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Published in: Virchows Archiv 4/2020

01-10-2020 | Pathology | Review and Perspectives

The use of digital microscopy as a teaching method for human pathology: a systematic review

Authors: Carla Isabelly Rodrigues-Fernandes, Paul M. Speight, Syed Ali Khurram, Anna Luíza Damaceno Araújo, Danyel Elias da Cruz Perez, Felipe Paiva Fonseca, Márcio Ajudarte Lopes, Oslei Paes de Almeida, Pablo Agustin Vargas, Alan Roger Santos-Silva

Published in: Virchows Archiv | Issue 4/2020

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Abstract

Since digital microscopy (DM) has become a useful alternative to conventional light microscopy (CLM), several approaches have been used to evaluate students’ performance and perception. This systematic review aimed to integrate data regarding the use of DM for education in human pathology, determining whether this technology can be an adequate learning tool, and an appropriate method to evaluate students’ performance. Following a specific search strategy and eligibility criteria, three electronic databases were searched and several articles were screened. Eight studies involving medical and dental students were included. The test of performance comprised diagnostic and microscopic description, clinical features, differential, and final diagnoses of the specimens. The students’ achievements were equivalent, similar or higher using DM in comparison with CLM in four studies. All publications employed question surveys to assess the students’ perceptions, especially regarding the easiness of equipment use, quality of images, and preference for one method. Seven studies (87.5%) indicated the students’ support of DM as an appropriate method for learning. The quality assessment categorized most studies as having a low bias risk (75%). This study presents the efficacy of DM for human pathology education, although the high heterogeneity of the included articles did not permit outlining a specific method of performance evaluation.
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Literature
1.
go back to reference Boyce BF (2015) Whole slide imaging: uses and limitations for surgical pathology and teaching. Biotech Histochem 90:321–330CrossRef Boyce BF (2015) Whole slide imaging: uses and limitations for surgical pathology and teaching. Biotech Histochem 90:321–330CrossRef
2.
go back to reference Saco A, Bombi JA, Garcia A, Ramírez J, Ordi J (2016) Current status of whole-slide imaging in education. Pathobiology 83:79–88CrossRef Saco A, Bombi JA, Garcia A, Ramírez J, Ordi J (2016) Current status of whole-slide imaging in education. Pathobiology 83:79–88CrossRef
3.
go back to reference Merk M, Knuechel R, Perez-Bouza A (2010) Web-based virtual microscopy at the RWTH Aachen University: didactic concept, methods and analysis of acceptance by the students. Ann Anat 192:383–387CrossRef Merk M, Knuechel R, Perez-Bouza A (2010) Web-based virtual microscopy at the RWTH Aachen University: didactic concept, methods and analysis of acceptance by the students. Ann Anat 192:383–387CrossRef
4.
go back to reference Higgins C (2015) Applications and challenges of digital pathology and whole slide imaging. Biotech Histochem 90:341–347CrossRef Higgins C (2015) Applications and challenges of digital pathology and whole slide imaging. Biotech Histochem 90:341–347CrossRef
5.
go back to reference Koch LH, Lampros JN, Delong LK, Chen SC, Woosley JT, Hood AF (2009) Randomized comparison of virtual microscopy and traditional glass microscopy in diagnostic accuracy among dermatology and pathology residents. Hum Pathol 40:662–667CrossRef Koch LH, Lampros JN, Delong LK, Chen SC, Woosley JT, Hood AF (2009) Randomized comparison of virtual microscopy and traditional glass microscopy in diagnostic accuracy among dermatology and pathology residents. Hum Pathol 40:662–667CrossRef
6.
go back to reference McCready ZR, Jham BC (2013) Dental students’ perceptions of the use of digital microscopy as part of an oral pathology curriculum. J Den Educ. 77:1624–1628CrossRef McCready ZR, Jham BC (2013) Dental students’ perceptions of the use of digital microscopy as part of an oral pathology curriculum. J Den Educ. 77:1624–1628CrossRef
