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Published in: BMC Public Health 1/2013

Open Access 01-12-2013 | Research article

Patient and health system delay among patients with pulmonary tuberculosis in Beira city, Mozambique

Authors: Abuchahama Saifodine, Paula Samo Gudo, Mohsin Sidat, James Black

Published in: BMC Public Health | Issue 1/2013

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Abstract

Background

TB control is based on the rapid identification of cases and their effective treatment. However, many studies have shown that there are important delays in diagnosis and treatment of patients with TB. The purpose of this study was to assess the prevalence of and identify risk factors associated with patient delay and health system delay among newly diagnosed patients with pulmonary TB.

Methods

A cross sectional study was carried out in Beira city, Mozambique between September 2009 and February 2010. Patients in the first month of treatment were consecutively selected to this study if they had a diagnosis of pulmonary TB, had no history of previous TB treatment, and were 18 years or older and provided informed consent. Data was obtained through a questionnaire administered to the patients and from patients’ files.

Results

Among the 622 patients included in the study the median age was 32 years (interquartile range, 26–40) and 272 (43.7%) were females. The median total delay, patient delay and health system delay was 150 days (interquartile range, 91–240), 61 days (28–113) and 62 days (37–120), respectively. The contribution of patient delay and health system delay to total delay was similar. Farming, visiting first a traditional healer, low TB knowledge and coexistence of a chronic disease were associated with increased patient delay. More than two visits to a health facility, farming and coexistence of a chronic disease were associated with increased health system delay.

