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Published in: Archives of Gynecology and Obstetrics 1/2012

01-07-2012 | General Gynecology

Pathogenesis of endometriosis: the role of genetics, inflammation and oxidative stress

Authors: A. Augoulea, A. Alexandrou, M. Creatsa, N. Vrachnis, I. Lambrinoudaki

Published in: Archives of Gynecology and Obstetrics | Issue 1/2012

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Abstract

Introduction

Endometriosis is defined as the presence of endometrial tissue outside the uterine cavity.

Materials and Methods

The etiology of this multifactorial disease is still unresolved and an increasing number of studies suggest that genetic, hormonal, environmental, immunological and oxidative factors may all play an important role in the pathogenesis of this disorder.

Conclusions

In this literature review, inflammatory activity, oxidative stress as well as genetic abnormalities and mutations have been studied in an effort to identify factors predisposing to endometriosis.
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Metadata
Title
Pathogenesis of endometriosis: the role of genetics, inflammation and oxidative stress
Authors
A. Augoulea
A. Alexandrou
M. Creatsa
N. Vrachnis
I. Lambrinoudaki
Publication date
01-07-2012
Publisher
Springer-Verlag
Published in
Archives of Gynecology and Obstetrics / Issue 1/2012
Print ISSN: 0932-0067
Electronic ISSN: 1432-0711
DOI
https://doi.org/10.1007/s00404-012-2357-8

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