7.
go back to reference Ariana A, Amin M, Pakneshan S, Dolan-Evans E, Lam AK (2016) Integration of traditional and E-learning methods to improve learning outcomes for dental students in histopathology. J Den Educ. 80:1140–1148CrossRef Ariana A, Amin M, Pakneshan S, Dolan-Evans E, Lam AK (2016) Integration of traditional and E-learning methods to improve learning outcomes for dental students in histopathology. J Den Educ. 80:1140–1148CrossRef
8.
go back to reference Al-Janabi S, Huisman A, Van Diest PJ (2012) Digital pathology: current status and future perspectives. Histopathology. 61:1–9CrossRef Al-Janabi S, Huisman A, Van Diest PJ (2012) Digital pathology: current status and future perspectives. Histopathology. 61:1–9CrossRef
9.
go back to reference Araújo ALD, Amaral-Silva GK, Fonseca FP, Palmier NR, Lopes MA, Speight PM, de Almeida OP, Vargas PA, Santos-Silva AR (2018) Validation of digital microscopy in the histopathological diagnoses of oral diseases. Virchows Arch. 473:321–327CrossRef Araújo ALD, Amaral-Silva GK, Fonseca FP, Palmier NR, Lopes MA, Speight PM, de Almeida OP, Vargas PA, Santos-Silva AR (2018) Validation of digital microscopy in the histopathological diagnoses of oral diseases. Virchows Arch. 473:321–327CrossRef
10.
go back to reference Fónyad L, Gerely L, Cserneky M, Molnár B, Matolcsy A (2010) Shifting gears higher – digital slides in graduate education – 4 years experience at Semmelweis University. Diagn Pathol. 5:73CrossRef Fónyad L, Gerely L, Cserneky M, Molnár B, Matolcsy A (2010) Shifting gears higher – digital slides in graduate education – 4 years experience at Semmelweis University. Diagn Pathol. 5:73CrossRef
11.
go back to reference Szymas J, Lundin M (2011) Five years of experience teaching pathology to dental students using the WebMicroscope. Diagn Pathol. 30:6 Szymas J, Lundin M (2011) Five years of experience teaching pathology to dental students using the WebMicroscope. Diagn Pathol. 30:6
12.
go back to reference Alotaibi O, ALQahtani D (2016) Measuring dental students' preference: a comparison of light microscopy and virtual microscopy as teaching tools in oral histology and pathology. Saudi Dent J 28:169–173CrossRef Alotaibi O, ALQahtani D (2016) Measuring dental students' preference: a comparison of light microscopy and virtual microscopy as teaching tools in oral histology and pathology. Saudi Dent J 28:169–173CrossRef
13.
go back to reference Brierley DJ, Speight PM, Hunter KD, Farthing P (2017) Using virtual microscopy to deliver an integrated oral pathology course for undergraduate dental students. Br Dent J. 223:115–120CrossRef Brierley DJ, Speight PM, Hunter KD, Farthing P (2017) Using virtual microscopy to deliver an integrated oral pathology course for undergraduate dental students. Br Dent J. 223:115–120CrossRef
14.
go back to reference Braun MW, Kearns KD (2008) Improved learning efficiency and increased student collaboration through use of virtual microscopy in the teaching of human pathology. Anat Sci Educ 6:240–246CrossRef Braun MW, Kearns KD (2008) Improved learning efficiency and increased student collaboration through use of virtual microscopy in the teaching of human pathology. Anat Sci Educ 6:240–246CrossRef
15.
go back to reference Fonseca FP, Santos-Silva AR, Lopes MA et al (2015) Transition from glass to digital slide microscopy in the teaching of oral pathology in a Brazilian dental school. Med Oral Patol Oral Cir Bucal. 20:e17–e22CrossRef Fonseca FP, Santos-Silva AR, Lopes MA et al (2015) Transition from glass to digital slide microscopy in the teaching of oral pathology in a Brazilian dental school. Med Oral Patol Oral Cir Bucal. 20:e17–e22CrossRef
16.
go back to reference Fernandes CIR, Bonan RF, Bonan PRF, Leonel ACLS, Carvalho EJA, de Castro JFL, Perez DEC (2018) Dental students' perceptions and performance in use of conventional and virtual microscopy in oral pathology. J Dent Educ. 82:883–890CrossRef Fernandes CIR, Bonan RF, Bonan PRF, Leonel ACLS, Carvalho EJA, de Castro JFL, Perez DEC (2018) Dental students' perceptions and performance in use of conventional and virtual microscopy in oral pathology. J Dent Educ. 82:883–890CrossRef