Conclusions

This study revealed a long total delay with a similar contribution of patient delay and health system delay. To reduce the total delay in this setting we need a combination of interventions to encourage patients to seek appropriate health care earlier and to expedite TB diagnosis within the health care system.
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Literature
2.
go back to reference Ward J, Siskind V, Konstantinos A: Patient and health care system delays in Queensland tuberculosis patients, 1985–1998. Int J Tuberc Lung Dis. 2001, 5: 1021-1027.PubMed Ward J, Siskind V, Konstantinos A: Patient and health care system delays in Queensland tuberculosis patients, 1985–1998. Int J Tuberc Lung Dis. 2001, 5: 1021-1027.PubMed
3.
go back to reference Gagliotti C, Resi D, Moro ML: Delay in the treatment of pulmonary TB in a changing demographic scenario. Int J Tuberc Lung Dis. 2006, 10: 305-309.PubMed Gagliotti C, Resi D, Moro ML: Delay in the treatment of pulmonary TB in a changing demographic scenario. Int J Tuberc Lung Dis. 2006, 10: 305-309.PubMed
4.
go back to reference Golub JE, Bur S, Cronin WA, Gange S, Baruch N, Comstock GW, Chaisson RE: Delayed tuberculosis diagnosis and tuberculosis transmission. Int J Tuberc Lung Dis. 2006, 10: 24-30.PubMed Golub JE, Bur S, Cronin WA, Gange S, Baruch N, Comstock GW, Chaisson RE: Delayed tuberculosis diagnosis and tuberculosis transmission. Int J Tuberc Lung Dis. 2006, 10: 24-30.PubMed
5.
go back to reference Asch S, Leake B, Anderson R, Gelberg L: Why do symptomatic patients delay obtaining care for tuberculosis?. Am J Respir Crit Care Med. 1998, 157: 1244-1248. 10.1164/ajrccm.157.4.9709071.PubMed Asch S, Leake B, Anderson R, Gelberg L: Why do symptomatic patients delay obtaining care for tuberculosis?. Am J Respir Crit Care Med. 1998, 157: 1244-1248. 10.1164/ajrccm.157.4.9709071.PubMed
6.
go back to reference Sherman LF, Fujiwara PI, Cook SV, Bazerman LB, Frieden TR: Patient and health care system delays in the diagnosis and treatment of tuberculosis. Int J Tuberc Lung Dis. 1999, 3: 1088-1095.PubMed Sherman LF, Fujiwara PI, Cook SV, Bazerman LB, Frieden TR: Patient and health care system delays in the diagnosis and treatment of tuberculosis. Int J Tuberc Lung Dis. 1999, 3: 1088-1095.PubMed
7.
go back to reference Altet Gomez MN, Alcaide Megias J, Canela Soler J, Mila Auge C, Jimenez Fuentes MA, de Souza Galvao ML, Solsona Peiro J: Estudio del retraso diagnóstico de la tuberculosis pulmonar sintomática [Pulmonary symptomatic tuberculosis’ diagnostic delay study]. Arch Bronconeumol. 2003, 39: 146-152.PubMed Altet Gomez MN, Alcaide Megias J, Canela Soler J, Mila Auge C, Jimenez Fuentes MA, de Souza Galvao ML, Solsona Peiro J: Estudio del retraso diagnóstico de la tuberculosis pulmonar sintomática [Pulmonary symptomatic tuberculosis’ diagnostic delay study]. Arch Bronconeumol. 2003, 39: 146-152.PubMed
8.
go back to reference Farah MG, Rygh JH, Steen TW, Selmer R, Heldal E, Bjune G: Patient and health care system delays in the start of tuberculosis treatment in Norway. BMC Infect Dis. 2006, 6: 33-10.1186/1471-2334-6-33.PubMedPubMedCentral Farah MG, Rygh JH, Steen TW, Selmer R, Heldal E, Bjune G: Patient and health care system delays in the start of tuberculosis treatment in Norway. BMC Infect Dis. 2006, 6: 33-10.1186/1471-2334-6-33.PubMedPubMedCentral
9.
go back to reference Rodger A, Jaffar S, Paynter S, Hayward A, Carless J, Maguire H: Delay in the diagnosis of pulmonary tuberculosis, London, 1998–2000: analysis of surveillance data. BMJ. 2003, 326: 909-910. 10.1136/bmj.326.7395.909.PubMedPubMedCentral Rodger A, Jaffar S, Paynter S, Hayward A, Carless J, Maguire H: Delay in the diagnosis of pulmonary tuberculosis, London, 1998–2000: analysis of surveillance data. BMJ. 2003, 326: 909-910. 10.1136/bmj.326.7395.909.PubMedPubMedCentral
10.
