M, Merlo F (2005) The last three months of life of Italian cancer patients. Methods, sample characteristics and response rate of he Italian Survey of the Dying of cancer (ISDOC). Palliat Med 19:628–638PubMedCrossRef
12.
go back to reference Temel J, Greer J, Muzikansky A et al (2010) Early palliative care for patients with metastatic non-small-cell lung cancer. N Eng J Med 363:733–742CrossRef Temel J, Greer J, Muzikansky A et al (2010) Early palliative care for patients with metastatic non-small-cell lung cancer. N Eng J Med 363:733–742CrossRef
13.
go back to reference Saito AM, Landrum MB, Neville BA, Ayanian JZ, Earle C (2011) The effect on survival of continuing chemotherapy to near death. BMC Palliat Care 10:14PubMedCrossRef Saito AM, Landrum MB, Neville BA, Ayanian JZ, Earle C (2011) The effect on survival of continuing chemotherapy to near death. BMC Palliat Care 10:14PubMedCrossRef
14.
go back to reference Mercadante S, Ferrera P, Casuccio A (2010) The use of opioids in the last week of life in an acute palliative care unit. Am J Hosp Palliat Care 27:514–517PubMedCrossRef Mercadante S, Ferrera P, Casuccio A (2010) The use of opioids in the last week of life in an acute palliative care unit. Am J Hosp Palliat Care 27:514–517PubMedCrossRef
15.
go back to reference Mercadante S, Villari P, Casuccio A (2011) An Italian survey on the attitudes in treating breakthrough cancer pain in hospice. Support Care Cancer 19:979–983PubMedCrossRef Mercadante S, Villari P, Casuccio A (2011) An Italian survey on the attitudes in treating breakthrough cancer pain in hospice. Support Care Cancer 19:979–983PubMedCrossRef
16.
go back to reference Mercadante S, Porzio G, Valle A, Fusco F, Aielli F, Costanzo V (2011) Palliative sedation in patients with advanced cancer followed at home: a systematic review. J Pain Symptom Manage 41:754–760PubMedCrossRef Mercadante S, Porzio G, Valle A, Fusco F, Aielli F, Costanzo V (2011) Palliative sedation in patients with advanced cancer followed at home: a systematic review. J Pain Symptom Manage 41:754–760PubMedCrossRef
17.
go back to reference Mercadante S, Intravaia G, Villari P, Ferrera P, David F, Casuccio A (2009) Controlled sedation for refractory symptoms in dying patients. J Pain Symptom Manage 37:771–779PubMedCrossRef Mercadante S, Intravaia G, Villari P, Ferrera P, David F, Casuccio A (2009) Controlled sedation for refractory symptoms in dying patients. J Pain Symptom Manage 37:771–779PubMedCrossRef
18.
go back to reference Bruera E, Hui D (2011) Palliative care units: the best option for the most distressed. Arch Intern Med 171:1601PubMedCrossRef Bruera E, Hui D (2011) Palliative care units: the best option for the most distressed. Arch Intern Med 171:1601PubMedCrossRef
Metadata
Title
Pattern and characteristics of advanced cancer patients admitted to hospices in Italy
Authors
Sebastiano Mercadante
Alessandro Valle
Silvana Sabba
Antonio Orlando
Francesca Guolo
Loretta Gulmini
Sara Ori
Rosanna Bellingardo
Alessandra Casuccio
Publication date
01-04-2013
Publisher
Springer-Verlag
Published in
Supportive Care in Cancer / Issue 4/2013
Print ISSN: 0941-4355
Electronic ISSN: 1433-7339
DOI
https://doi.org/10.1007/s00520-012-1608-3

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