17.
go back to reference Kumar RK, Velan GM, Korell SO, Kandara M, Dee FR, Wakefield D (2004) Virtual microscopy for learning and assessment in pathology. J Pathol. 204:613–618CrossRef Kumar RK, Velan GM, Korell SO, Kandara M, Dee FR, Wakefield D (2004) Virtual microscopy for learning and assessment in pathology. J Pathol. 204:613–618CrossRef
18.
go back to reference Ordi O, Bombó JA, Martínez A et al (2015) Virtual microscopy in the undergraduate teaching of pathology. J Pathol Inform. 6:1CrossRef Ordi O, Bombó JA, Martínez A et al (2015) Virtual microscopy in the undergraduate teaching of pathology. J Pathol Inform. 6:1CrossRef
19.
go back to reference Walkowski S, Lundin M, Szymas J, Lundin J (2014) Students’ performance during practical examination on whole slide images using view path tracking. Diagn Pathol. 9:208CrossRef Walkowski S, Lundin M, Szymas J, Lundin J (2014) Students’ performance during practical examination on whole slide images using view path tracking. Diagn Pathol. 9:208CrossRef
20.
go back to reference Moher D, Liberati A, Tetzlaff J et al (2009) Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Ann Intern Med. 151:264–269CrossRef Moher D, Liberati A, Tetzlaff J et al (2009) Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Ann Intern Med. 151:264–269CrossRef
21.
go back to reference Wilson AB, Taylor MA, Klein BA et al (2016) Meta-analysis and review of learner performance and preference: virtual versus optical microscopy. Med Educ 50:428–440CrossRef Wilson AB, Taylor MA, Klein BA et al (2016) Meta-analysis and review of learner performance and preference: virtual versus optical microscopy. Med Educ 50:428–440CrossRef
23.
go back to reference Ouzzani M, Hammady H, Fedorowicz Z et al (2016) Rayyan—a web and mobile app for systematic reviews. Syst Ver. 5:210 Ouzzani M, Hammady H, Fedorowicz Z et al (2016) Rayyan—a web and mobile app for systematic reviews. Syst Ver. 5:210
24.
go back to reference Moola S, Munn Z, Tufanaru C, Aromataris E, Sears K, Sfetcu R, Currie M, Qureshi R, Mattis P, Lisy K, Mu P-F (2017) Chapter 7: Systematic reviews of etiology and risk. In: Aromataris E, Munn Z (eds) Joanna Briggs Institute Reviewer's Manual. The Joanna Briggs Institute. Available from https://reviewersmanual.joannabriggs.org/ Moola S, Munn Z, Tufanaru C, Aromataris E, Sears K, Sfetcu R, Currie M, Qureshi R, Mattis P, Lisy K, Mu P-F (2017) Chapter 7: Systematic reviews of etiology and risk. In: Aromataris E, Munn Z (eds) Joanna Briggs Institute Reviewer's Manual. The Joanna Briggs Institute. Available from https://​reviewersmanual.​joannabriggs.​org/​
26.
go back to reference Farah CS, Maybury T (2009) Implementing digital technology to enhance student learning of pathology. Eur J Dent Educ 13:172–178CrossRef Farah CS, Maybury T (2009) Implementing digital technology to enhance student learning of pathology. Eur J Dent Educ 13:172–178CrossRef
27.
go back to reference Brick KE, Sluzevich JC, Cappel MA, DiCaudo DJ, Comfere NI, Wieland CN (2013) Comparison of virtual microscopy and glass slide microscopy among dermatology residents during a simulated in-training examination. J Cutan Pathol 40:807–811CrossRef Brick KE, Sluzevich JC, Cappel MA, DiCaudo DJ, Comfere NI, Wieland CN (2013) Comparison of virtual microscopy and glass slide microscopy among dermatology residents during a simulated in-training examination. J Cutan Pathol 40:807–811CrossRef
28.
go back to reference Nauhria S, Ramdass P (2019) Randomized cross-over study and a qualitative analysis comparing virtual microscopy and light microscopy for learning undergraduate histopathology. Indian J Pathol Microbiol. 62:84–90CrossRef Nauhria S, Ramdass P (2019) Randomized cross-over study and a qualitative analysis comparing virtual microscopy and light microscopy for learning undergraduate histopathology. Indian J Pathol Microbiol. 62:84–90CrossRef
30.