go back to reference Rajeswari R, Chandrasekaran V, Suhadev M, Sivasubramaniam S, Sudha G, Renu G: Factors associated with patient and health system delays in the diagnosis of tuberculosis in South India. Int J Tuberc Lung Dis. 2002, 6: 789-795.PubMed Rajeswari R, Chandrasekaran V, Suhadev M, Sivasubramaniam S, Sudha G, Renu G: Factors associated with patient and health system delays in the diagnosis of tuberculosis in South India. Int J Tuberc Lung Dis. 2002, 6: 789-795.PubMed
11.
go back to reference Xu B, Jiang QW, Xiu Y, Diwan VK: Diagnostic delays in access to tuberculosis care in counties with or without the National Tuberculosis Control Programme in rural China. Int J Tuberc Lung Dis. 2005, 9: 784-790.PubMed Xu B, Jiang QW, Xiu Y, Diwan VK: Diagnostic delays in access to tuberculosis care in counties with or without the National Tuberculosis Control Programme in rural China. Int J Tuberc Lung Dis. 2005, 9: 784-790.PubMed
12.
go back to reference Madebo T, Lindtjørn B: Delay in treatment of pulmonary tuberculosis: an analysis of symptom duration among Ethiopian patients. Med Gen Med. 1999, 18: E6- Madebo T, Lindtjørn B: Delay in treatment of pulmonary tuberculosis: an analysis of symptom duration among Ethiopian patients. Med Gen Med. 1999, 18: E6-
13.
go back to reference Yimer S, Bjune G, Alene G: Diagnostic and treatment delay among pulmonary tuberculosis patients in Ethiopia: a cross sectional study. BMC Infect Dis. 2005, 5: 112-10.1186/1471-2334-5-112.PubMedPubMedCentral Yimer S, Bjune G, Alene G: Diagnostic and treatment delay among pulmonary tuberculosis patients in Ethiopia: a cross sectional study. BMC Infect Dis. 2005, 5: 112-10.1186/1471-2334-5-112.PubMedPubMedCentral
14.
go back to reference Ayuo PO, Diero LO, Owino-Ong'or WD, Mwangi AW: Causes of delay in diagnosis of pulmonary tuberculosis in patients attending a referral hospital in Western Kenya. East Afr Med J. 2008, 85: 263-268.PubMed Ayuo PO, Diero LO, Owino-Ong'or WD, Mwangi AW: Causes of delay in diagnosis of pulmonary tuberculosis in patients attending a referral hospital in Western Kenya. East Afr Med J. 2008, 85: 263-268.PubMed
15.
go back to reference Pronyk RM, Makhubele MB, Hargreaves JR, Tollman SM, Hausler HP: Assessing health seeking behaviour among tuberculosis patients in rural South Africa. Int J Tuberc Lung Dis. 2001, 5: 619-627.PubMed Pronyk RM, Makhubele MB, Hargreaves JR, Tollman SM, Hausler HP: Assessing health seeking behaviour among tuberculosis patients in rural South Africa. Int J Tuberc Lung Dis. 2001, 5: 619-627.PubMed
16.
go back to reference Meintjes G, Schoeman H, Morroni C, Wilson D, Maartens G: Patient and provider delay in tuberculosis suspects from communities with a high HIV prevalence in South Africa: a cross-sectional study. BMC Infect Dis. 2008, 8: 72-10.1186/1471-2334-8-72.PubMedPubMedCentral Meintjes G, Schoeman H, Morroni C, Wilson D, Maartens G: Patient and provider delay in tuberculosis suspects from communities with a high HIV prevalence in South Africa: a cross-sectional study. BMC Infect Dis. 2008, 8: 72-10.1186/1471-2334-8-72.PubMedPubMedCentral
17.
go back to reference Godfrey-Faussett P, Kaunda H, Kamanga J, van Beers S, van Cleeff M, Kumwenda-Phiri R, Tihont V: Why do patients with a cough delay seeking care at Lusaka urban health centres? A health systems research approach. Int J Tuberc Lung Dis. 2002, 6: 796-805.PubMed Godfrey-Faussett P, Kaunda H, Kamanga J, van Beers S, van Cleeff M, Kumwenda-Phiri R, Tihont V: Why do patients with a cough delay seeking care at Lusaka urban health centres? A health systems research approach. Int J Tuberc Lung Dis. 2002, 6: 796-805.PubMed
18.
go back to reference Enwuru CA, Idigbe EO, Ezeobi NV, Otegbeye AF: Care-seeking behavioural patterns, awareness and diagnostic processes in patients with smear- and culture-positive pulmonary tuberculosis in Lagos, Nigeria. Trans R Soc Trop Med Hyg. 2002, 96: 614-616. 10.1016/S0035-9203(02)90328-7.PubMed Enwuru CA, Idigbe EO, Ezeobi NV, Otegbeye AF: Care-seeking behavioural patterns, awareness and diagnostic processes in patients with smear- and culture-positive pulmonary tuberculosis in Lagos, Nigeria. Trans R Soc Trop Med Hyg. 2002, 96: 614-616. 10.1016/S0035-9203(02)90328-7.PubMed
