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Diagnostic Pathology
Published in: Diagnostic Pathology 1/2012

Open Access 01-12-2012 | Case Report

Pathological femoral fractures due to osteomalacia associated with adefovir dipivoxil treatment for hepatitis B: a case report

Authors: Motoyuki Tanaka, Takao Setoguchi, Yasuhiro Ishidou, Yoshiya Arishima, Masataka Hirotsu, Yoshinobu Saitoh, Shunsuke Nakamura, Hironori Kakoi, Satoshi Nagano, Masahiro Yokouchi, Junichi Kamizono, Setsuro Komiya

Published in: Diagnostic Pathology | Issue 1/2012

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Abstract

We present a case of a 62-year-old man who underwent total hip arthroplasty for treatment of pathologic femoral neck fracture associated with adefovir dipivoxil-induced osteomalacia. He had a 13-month history of bone pain involving his shoulders, hips, and knee. He received adefovir dipivoxil for treatment of lamivudine-resistant hepatitis B virus infection for 5 years before the occurrence of femoral neck fracture. Orthopedic surgeons should be aware of osteomalacia and pathological hip fracture caused by drug-induced renal dysfunction, which results in Fanconi’s syndrome.

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Metadata
Title
Pathological femoral fractures due to osteomalacia associated with adefovir dipivoxil treatment for hepatitis B: a case report
Authors
Motoyuki Tanaka
Takao Setoguchi
Yasuhiro Ishidou
Yoshiya Arishima
Masataka Hirotsu
Yoshinobu Saitoh
Shunsuke Nakamura
Hironori Kakoi
Satoshi Nagano
Masahiro Yokouchi
Junichi Kamizono
Setsuro Komiya
Publication date
01-12-2012
Publisher
BioMed Central
Published in
Diagnostic Pathology / Issue 1/2012
Electronic ISSN: 1746-1596
DOI
https://doi.org/10.1186/1746-1596-7-108

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