go back to reference Hassel LA, Fung KM, Chaser B (2011) Digital slides and ACGME resident competencies in anatomic pathology: An altered paradigm for acquisition and assessment. J Pathol Inform. 2:27CrossRef Hassel LA, Fung KM, Chaser B (2011) Digital slides and ACGME resident competencies in anatomic pathology: An altered paradigm for acquisition and assessment. J Pathol Inform. 2:27CrossRef
31.
go back to reference Triola MM, Holloway WJ (2011) Enhanced virtual microscopy for collaborative education. BMC Med Educ. 11:4CrossRef Triola MM, Holloway WJ (2011) Enhanced virtual microscopy for collaborative education. BMC Med Educ. 11:4CrossRef
32.
go back to reference Lee LMJ, Goldman HM, Hortsch M (2018) The virtual microscopy database-sharing digital microscope images for research and education. Anat Sci Educ. 11:510–515CrossRef Lee LMJ, Goldman HM, Hortsch M (2018) The virtual microscopy database-sharing digital microscope images for research and education. Anat Sci Educ. 11:510–515CrossRef
33.
go back to reference Mione S, Valcke M, Cornelissen M (2013) Evaluation of virtual microscopy in medical histology teaching. Anat Sci Educ. 6:307–315CrossRef Mione S, Valcke M, Cornelissen M (2013) Evaluation of virtual microscopy in medical histology teaching. Anat Sci Educ. 6:307–315CrossRef
34.
go back to reference Volynskaya Z, Evans AJ, Asa SL (2017) Clinical applications of whole-slide imaging in anatomic pathology. Adv Anat Pathol. 24:215–221CrossRef Volynskaya Z, Evans AJ, Asa SL (2017) Clinical applications of whole-slide imaging in anatomic pathology. Adv Anat Pathol. 24:215–221CrossRef
46.
go back to reference Bankhead P, Loughrey MB, Fernández JA, Dombrowski Y, McArt DG, Dunne PD et al (2017, 2017) QuPath: Open source software for digital pathology image analysis. Sci Rep 7(1) Bankhead P, Loughrey MB, Fernández JA, Dombrowski Y, McArt DG, Dunne PD et al (2017, 2017) QuPath: Open source software for digital pathology image analysis. Sci Rep 7(1)
48.
go back to reference Dee FR (2009) Virtual microscopy in pathology education. Hum Pathol. 40:1112–1221CrossRef Dee FR (2009) Virtual microscopy in pathology education. Hum Pathol. 40:1112–1221CrossRef
49.
go back to reference Mirham L, Naugler C, Hayes M et al (2016) Performance of residents using digital images versus glass slides on certification examination in anatomical pathology: a mixed methods pilot study. CMAJ Open. 25:E88–E94CrossRef Mirham L, Naugler C, Hayes M et al (2016) Performance of residents using digital images versus glass slides on certification examination in anatomical pathology: a mixed methods pilot study. CMAJ Open. 25:E88–E94CrossRef
50.
go back to reference Pantanowitz L, Sinard JH, Henricks WH, Fatheree LA, Carter AB, Contis L, Beckwith BA, Evans AJ, Lal A, Parwani AV, College of American Pathologists Pathology and Laboratory Quality Center (2013) Validating whole slide imaging for diagnostic purposes in pathology: guideline from the College of American Pathologists Pathology and Laboratory Quality Center. Arch Pathol Lab Med. 137:1710–1722CrossRef Pantanowitz L, Sinard JH, Henricks WH, Fatheree LA, Carter AB, Contis L, Beckwith BA, Evans AJ, Lal A, Parwani AV, College of American Pathologists Pathology and Laboratory Quality Center (2013) Validating whole slide imaging for diagnostic purposes in pathology: guideline from the College of American Pathologists Pathology and Laboratory Quality Center. Arch Pathol Lab Med. 137:1710–1722CrossRef
Metadata
Title
The use of digital microscopy as a teaching method for human pathology: a systematic review
Authors
Carla Isabelly Rodrigues-Fernandes
Paul M. Speight
Syed Ali Khurram
Anna Luíza Damaceno Araújo
Danyel Elias da Cruz Perez
Felipe Paiva Fonseca
Márcio Ajudarte Lopes
Oslei Paes de Almeida
Pablo Agustin Vargas
Alan Roger Santos-Silva
Publication date
01-10-2020
Publisher
Springer Berlin Heidelberg
Keyword
Pathology
Published in
Virchows Archiv / Issue 4/2020
Print ISSN: 0945-6317
Electronic ISSN: 1432-2307
DOI
https://doi.org/10.1007/s00428-020-02908-3

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