19.
go back to reference Steen TW, Mazonde GN: Pulmonary tuberculosis in Kweneng District, Botswana: delays in diagnosis in 212 smear-positive patients. Int J Tuberc Lung Dis. 1998, 2: 627-634.PubMed Steen TW, Mazonde GN: Pulmonary tuberculosis in Kweneng District, Botswana: delays in diagnosis in 212 smear-positive patients. Int J Tuberc Lung Dis. 1998, 2: 627-634.PubMed
20.
go back to reference Wandwalo E, Kapalata N, Egwaga S, Morkve O: Effectiveness of community-based directly observed treatment for tuberculosis in an urban setting in Tanzania: a randomised controlled trial. Int J Tuberc Lung Dis. 2004, 8: 1248-1254.PubMed Wandwalo E, Kapalata N, Egwaga S, Morkve O: Effectiveness of community-based directly observed treatment for tuberculosis in an urban setting in Tanzania: a randomised controlled trial. Int J Tuberc Lung Dis. 2004, 8: 1248-1254.PubMed
21.
go back to reference Gosoniu GD, Ganapathy S, Kemp J, Auer C, Somma D, Karim F, Weiss MG: Gender and socio-cultural determinants of delay to diagnosis of TB in Bangladesh, India and Malawi. Int J Tuberc Lung Dis. 2008, 12: 848-855.PubMed Gosoniu GD, Ganapathy S, Kemp J, Auer C, Somma D, Karim F, Weiss MG: Gender and socio-cultural determinants of delay to diagnosis of TB in Bangladesh, India and Malawi. Int J Tuberc Lung Dis. 2008, 12: 848-855.PubMed
22.
go back to reference Long NH, Johansson E, Lonnroth K, Eriksson B, Winkvist A, Diwan VK: Longer delays in tuberculosis diagnosis among women in Vietnam. Int J Tuberc Lung Dis. 1999, 3: 388-393.PubMed Long NH, Johansson E, Lonnroth K, Eriksson B, Winkvist A, Diwan VK: Longer delays in tuberculosis diagnosis among women in Vietnam. Int J Tuberc Lung Dis. 1999, 3: 388-393.PubMed
23.
go back to reference Zafran N, Heldal E, Pavlovic S, Vuckovic D, Boe J: Why do our patients die of active tuberculosis in the era of effective therapy?. Tuber Lung Dis. 1994, 75: 329-333. 10.1016/0962-8479(94)90077-9.PubMed Zafran N, Heldal E, Pavlovic S, Vuckovic D, Boe J: Why do our patients die of active tuberculosis in the era of effective therapy?. Tuber Lung Dis. 1994, 75: 329-333. 10.1016/0962-8479(94)90077-9.PubMed
24.
go back to reference Greenaway C, Menzies D, Fanning A, Grewal R, Yuan L, FitzGerald JM: Delay in diagnosis among hospitalized patients with active tuberculosis–predictors and outcomes. Am J Respir Crit Care Med. 2002, 165: 927-933. 10.1164/ajrccm.165.7.2107040.PubMed Greenaway C, Menzies D, Fanning A, Grewal R, Yuan L, FitzGerald JM: Delay in diagnosis among hospitalized patients with active tuberculosis–predictors and outcomes. Am J Respir Crit Care Med. 2002, 165: 927-933. 10.1164/ajrccm.165.7.2107040.PubMed
25.
go back to reference Cronin WA, Golub JE, Lathan MJ, Mukasa LN, Hooper N, Razeq JH, Baruch NG, Mulcahy D, Benjamin WH, Magder LS, et al: Molecular epidemiology of tuberculosis in a low- to moderate-incidence state: are contact investigations enough?. Emerg Infect Dis. 2002, 8: 1271-1279. 10.3201/eid0811.020261.PubMedPubMedCentral Cronin WA, Golub JE, Lathan MJ, Mukasa LN, Hooper N, Razeq JH, Baruch NG, Mulcahy D, Benjamin WH, Magder LS, et al: Molecular epidemiology of tuberculosis in a low- to moderate-incidence state: are contact investigations enough?. Emerg Infect Dis. 2002, 8: 1271-1279. 10.3201/eid0811.020261.PubMedPubMedCentral
27.
go back to reference Wandwalo ER, Morkve O: Delay in tuberculosis case-finding and treatment in Mwanza, Tanzania. Int J Tuberc Lung Dis. 2000, 4: 133-138.PubMed Wandwalo ER, Morkve O: Delay in tuberculosis case-finding and treatment in Mwanza, Tanzania. Int J Tuberc Lung Dis. 2000, 4: 133-138.PubMed
28.
go back to reference Lawn SD, Afful B, Acheampong JW: Pulmonary tuberculosis: diagnostic delay in Ghanaian adults. Int J Tuberc Lung Dis. 1998, 2: 635-640.PubMed Lawn SD, Afful B, Acheampong JW: Pulmonary tuberculosis: diagnostic delay in Ghanaian adults. Int J Tuberc Lung Dis. 1998, 2: 635-640.PubMed
29.
