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Health and Quality of Life Outcomes
Published in: Health and Quality of Life Outcomes 1/2016

Open Access 01-12-2016 | Review

Patient-reported outcome measures in patients with peripheral arterial disease: a systematic review of psychometric properties

Authors: Edith Poku, Rosie Duncan, Anju Keetharuth, Munira Essat, Patrick Phillips, Helen Buckley Woods, Simon Palfreyman, Georgina Jones, Eva Kaltenthaler, Jonathan Michaels

Published in: Health and Quality of Life Outcomes | Issue 1/2016

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Abstract

Background

Peripheral arterial disease (PAD) is generally associated with considerable morbidity and reduced quality of life. Patient-reported outcome measures (PROMs) provide important information about the burden of disease and impact of treatment in affected patients.

Objectives

The objective of the review was to identify and appraise studies reporting the psychometric evaluation of PROMs administered to a specified population of patients with PAD with a view to recommending suitable PROMs.

Methods

A systematic review of peer-reviewed English language articles was undertaken to identify primary studies reporting psychometric properties of PROMs in English-speaking patients with various stages of PAD. Comprehensive searches were completed up until January 2015. Study selection, data extraction and quality assessment were undertaken independently by at least two researchers. Findings were presented as tabular and narrative summaries based on accepted guidance.

Results

Psychometric evaluation of 6 generic and 7 condition-specific PROMs reported in 14 studies contributed data to the review. The frequently reported measure was the SF-36 (n = 11 studies); others included the Walking Impairment Questionnaire (n = 8 studies), EQ-5D (n = 5 studies) and the Vascular Quality of Life Questionnaire (n = 3 studies). Studies included a diverse PAD population and varied in methodology, including approach to validation of PROMs.

Conclusions

Various PROMs have been validated in patients with PAD but no study provided evidence of a full psychometric evaluation in the patient population. Careful selection is required to identify reliable and valid PROMs to use in clinical and research settings.
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Metadata
Title
Patient-reported outcome measures in patients with peripheral arterial disease: a systematic review of psychometric properties
Authors
Edith Poku
Rosie Duncan
Anju Keetharuth
Munira Essat
Patrick Phillips
Helen Buckley Woods
Simon Palfreyman
Georgina Jones
Eva Kaltenthaler
Jonathan Michaels
Publication date
01-12-2016
Publisher
BioMed Central
Published in
Health and Quality of Life Outcomes / Issue 1/2016
Electronic ISSN: 1477-7525
DOI
https://doi.org/10.1186/s12955-016-0563-y

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