go back to reference Kiwuwa MS, Charles K, Harriet MK: Patient and health service delay in pulmonary tuberculosis patients attending a referral hospital: a cross-sectional study. BMC Public Health. 2005, 5: 122-10.1186/1471-2458-5-122.PubMedPubMedCentral Kiwuwa MS, Charles K, Harriet MK: Patient and health service delay in pulmonary tuberculosis patients attending a referral hospital: a cross-sectional study. BMC Public Health. 2005, 5: 122-10.1186/1471-2458-5-122.PubMedPubMedCentral
30.
go back to reference Odusanya OO, Babafemi JO: Patterns of delays amongst pulmonary tuberculosis patients in Lagos, Nigeria. BMC Public Health. 2004, 4: 18-10.1186/1471-2458-4-18.PubMedPubMedCentral Odusanya OO, Babafemi JO: Patterns of delays amongst pulmonary tuberculosis patients in Lagos, Nigeria. BMC Public Health. 2004, 4: 18-10.1186/1471-2458-4-18.PubMedPubMedCentral
31.
go back to reference Demissie M, Lindtjorn B, Berhane Y: Patient and health service delay in the diagnosis of pulmonary tuberculosis in Ethiopia. BMC Public Health. 2002, 2: 23-10.1186/1471-2458-2-23.PubMedPubMedCentral Demissie M, Lindtjorn B, Berhane Y: Patient and health service delay in the diagnosis of pulmonary tuberculosis in Ethiopia. BMC Public Health. 2002, 2: 23-10.1186/1471-2458-2-23.PubMedPubMedCentral
32.
go back to reference Cambanis A, Ramsay A, Yassin MA, Cuevas LE: Duration and associated factors of patient delay during tuberculosis screening in rural Cameroon. Trop Med Int Health. 2007, 12: 1309-1314. 10.1111/j.1365-3156.2007.01925.x.PubMed Cambanis A, Ramsay A, Yassin MA, Cuevas LE: Duration and associated factors of patient delay during tuberculosis screening in rural Cameroon. Trop Med Int Health. 2007, 12: 1309-1314. 10.1111/j.1365-3156.2007.01925.x.PubMed
33.
go back to reference Liam CK, Tang BG: Delay in the diagnosis and treatment of pulmonary tuberculosis in patients attending a university teaching hospital. Int J Tuberc Lung Dis. 1997, 1: 326-332.PubMed Liam CK, Tang BG: Delay in the diagnosis and treatment of pulmonary tuberculosis in patients attending a university teaching hospital. Int J Tuberc Lung Dis. 1997, 1: 326-332.PubMed
34.
go back to reference Hooi LN: Case-finding for pulmonary tuberculosis in Penang. Med J Malaysia. 1994, 49: 223-230.PubMed Hooi LN: Case-finding for pulmonary tuberculosis in Penang. Med J Malaysia. 1994, 49: 223-230.PubMed
35.
go back to reference Ngamvithayapong J, Yanai H, Winkvist A, Diwan V: Health seeking behaviour and diagnosis for pulmonary tuberculosis in an HIV-epidemic mountainous area of Thailand. Int J Tuberc Lung Dis. 2001, 5: 1013-1020.PubMed Ngamvithayapong J, Yanai H, Winkvist A, Diwan V: Health seeking behaviour and diagnosis for pulmonary tuberculosis in an HIV-epidemic mountainous area of Thailand. Int J Tuberc Lung Dis. 2001, 5: 1013-1020.PubMed
36.
go back to reference Rojpibulstit M, Kanjanakiritamrong J, Chongsuvivatwong V: Patient and health system delays in the diagnosis of tuberculosis in Southern Thailand after health care reform. Int J Tuberc Lung Dis. 2006, 10: 422-428.PubMed Rojpibulstit M, Kanjanakiritamrong J, Chongsuvivatwong V: Patient and health system delays in the diagnosis of tuberculosis in Southern Thailand after health care reform. Int J Tuberc Lung Dis. 2006, 10: 422-428.PubMed
37.
go back to reference Guneylioglu D, Yilmaz A, Bilgin S, Bayram U, Akkaya E: Factors affecting delays in diagnosis and treatment of pulmonary tuberculosis in a tertiary care hospital in Istanbul, Turkey. Med Sci Monit. 2004, 10: CR62-CR67.PubMed Guneylioglu D, Yilmaz A, Bilgin S, Bayram U, Akkaya E: Factors affecting delays in diagnosis and treatment of pulmonary tuberculosis in a tertiary care hospital in Istanbul, Turkey. Med Sci Monit. 2004, 10: CR62-CR67.PubMed
Metadata
Title
Patient and health system delay among patients with pulmonary tuberculosis in Beira city, Mozambique
Authors
Abuchahama Saifodine
Paula Samo Gudo
Mohsin Sidat
James Black
Publication date
01-12-2013
Publisher
BioMed Central
Published in
BMC Public Health / Issue 1/2013
Electronic ISSN: 1471-2458
DOI
https://doi.org/10.1186/1471-2458-13-559

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